Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-02-27 | SHERMAN JEFFREY W | Director | +Buy | 5,000 | $5.00 | $25,000 |
| 2026-02-27 | THOMAS FRANK E | Director | +Buy | 5,000 | $5.00 | $25,000 |
| 2026-02-27 | Hamilton Thomas Edward | Director | +Buy | 100,000 | $5.00 | $500,000 |
| 2026-02-27 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 1,084,012 | $5.00 | $5M |
| 2026-02-27 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 831,978 | $5.00 | $4M |
| 2026-02-27 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 2,000,000 | $5.00 | $10M |
| 2026-02-27 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 1,084,010 | $5.00 | $5M |
| 2026-01-26 | Celano Michael | Officer | +Grant | 37,604 | — | — |
| 2026-01-26 | BEN-MAIMON CAROLE | Director,Officer | +Grant | 100,100 | — | — |
| 2026-01-26 | Clayton Russell | Officer | +Grant | 25,637 | — | — |
| 2026-01-26 | Shankar Gopi | Officer | +Grant | 25,637 | — | — |
| 2025-07-31 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 2,599,932 | $3.20 | $8M |
| 2025-07-31 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 3,387,539 | $3.20 | $11M |
| 2025-07-31 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwner,Other | +Buy | 3,387,529 | $3.20 | $11M |
| 2025-01-22 | Celano Michael | Officer | +Grant | 34,185 | — | — |
| 2025-01-22 | BEN-MAIMON CAROLE | Director,Officer | +Grant | 91,000 | — | — |
| 2025-01-22 | Clayton Russell | Officer | +Grant | 23,306 | — | — |
| 2025-01-22 | Shankar Gopi | Officer | +Grant | 23,306 | — | — |
| 2024-02-16 | Deerfield Mgmt L.P. | Director,TenPercentOwner,Other | +Buy | 1,430,205 | $8.74 | $12M |
| 2024-02-16 | Deerfield Mgmt L.P. | Director,TenPercentOwner,Other | +Buy | 1,430,206 | $8.74 | $13M |
| 2024-02-16 | Deerfield Mgmt L.P. | Director,TenPercentOwner,Other | +Buy | 1,430,206 | $8.74 | $13M |
| 2024-02-16 | Hamilton Thomas Edward | Director | +Buy | 57,208 | $8.74 | $499,998 |
| 2024-02-14 | THOMAS FRANK E | Director | +Buy | 2,000 | $11.00 | $22,000 |
| 2024-01-17 | BEN-MAIMON CAROLE | Director,Officer | +Grant | 66,125 | — | — |
| 2024-01-17 | Clayton Russell | Officer | +Grant | 22,500 | — | — |
| 2024-01-17 | Celano Michael | Officer | +Grant | 31,250 | — | — |
| 2024-01-17 | Shankar Gopi | Officer | +Grant | 22,500 | — | — |
| 2023-12-07 | Shankar Gopi | Officer | +Buy | 5,000 | $3.73 | $18,650 |
| 2023-05-17 | Truitt Joseph | Director | +Buy | 2,750 | $3.73 | $10,258 |
| 2023-05-17 | BEN-MAIMON CAROLE | Director,Officer | +Buy | 5,000 | $3.71 | $18,550 |
| 2023-05-17 | Celano Michael | Officer | +Buy | 5,000 | $3.73 | $18,650 |
| 2023-01-31 | BEN-MAIMON CAROLE | Director,Officer | +Grant | 205,000 | — | — |
| 2023-01-31 | Celano Michael | Officer | +Grant | 76,000 | — | — |
| 2022-09-16 | BEN-MAIMON CAROLE | Director,Officer | +Buy | 31,746 | $3.15 | $100,000 |
| 2022-09-16 | Celano Michael | Officer | +Buy | 31,746 | $3.15 | $100,000 |
| 2022-09-16 | Hamilton Thomas Edward | Director | +Buy | 317,460 | $3.15 | $999,999 |
| 2022-09-16 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwnerOther | +Buy | 2,777,777 | $3.15 | $9M |
| 2022-09-16 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwnerOther | +Buy | 2,777,777 | $3.15 | $9M |
| 2022-09-16 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwnerOther | +Buy | 2,777,777 | $3.15 | $9M |
| 2022-09-16 | Deerfield Mgmt HIF, L.P. | Director,TenPercentOwnerOther | +Buy | 2,777,777 | $3.15 | $9M |
| 2021-06-30 | Hamilton Thomas Edward | Director | +Buy | 56,710 | $8.75 | $496,213 |
| 2021-06-30 | Deerfield Mgmt IV, L.P. | Director,TenPercentOwnerOther | +Buy | 228,571 | $8.75 | $2M |
| 2021-06-30 | Deerfield Mgmt IV, L.P. | Director,TenPercentOwnerOther | +Buy | 228,569 | $8.75 | $2M |
| 2021-06-30 | Deerfield Mgmt IV, L.P. | Director,TenPercentOwnerOther | +Buy | 228,570 | $8.75 | $2M |
| 2020-06-26 | BEN-MAIMON CAROLE | Director,Officer | +Other | 25,083 | — | — |
| 2020-06-26 | CHONDRIAL THERAPEUTICS HOLDINGS, LLC | TenPercentOwner | −Other | 6,091,242 | — | — |
| 2020-06-26 | Hamilton Thomas Edward | Director | +Other | 133,420 | — | — |
| 2020-06-26 | Hamilton Thomas Edward | Director | +Other | 159,433 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.