Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-29 | Booth Bruce | Director | −Sell | 3,024 | $107.76 | $325,866 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 2,318 | $106.63 | $247,168 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 848 | $105.78 | $89,701 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 19,093 | $107.76 | $2M |
| 2026-06-29 | Booth Bruce | Director | −Sell | 14,613 | $106.63 | $2M |
| 2026-06-29 | Booth Bruce | Director | −Sell | 5,471 | $105.78 | $578,722 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 1,239 | $109.75 | $135,980 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 1,688 | $108.28 | $182,777 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 907 | $111.20 | $100,858 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 7,602 | $110.67 | $841,313 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 1,199 | $110.67 | $132,693 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 157 | $111.20 | $17,458 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 7,833 | $109.75 | $859,672 |
| 2026-06-29 | Booth Bruce | Director | −Sell | 10,658 | $108.28 | $1M |
| 2026-06-26 | BIOTECHNOLOGY VALUE FUND II LP | Director,Other | −Sell | 627,597 | $106.50 | $67M |
| 2026-06-26 | BIOTECHNOLOGY VALUE FUND II LP | Director,Other | −Sell | 113,289 | $106.50 | $12M |
| 2026-06-26 | BIOTECHNOLOGY VALUE FUND II LP | Director,Other | −Sell | 51,858 | $106.50 | $6M |
| 2026-06-26 | BIOTECHNOLOGY VALUE FUND II LP | Director,Other | −Sell | 837,914 | $106.50 | $89M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 1,729 | $118.66 | $205,163 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 3,069 | $117.85 | $361,682 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 1,701 | $117.09 | $199,170 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 952 | $115.69 | $110,137 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 3,896 | $114.94 | $447,806 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 2,083 | $113.97 | $237,400 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 78 | $112.49 | $8,774 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 1,442 | $111.51 | $160,797 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 1,579 | $110.49 | $174,464 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 4,562 | $109.79 | $500,862 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 32,402 | $108.14 | $4M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 3,958 | $107.57 | $425,762 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 12,390 | $118.66 | $1M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 22,046 | $117.85 | $3M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 12,181 | $117.09 | $1M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 6,821 | $115.69 | $789,121 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 27,951 | $114.94 | $3M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 14,913 | $113.97 | $2M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 555 | $112.49 | $62,432 |
| 2026-06-26 | Booth Bruce | Director | −Sell | 10,366 | $111.51 | $1M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 11,277 | $110.49 | $1M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 32,624 | $109.79 | $4M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 231,007 | $108.14 | $25M |
| 2026-06-26 | Booth Bruce | Director | −Sell | 28,296 | $107.57 | $3M |
| 2026-06-25 | Goodman Noah | Officer | +Exercise | 5,000 | $21.05 | $105,250 |
| 2026-06-25 | Goodman Noah | Officer | −Sell | 2,500 | $109.00 | $272,500 |
| 2026-06-25 | Goodman Noah | Officer | −Sell | 2,500 | $119.00 | $297,500 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 159 | $108.02 | $17,175 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 9,994 | $107.30 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 2,646 | $118.60 | $313,816 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 3,359 | $117.50 | $394,683 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 11,375 | $116.53 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 8,389 | $115.57 | $969,517 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,289 | $114.65 | $147,784 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,437 | $113.70 | $163,387 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 100 | $111.89 | $11,189 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 14,351 | $108.83 | $2M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,915 | $110.30 | $211,225 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 614 | $110.79 | $68,025 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 719 | $111.89 | $80,449 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 10,215 | $113.70 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 9,229 | $114.65 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 58,205 | $115.57 | $7M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 81,500 | $116.53 | $9M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 24,268 | $117.50 | $3M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 19,089 | $118.60 | $2M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,399 | $107.30 | $150,113 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 23 | $108.02 | $2,484 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 2,011 | $108.83 | $218,857 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 86 | $110.79 | $9,528 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 265 | $110.30 | $29,230 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 3,507 | $127.37 | $446,687 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 223 | $126.71 | $28,256 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 522 | $125.82 | $65,678 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,639 | $124.61 | $204,236 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,517 | $123.62 | $187,532 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 698 | $122.67 | $85,624 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 5,689 | $121.38 | $690,531 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 15,660 | $120.66 | $2M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 5,144 | $119.71 | $615,788 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 337 | $129.61 | $43,679 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 2,197 | $128.69 | $282,732 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 25,075 | $127.37 | $3M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 1,609 | $126.71 | $203,876 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 3,716 | $125.82 | $467,547 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 11,711 | $124.61 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 10,860 | $123.62 | $1M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 4,977 | $122.67 | $610,529 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 40,774 | $121.38 | $5M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 112,299 | $120.66 | $14M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 37,179 | $119.71 | $4M |
| 2026-06-25 | Booth Bruce | Director | −Sell | 46 | $129.61 | $5,962 |
| 2026-06-25 | Booth Bruce | Director | −Sell | 305 | $128.69 | $39,250 |
| 2026-06-24 | Booth Bruce | Director | −Sell | 2,029 | $101.14 | $205,213 |
| 2026-06-24 | Booth Bruce | Director | −Sell | 14,490 | $101.14 | $1M |
| 2026-06-24 | Booth Bruce | Director | −Sell | 14,513 | $100.42 | $1M |
| 2026-06-24 | Booth Bruce | Director | −Sell | 103,688 | $100.42 | $10M |
| 2026-06-23 | Booth Bruce | Director | −Sell | 173 | $99.98 | $17,297 |
| 2026-06-23 | Booth Bruce | Director | −Sell | 1,235 | $99.98 | $123,475 |
| 2026-06-22 | Goodman Noah | Officer | −Sell | 2,500 | $99.00 | $247,500 |
| 2026-06-22 | Goodman Noah | Officer | +Exercise | 2,500 | $21.05 | $52,625 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 1,253 | $102.48 | $128,407 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 918 | $101.61 | $93,278 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 7,879 | $100.17 | $789,239 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 7,319 | $99.57 | $728,753 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 3,603 | $98.58 | $355,184 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 2,247 | $97.68 | $219,487 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 2,919 | $96.24 | $280,925 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 1,648 | $95.12 | $156,758 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 286 | $94.48 | $27,021 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 2,179 | $92.14 | $200,773 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 8,990 | $102.48 | $921,295 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 6,597 | $101.61 | $670,321 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 56,348 | $100.17 | $6M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 52,442 | $99.57 | $5M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 25,976 | $98.58 | $3M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 16,084 | $97.68 | $2M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 20,903 | $96.24 | $2M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 11,783 | $95.12 | $1M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 2,035 | $94.48 | $192,267 |
| 2026-06-22 | Booth Bruce | Director | −Sell | 14,921 | $92.14 | $1M |
| 2026-06-22 | Booth Bruce | Director | −Sell | 9,584 | $104.38 | $1M |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.