| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | Lynx1 Capital Management LP | 1,538,2961.5M | $17M | 10.67% | ADD 127% |
| 2 | NEA Management Company, LLC | 1,297,8931.3M | $15M | 9.00% | ADD 19% |
| 3 | Atlas Venture Life Science Advisors, LLC | 1,137,1491.1M | $13M | 7.88% | — |
| 4 | Balyasny Asset Management L.P. | 1,040,0541.0M | $12M | 7.21% | NEW† |
| 5 | Venrock Adviser, LLC | 1,009,5001.0M | $11M | 7.00% | NEW† |
| 6 | Affinity Asset Advisors, LLC | 706,904706,904 | $8M | 4.90% | NEW† |
| 7 | Nantahala Capital Management, LLC | 660,036660,036 | $7M | 4.58% | ADD 10% |
| 8 | ADAR1 Capital Management, LLC | 540,054540,054 | $6M | 3.74% | NEW† |
| 9 | BlackRock, Inc. | 460,006460,006 | $5M | 3.19% | — |
| 10 | Driehaus Capital Management LLC | 450,045450,045 | $5M | 3.12% | NEW† |
| 11 | TCG Crossover Management, LLC | 416,301416,301 | $5M | 2.89% | — |
| 12 | Siren, L.L.C. | 347,718347,718 | $4M | 2.41% | — |
| 13 | VANGUARD CAPITAL MANAGEMENT LLC | 310,913310,913 | $4M | 2.16% | NEW† |
| 14 | 72 Investment Holdings, LLC | 276,831276,831 | $3M | 1.92% | — |
| 15 | AQR CAPITAL MANAGEMENT LLC | 267,755267,755 | $3M | 1.86% | ADD 559% |
| 16 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 228,400228,400 | $3M | 1.58% | NEW |
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 173,643173,643 | $2M | 1.20% | ADD 7% |
| 18 | TWO SIGMA INVESTMENTS, LP | 165,472165,472 | $2M | 1.15% | ADD 110% |
| 19 | VANGUARD PORTFOLIO MANAGEMENT LLC | 148,559148,559 | $2M | 1.03% | NEW |
| 20 | STATE STREET CORP | 140,341140,341 | $2M | 0.97% | TRIM -4% |
| 21 | RENAISSANCE TECHNOLOGIES LLC | 136,227136,227 | $2M | 0.94% | ADD 82% |
| 22 | JANE STREET GROUP, LLC | 115,704115,704 | $1M | 0.80% | TRIM -60% |
| 23 | Kalehua Capital Management LLC | 109,376109,376 | $1M | 0.76% | NEW |
| 24 | MILLENNIUM MANAGEMENT LLC | 63,60663,606 | $720,020 | 0.44% | TRIM -61% |
| 25 | EMERALD MUTUAL FUND ADVISERS TRUST | 62,85562,855 | $711,519 | 0.44% | TRIM -4% |
| 26 | F/m Investments LLC | 62,85562,855 | $711,519 | 0.44% | TRIM -4% |
| 27 | JPMORGAN CHASE & CO | 68,50068,500 | $704,180 | 0.47% | ADD 2314% |
| 28 | XTX Topco Ltd | 60,47260,472 | $684,543 | 0.42% | ADD 6% |
| 29 | NORTHERN TRUST CORP | 57,70257,702 | $653,186 | 0.40% | ADD 4% |
| 30 | Trexquant Investment LP | 56,20856,208 | $636,275 | 0.39% | NEW |
| 31 | GOLDMAN SACHS GROUP INC | 50,54150,541 | $572,124 | 0.35% | TRIM -3% |
| 32 | RAYMOND JAMES FINANCIAL INC | 42,83842,838 | $484,926 | 0.30% | ADD 86% |
| 33 | BOOTHBAY FUND MANAGEMENT, LLC | 42,00042,000 | $475,440 | 0.29% | NEW |
| 34 | ACADIAN ASSET MANAGEMENT LLC | 41,82541,825 | $471,000 | 0.29% | ADD 24% |
| 35 | VANGUARD FIDUCIARY TRUST CO | 41,54141,541 | $470,244 | 0.29% | NEW |
| 36 | MORGAN STANLEY | 41,12341,123 | $465,512 | 0.29% | TRIM -41% |
| 37 | FMR LLC | 38,90038,900 | $440,348 | 0.27% | ADD 3% |
| 38 | Quantinno Capital Management LP | 35,97835,978 | $407,271 | 0.25% | ADD 30% |
| 39 | MARSHALL WACE, LLP | 34,34334,343 | $388,763 | 0.24% | ADD 74% |
| 40 | CITADEL ADVISORS LLC | 30,91430,914 | $349,946 | 0.21% | TRIM -47% |
| 41 | AIHC Capital Management Ltd | 30,26530,265 | $342,600 | 0.21% | — |
| 42 | Mariner, LLC | 25,81925,819 | $292,145 | 0.18% | NEW |
| 43 | Engineers Gate Manager LP | 23,70223,702 | $268,307 | 0.16% | TRIM -12% |
| 44 | Bank of New York Mellon Corp | 21,73021,730 | $245,980 | 0.15% | ADD 15% |
| 45 | UBS Group AG | 21,67621,676 | $245,372 | 0.15% | ADD 8% |
| 46 | Quadrature Capital Ltd | 20,35620,356 | $230,430 | 0.14% | TRIM -25% |
| 47 | ALGERT GLOBAL LLC | 19,18519,185 | $217,000 | 0.13% | TRIM -29% |
| 48 | Susquehanna Portfolio Strategies, LLC | 19,12519,125 | $216,495 | 0.13% | NEW |
| 49 | GUGGENHEIM CAPITAL LLC | 14,09714,097 | $159,579 | 0.10% | ADD 35% |
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 13,39413,394 | $151,620 | 0.09% | TRIM -18% |
| 51 | IEQ CAPITAL, LLC | 12,77712,777 | $144,636 | 0.09% | NEW |
| 52 | HRT FINANCIAL LP | 10,79010,790 | $122,000 | 0.07% | NEW |
| 53 | DEUTSCHE BANK AG\ | 10,54410,544 | $119,358 | 0.07% | TRIM -17% |
| 54 | RHUMBLINE ADVISERS | 9,8509,850 | $111,495 | 0.07% | TRIM -4% |
| 55 | CWM, LLC | 9,7729,772 | $110,619 | 0.07% | ADD 3293% |
| 56 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 3,2143,214 | $36,382 | 0.02% | ADD 2% |
| 57 | NEW YORK STATE COMMON RETIREMENT FUND | 3,0003,000 | $33,960 | 0.02% | — |
| 58 | WELLS FARGO & COMPANY/MN | 2,5892,589 | $29,307 | 0.02% | TRIM -66% |
| 59 | BNP PARIBAS FINANCIAL MARKETS | 2,3542,354 | $26,647 | 0.02% | ADD 58% |
| 60 | Russell Investments Group, Ltd. | 2,1152,115 | $23,941 | 0.01% | ADD 10% |
| 61 | Vanguard Global Advisers, LLC | 1,9291,929 | $21,836 | 0.01% | NEW |
| 62 | North Star Investment Management Corp. | 1,8001,800 | $20,376 | 0.01% | — |
| 63 | Tower Research Capital LLC (TRC) | 1,6441,644 | $18,610 | 0.01% | ADD 18% |
| 64 | Police & Firemen's Retirement System of New Jersey | 1,3731,373 | $15,542 | 0.01% | — |
| 65 | Essential Partners LLC | 1,3221,322 | $14,965 | 0.01% | NEW |
| 66 | TD Waterhouse Canada Inc. | 808808 | $10,129 | 0.01% | — |
| 67 | PNC FINANCIAL SERVICES GROUP, INC. | 830830 | $9,396 | 0.01% | ADD 12% |
| 68 | GAMMA Investing LLC | 737737 | $8,343 | 0.01% | ADD 623% |
| 69 | Versant Capital Management, Inc | 691691 | $7,822 | 0.00% | NEW |
| 70 | MAI Capital Management | 606606 | $6,860 | 0.00% | ADD 12020% |
| 71 | Ameritas Investment Partners, Inc. | 598598 | $6,769 | 0.00% | — |
| 72 | Legal & General Group Plc | 526526 | $5,954 | 0.00% | — |
| 73 | DUNCKER STREETT & CO INC | 437437 | $4,947 | 0.00% | — |
| 74 | EverSource Wealth Advisors, LLC | 379379 | $4,291 | 0.00% | NEW |
| 75 | CITIGROUP INC | 308308 | $3,487 | 0.00% | TRIM -49% |
| 76 | Allworth Financial LP | 291291 | $3,295 | 0.00% | ADD 29000% |
| 77 | Advisory Services Network, LLC | 245245 | $2,773 | 0.00% | NEW |
| 78 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 225225 | $2,547 | 0.00% | ADD 147% |
| 79 | Sterling Capital Management LLC | 220220 | $2,490 | 0.00% | TRIM -52% |
| 80 | OSAIC HOLDINGS, INC. | 135135 | $1,528 | 0.00% | TRIM -90% |
| 81 | True Wealth Design, LLC | 9999 | $1,121 | 0.00% | NEW |
| 82 | ROYAL BANK OF CANADA | 104104 | $1,000 | 0.00% | TRIM -54% |
| 83 | Arax Advisory Partners | 8686 | $974 | 0.00% | NEW |
| 84 | ROTHSCHILD INVESTMENT LLC | 7272 | $815 | 0.00% | ADD 1100% |
| 85 | Root Financial Partners, LLC | 6363 | $713 | 0.00% | NEW |
| 86 | Keating Financial Advisory Services, Inc. | 6363 | $713 | 0.00% | — |
| 87 | Farther Finance Advisors, LLC | 5454 | $683 | 0.00% | NEW |
| 88 | Optiver Holding B.V. | 6060 | $679 | 0.00% | TRIM -48% |
| 89 | IFP Advisors, Inc | 4545 | $509 | 0.00% | ADD 13% |
| 90 | Wealth Preservation Advisors, LLC | 4444 | $498 | 0.00% | NEW |
| 91 | Bare Financial Services, Inc | 4444 | $498 | 0.00% | NEW |
| 92 | NISA INVESTMENT ADVISORS, LLC | 4040 | $453 | 0.00% | NEW |
| 93 | Fortitude Family Office, LLC | 3939 | $441 | 0.00% | NEW |
| 94 | SJS Investment Consulting Inc. | 2222 | $250 | 0.00% | NEW |
| 95 | Sunbelt Securities, Inc. | 1717 | $192 | 0.00% | ADD 1600% |
| 96 | FIFTH THIRD BANCORP | 1111 | $125 | 0.00% | NEW |
| 97 | JPL Wealth Management, LLC | 22 | $23 | 0.00% | NEW |
| 98 | SBI Securities Co., Ltd. | 11 | $11 | 0.00% | — |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| Lynx1 Capital Management LP | — | — | — | — | 678K | 1.5M | $17M |
| NEA Management Company, LLC | 1.1M | 1.1M | 1.1M | 1.1M | 1.1M | 1.3M | $15M |
| Atlas Venture Life Science Advisors, LLC | 1.1M | 1.1M | 1.1M | 1.1M | 1.1M | 1.1M | $13M |
| Balyasny Asset Management L.P. | 6K | — | — | — | — | 1.0M | $12M |
| Venrock Adviser, LLC | — | — | — | — | — | 1.0M | $11M |
| Affinity Asset Advisors, LLC | — | — | — | — | — | 707K | $8M |
| Nantahala Capital Management, LLC | — | — | — | — | 600K | 660K | $7M |
| ADAR1 Capital Management, LLC | 58K | 69K | 69K | 40K | — | 540K | $6M |
| BlackRock, Inc. | 452K | 441K | 462K | 447K | 457K | 460K | $5M |
| Driehaus Capital Management LLC | 495K | 582K | 581K | 672K | — | 450K | $5M |
| TCG Crossover Management, LLC | — | — | — | 416K | 416K | 416K | $5M |
| Siren, L.L.C. | 419K | 419K | 419K | 419K | 348K | 348K | $4M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 311K | $4M |
| 72 Investment Holdings, LLC | 277K | 277K | 277K | 277K | 277K | 277K | $3M |
| AQR CAPITAL MANAGEMENT LLC | — | — | — | 48K | 41K | 268K | $3M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 98 | 12,801,702 | 88.8% | $145M |
| 2025-Q4 | 83 | 7,561,981 | 52.4% | $61M |
| 2025-Q3 | 92 | 9,963,369 | 69.1% | $475M |
| 2025-Q2 | 71 | 9,058,150 | 62.8% | $115M |
| 2025-Q1 | 75 | 9,704,926 | 67.3% | $169M |
| 2024-Q4 | 84 | 9,447,028 | 65.5% | $360M |
| 2024-Q3 | 71 | 8,549,492 | 59.3% | $286M |
| 2024-Q2 | 63 | 8,439,188 | 58.5% | $286M |
| 2024-Q1 | 49 | 6,938,375 | 48.1% | $621M |
| 2023-Q4 | 40 | 6,570,417 | 45.6% | $302M |
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
“NEA 17 acquired the NEA 17 Shares for investment purposes. Information with respect to the 2026 Private Placement set forth in Item 3 above is incorporated herein by reference to the extent responsive to this Item 4. Subject to the Registration Rights Agreement, the 2024 Registration Rights Agreement and the 2026 Registration Rights Agreement (as defined below) and depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, NEA 17 and ”
| Nantahala Capital Management, LLC | 6.37% | QII | 2025-12-31 | SEC → |
| BlackRock, Inc. | 5.2% | QII | 2026-06-30 | SEC → |
| CITADEL ADVISORS LLC | 3.9% | Passive | 2024-12-31 | SEC → |
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
