$62.36
+1.09 (+1.78%)
USD · as of 2026-08-21 · marketstack
% of shares outstanding suppressed: the summed institutional 13F holdings (34,866,157) exceed the cover-page shares-outstanding count for this quarter (28,589,291, as of 2026-02-05) by more than securities-lending double counting can explain (FINRA short interest 3,681,515 shares at 2026-05-15), so the share count is stale or wrong (common for annual 20-F foreign private issuers after a share issuance) and a percentage would be fabricated. Holder share counts are shown as filed.
| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 3,549,5543.5M | $183M | — | — |
| 2 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,703,2382.7M | $139M | — | ADD 80% |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 2,535,9542.5M | $131M | — | ADD 15% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1,637,1731.6M | $84M | — | NEW |
| 5 | MORGAN STANLEY | 1,450,6341.5M | $75M | — | ADD 15% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 1,266,7381.3M | $65M | — | NEW |
| 7 | D. E. Shaw & Co., Inc. | 1,188,5371.2M | $61M | — | — |
| 8 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,137,3841.1M | $59M | — | TRIM -2% |
| 9 | STATE STREET CORP | 956,011956,011 | $49M | — | ADD 4% |
| 10 | Artisan Partners Limited Partnership | 780,575780,575 | $40M | — | — |
| 11 | BRAIDWELL LP | 677,570677,570 | $35M | — | ADD 25% |
| 12 | GOLDMAN SACHS GROUP INC | 664,003664,003 | $34M | — | ADD 133% |
| 13 | UBS Group AG | 638,928638,928 | $33M | — | ADD 55% |
| 14 | Soleus Capital Management, L.P. | 576,299576,299 | $30M | — | ADD 92% |
| 15 | Vestal Point Capital, LP | 539,269539,269 | $28M | — | NEW |
| 16 | Assenagon Asset Management S.A. | 520,174520,174 | $27M | — | ADD 96% |
| 17 | DEUTSCHE BANK AG\ | 513,175513,175 | $26M | — | — |
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 510,234510,234 | $26M | — | ADD 4% |
| 19 | Aberdeen Group plc | 477,476477,476 | $25M | — | ADD 4% |
| 20 | RENAISSANCE TECHNOLOGIES LLC | 469,968469,968 | $24M | — | ADD 14% |
| 21 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 448,787448,787 | $23M | — | TRIM -3% |
| 22 | ADAR1 Capital Management, LLC | 405,197405,197 | $21M | — | ADD 2601% |
| 23 | CITADEL ADVISORS LLC | 394,076394,076 | $20M | — | TRIM -23% |
| 24 | MILLENNIUM MANAGEMENT LLC | 386,146386,146 | $20M | — | ADD 91% |
| 25 | Walleye Capital LLC | 358,489358,489 | $18M | — | ADD 358% |
| 26 | RA CAPITAL MANAGEMENT, L.P. | 325,663325,663 | $17M | — | ADD 129% |
| 27 | BNP PARIBAS FINANCIAL MARKETS | 319,758319,758 | $16M | — | TRIM -30% |
| 28 | AQR CAPITAL MANAGEMENT LLC | 308,662308,662 | $16M | — | ADD 1042% |
| 29 | Jefferies Financial Group Inc. | 306,423306,423 | $16M | — | — |
| 30 | BAMCO INC /NY/ | 298,470298,470 | $15M | — | TRIM -12% |
| 31 | Amundi | 256,830256,830 | $13M | — | TRIM -30% |
| 32 | ROYAL BANK OF CANADA | 252,971252,971 | $13M | — | ADD 2203% |
| 33 | DIMENSIONAL FUND ADVISORS LP | 234,670234,670 | $12M | — | TRIM -31% |
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 210,573210,573 | $11M | — | ADD 334% |
| 35 | ACADIAN ASSET MANAGEMENT LLC | 209,486209,486 | $11M | — | ADD 795% |
| 36 | NORTHERN TRUST CORP | 197,033197,033 | $10M | — | — |
| 37 | BANK OF AMERICA CORP /DE/ | 186,069186,069 | $10M | — | TRIM -11% |
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 183,351183,351 | $9M | — | TRIM -6% |
| 39 | Cerity Partners LLC | 181,426181,426 | $9M | — | NEW |
| 40 | PRICE T ROWE ASSOCIATES INC /MD/ | 181,313181,313 | $9M | — | TRIM -41% |
| 41 | Bridgewater Associates, LP | 173,533173,533 | $9M | — | ADD 142% |
| 42 | VANGUARD FIDUCIARY TRUST CO | 167,700167,700 | $9M | — | NEW |
| 43 | TUDOR INVESTMENT CORP ET AL | 167,218167,218 | $9M | — | ADD 48% |
| 44 | CANADA PENSION PLAN INVESTMENT BOARD | 164,100164,100 | $8M | — | ADD 56% |
| 45 | Champlain Investment Partners, LLC | 158,989158,989 | $8M | — | TRIM -22% |
| 46 | Y-Intercept (Hong Kong) Ltd | 158,274158,274 | $8M | — | ADD 124% |
| 47 | Balyasny Asset Management L.P. | 151,856151,856 | $8M | — | TRIM -19% |
| 48 | Bank of New York Mellon Corp | 148,764148,764 | $8M | — | TRIM -31% |
| 49 | AMERIPRISE FINANCIAL INC | 143,451143,451 | $7M | — | ADD 57% |
| 50 | Longaeva Partners L.P. | 138,761138,761 | $7M | — | NEW |
| 51 | WASATCH ADVISORS LP | 138,603138,603 | $7M | — | ADD 19% |
| 52 | Regal Partners Ltd | 135,767135,767 | $7M | — | TRIM -36% |
| 53 | LOS ANGELES CAPITAL MANAGEMENT LLC | 132,954132,954 | $7M | — | ADD 94194% |
| 54 | Rock Springs Capital Management LP | 131,800131,800 | $7M | — | — |
| 55 | PRINCIPAL FINANCIAL GROUP INC | 126,788126,788 | $7M | — | — |
| 56 | Trexquant Investment LP | 121,490121,490 | $6M | — | TRIM -43% |
| 57 | Rheos Capital Works Inc. | 117,400117,400 | $6M | — | — |
| 58 | CAPITAL FUND MANAGEMENT S.A. | 109,015109,015 | $6M | — | TRIM -11% |
| 59 | Susquehanna Portfolio Strategies, LLC | 106,157106,157 | $5M | — | ADD 4146% |
| 60 | SG Americas Securities, LLC | 105,147105,147 | $5M | — | ADD 173% |
| 61 | Invesco Ltd. | 103,973103,973 | $5M | — | TRIM -60% |
| 62 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 100,207100,207 | $5M | — | TRIM -47% |
| 63 | Bellevue Group AG | 99,73599,735 | $5M | — | — |
| 64 | Public Sector Pension Investment Board | 93,08693,086 | $5M | — | — |
| 65 | RIVERBRIDGE PARTNERS LLC | 92,49492,494 | $5M | — | TRIM -5% |
| 66 | Gotham Asset Management, LLC | 87,73387,733 | $5M | — | ADD 81% |
| 67 | Nuveen, LLC | 85,16985,169 | $4M | — | TRIM -47% |
| 68 | TWO SIGMA INVESTMENTS, LP | 85,09685,096 | $4M | — | ADD 43% |
| 69 | BROWN CAPITAL MANAGEMENT LLC | 84,36884,368 | $4M | — | TRIM -30% |
| 70 | Edgestream Partners, L.P. | 82,26882,268 | $4M | — | ADD 358% |
| 71 | GLENMEDE TRUST CO NA | 81,49581,495 | $4M | — | — |
| 72 | WORLDQUANT MILLENNIUM ADVISORS LLC | 75,23975,239 | $4M | — | ADD 944% |
| 73 | FIRST TRUST ADVISORS LP | 71,66171,661 | $4M | — | ADD 2233% |
| 74 | NEW YORK STATE COMMON RETIREMENT FUND | 70,88570,885 | $4M | — | ADD 3% |
| 75 | RHUMBLINE ADVISERS | 67,90767,907 | $4M | — | ADD 3% |
| 76 | BARCLAYS PLC | 67,64167,641 | $3M | — | TRIM -21% |
| 77 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 67,28067,280 | $3M | — | ADD 29% |
| 78 | Squarepoint Ops LLC | 66,81466,814 | $3M | — | ADD 879% |
| 79 | Qube Research & Technologies Ltd | 66,18466,184 | $3M | — | NEW |
| 80 | VICTORY CAPITAL MANAGEMENT INC | 64,26064,260 | $3M | — | ADD 468% |
| 81 | Legal & General Group Plc | 61,58361,583 | $3M | — | TRIM -12% |
| 82 | BANK OF NOVA SCOTIA | 60,00060,000 | $3M | — | ADD 50% |
| 83 | Swiss National Bank | 55,50055,500 | $3M | — | — |
| 84 | Man Group plc | 54,48854,488 | $3M | — | ADD 32% |
| 85 | ALGERT GLOBAL LLC | 52,86052,860 | $3M | — | ADD 14% |
| 86 | INTECH INVESTMENT MANAGEMENT LLC | 52,70252,702 | $3M | — | ADD 747% |
| 87 | JPMORGAN CHASE & CO | 53,61553,615 | $3M | — | ADD 18% |
| 88 | Bullseye Asset Management LLC | 51,12851,128 | $3M | — | ADD 42% |
| 89 | FRANKLIN RESOURCES INC | 43,22743,227 | $2M | — | TRIM -81% |
| 90 | SEI INVESTMENTS CO | 42,10042,100 | $2M | — | TRIM -17% |
| 91 | NORDEA INVESTMENT MANAGEMENT AB | 40,42040,420 | $2M | — | ADD 255% |
| 92 | FMR LLC | 37,98437,984 | $2M | — | TRIM -72% |
| 93 | Empowered Funds, LLC | 34,87634,876 | $2M | — | NEW |
| 94 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 34,47334,473 | $2M | — | ADD 32% |
| 95 | Voleon Capital Management LP | 33,12233,122 | $2M | — | TRIM -48% |
| 96 | AXQ CAPITAL, LP | 33,01433,014 | $2M | — | NEW |
| 97 | XTX Topco Ltd | 32,48332,483 | $2M | — | TRIM -29% |
| 98 | CITIGROUP INC | 31,60631,606 | $2M | — | TRIM -9% |
| 99 | ZACKS INVESTMENT MANAGEMENT | 30,02130,021 | $2M | — | NEW |
| 100 | Engineers Gate Manager LP | 29,56729,567 | $2M | — | ADD 54% |
Ranked by each filer’s own reported value, not shares.
2 holders — The filer reported no value for this line, so it carries no dollar figure and is left out of the percentage and value columns.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD PORTFOLIO MANAGEMENT LLC | +1,637,173 | $84M | OPEN |
| VANGUARD CAPITAL MANAGEMENT LLC | +1,266,738 | $65M | OPEN |
| DEERFIELD MANAGEMENT COMPANY, L.P. | +1,197,366 | $62M | ADD |
| Vestal Point Capital, LP | +539,269 | $28M | OPEN |
| ADAR1 Capital Management, LLC | +390,197 | $20M | ADD |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −2,953,170 | $152M | CLOSE |
| FULLER & THALER ASSET MANAGEMENT, INC. | −1,336,198 | $69M | CLOSE |
| JANUS HENDERSON GROUP PLC | −548,880 | $28M | TRIM |
| MARSHALL WACE, LLP | −531,079 | $27M | CLOSE |
| EVENTIDE ASSET MANAGEMENT, LLC | −440,205 | $23M | CLOSE |
Prior quarter split-rebased · 13Fs are long, US-listed only.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 4.2M | 4.0M | 3.9M | 3.5M | 3.6M | 3.5M | $183M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | — | — | 140K | 1.0M | 1.5M | 2.7M | $139M |
| WELLINGTON MANAGEMENT GROUP LLP | 244K | 208K | — | — | 2.2M | 2.5M | $131M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | — | — | — | — | — | 1.6M | $84M |
| MORGAN STANLEY | 585K | 439K | 303K | 451K | 1.3M | 1.5M | $75M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 1.3M | $65M |
| D. E. Shaw & Co., Inc. | 8K | 15K | 14K | 359K | 1.2M | 1.2M | $61M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 903K | 693K | 769K | 1.3M | 1.2M | 1.1M | $59M |
| STATE STREET CORP | 1.1M | 1.0M | 1.0M | 979K | 919K | 956K | $49M |
| Artisan Partners Limited Partnership | 450K | 373K | 362K | 526K | 786K | 781K | $40M |
| BRAIDWELL LP | 293K | 302K | 522K | 884K | 541K | 678K | $35M |
| GOLDMAN SACHS GROUP INC | 33K | 51K | 94K | 263K | 285K | 664K | $34M |
| UBS Group AG | 364K | 485K | 431K | 468K | 411K | 639K | $33M |
| Soleus Capital Management, L.P. | — | 39K | 109K | 728K | 299K | 576K | $30M |
| Vestal Point Capital, LP | — | — | — | 135K | — | 539K | $28M |
Green = added, red = trimmed, grey = held; a dash is a quarter with no 13F on file — a gap, not an exit.
Breaks = no 13F that quarter.
Short interest has its own tab now — open SI →
SEC Form 13F · ~10,250 filers, 10y · long-only, US-listed, filed ≤45d after quarter-end.
SEC Schedule 13D/G XML · group aggregate.