Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-26 | Ezekowitz Alan | Director | −Sell | 18,000 | $3.65 | $65,700 |
| 2026-02-02 | Gould Robert J | Director | −Sell | 15,000 | $10.72 | $160,800 |
| 2026-01-02 | Gould Robert J | Director | −Sell | 15,000 | $11.87 | $178,050 |
| 2026-01-02 | Gould Robert J | Director | −Sell | 15,000 | $10.87 | $163,050 |
| 2025-12-15 | Oltmans Curtis Gale | Officer | −Sell | 3,452 | $12.92 | $44,600 |
| 2025-12-08 | RA Capital Healthcare Fund LP | TenPercentOwner | −Sell | 2,706,397 | $14.28 | $39M |
| 2025-12-08 | RA Capital Healthcare Fund LP | TenPercentOwner | −Sell | 91,722 | $14.98 | $1M |
| 2025-12-08 | RA Capital Healthcare Fund LP | TenPercentOwner | −Sell | 1,377,020 | $13.33 | $18M |
| 2025-11-19 | Gould Robert J | Director | −Sell | 15,000 | $11.03 | $165,450 |
| 2025-05-08 | Tourangeau Greg | Officer | −Sell | 498 | $5.06 | $2,520 |
| 2024-08-21 | Shah Rajeev M. | TenPercentOwner | −Other | 8,500,000 | — | — |
| 2024-07-03 | Sapir Alex | Director,Officer | +Exercise | 150,000 | $3.27 | $490,500 |
| 2024-05-07 | Tourangeau Greg | Officer | −Sell | 236 | $7.76 | $1,831 |
| 2024-03-08 | Tourangeau Greg | Officer | −Sell | 4,884 | $11.72 | $57,240 |
| 2024-03-04 | Sapir Alex | Director,Officer | +Buy | 43,360 | $11.35 | $492,136 |
| 2023-05-10 | Tourangeau Greg | Officer | −Sell | 210 | $3.31 | $695 |
| 2023-01-20 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 1,923,076 | $13.00 | $25M |
| 2023-01-13 | Gould Robert J | Director,Officer | −Sell | 6,766 | $15.00 | $101,490 |
| 2023-01-04 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 122,334 | $7.03 | $860,008 |
| 2023-01-04 | RA Capital Healthcare Fund LP | TenPercentOwner | +Buy | 58,369 | $7.80 | $455,278 |
| 2022-12-27 | Kolchinsky Peter | TenPercentOwner | +Buy | 4,089 | $5.99 | $24,493 |
| 2022-12-19 | Kolchinsky Peter | TenPercentOwner | +Buy | 98,787 | $5.90 | $582,843 |
| 2022-12-16 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 1,341,420 | $5.42 | $7M |
| 2022-12-15 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 237,029 | $5.50 | $1M |
| 2022-12-14 | RA CAPITAL MANAGEMENT, L.P. | TenPercentOwner | +Buy | 824,600 | $5.46 | $5M |
| 2022-12-13 | TRV GP III, LLC | TenPercentOwner | −Other | 2,000,000 | — | — |
| 2022-06-07 | Gould Robert J | Director | +Exercise | 71,435 | $7.84 | $560,050 |
| 2022-06-07 | Gould Robert J | Director | −Sell | 71,435 | $8.09 | $577,909 |
| 2022-06-06 | Gould Robert J | Director | +Exercise | 24,382 | $7.84 | $191,155 |
| 2022-06-06 | Gould Robert J | Director | −Sell | 24,382 | $8.10 | $197,494 |
| 2022-06-03 | Gould Robert J | Director | +Exercise | 25,551 | $7.84 | $200,320 |
| 2022-06-03 | Gould Robert J | Director | −Sell | 25,551 | $7.95 | $203,130 |
| 2022-06-02 | Gould Robert J | Director | +Exercise | 16,689 | $7.84 | $130,842 |
| 2022-06-02 | Gould Robert J | Director | −Sell | 16,689 | $7.92 | $132,177 |
| 2022-05-06 | Tourangeau Greg | Officer | +Grant | 3,250 | — | — |
| 2022-04-07 | Gould Robert J | Director | +Exercise | 5,631 | $7.84 | $44,147 |
| 2022-04-07 | Gould Robert J | Director | −Sell | 5,631 | $24.02 | $135,257 |
| 2022-04-05 | Gould Robert J | Director | +Exercise | 52,552 | $7.84 | $412,008 |
| 2022-04-05 | Gould Robert J | Director | −Sell | 52,552 | $24.26 | $1M |
| 2022-04-04 | Gould Robert J | Director | +Exercise | 7,235 | $7.84 | $56,722 |
| 2022-04-04 | Gould Robert J | Director | −Sell | 7,235 | $24.02 | $173,785 |
| 2022-04-01 | Gould Robert J | Director | −Sell | 34,464 | $24.03 | $828,170 |
| 2022-04-01 | Gould Robert J | Director | +Exercise | 34,464 | $7.84 | $270,198 |
| 2021-12-17 | Oltmans Curtis Gale | Officer | −Gift | 1,088 | — | — |
| 2021-11-10 | STARR KEVIN P | TenPercentOwner | −Other | 1,000,000 | — | — |
| 2021-11-10 | LEVIN MARK J | Director,TenPercentOwner | −Other | 1,000,000 | — | — |
| 2021-09-22 | STARR KEVIN P | TenPercentOwner | −Other | 1,000,000 | — | — |
| 2021-09-22 | LEVIN MARK J | Director,TenPercentOwner | −Other | 1,000,000 | — | — |
| 2021-08-11 | Stuart Bryan | Director,Officer | −Sell | 28,000 | $23.75 | $665,000 |
| 2021-08-11 | Stuart Bryan | Director,Officer | +Exercise | 28,000 | $7.84 | $219,520 |
| 2021-08-10 | Stuart Bryan | Director,Officer | +Exercise | 32,000 | $7.84 | $250,880 |
| 2021-08-10 | Stuart Bryan | Director,Officer | −Sell | 32,000 | $17.50 | $560,000 |
| 2021-08-10 | Moxham Christopher | Officer | +Exercise | 20,714 | $7.84 | $162,398 |
| 2021-08-10 | Moxham Christopher | Officer | −Sell | 20,714 | $17.00 | $352,138 |
| 2021-08-10 | Moxham Christopher | Officer | +Exercise | 31,071 | $7.84 | $243,597 |
| 2021-08-10 | Moxham Christopher | Officer | −Sell | 31,071 | $18.00 | $559,278 |
| 2021-06-28 | GERAGHTY JAMES A | Director | +Buy | 10,000 | $9.16 | $91,600 |
| 2021-06-28 | Oltmans Curtis Gale | Officer | +Buy | 1,088 | $9.01 | $9,803 |
| 2021-06-28 | Thomson Peter G. | Officer | +Buy | 2,300 | $9.00 | $20,700 |
| 2021-06-28 | Morabito Christopher | Officer | +Buy | 1,100 | $9.16 | $10,076 |
| 2021-03-16 | Gould Robert J | Director,Officer | −Sell | 789 | $12.43 | $9,807 |
| 2021-03-15 | Gould Robert J | Director,Officer | −Sell | 9,211 | $12.13 | $111,729 |
| 2021-02-22 | Thomson Peter G. | Officer | −Sell | 5,000 | $14.72 | $73,600 |
| 2021-02-22 | Thomson Peter G. | Officer | +Exercise | 5,000 | $7.84 | $39,200 |
| 2021-02-16 | Gould Robert J | Director,Officer | −Sell | 1,673 | $14.56 | $24,359 |
| 2021-02-16 | Gould Robert J | Director,Officer | −Sell | 6,542 | $14.19 | $92,831 |
| 2021-01-21 | Thomson Peter G. | Officer | −Sell | 6,607 | $14.00 | $92,498 |
| 2021-01-20 | Gould Robert J | Director,Officer | −Sell | 10,000 | $12.08 | $120,800 |
| 2020-09-14 | Wallace Owen B. | Officer | +Exercise | 6,350 | $7.84 | $49,784 |
| 2020-07-08 | Gould Robert J | Director,Officer | −Sell | 2,500 | $20.00 | $50,000 |
| 2020-07-08 | Wallace Owen B. | Officer | −Sell | 2,951 | $20.00 | $59,020 |
| 2020-07-08 | Wallace Owen B. | Officer | +Exercise | 2,951 | $7.84 | $23,136 |
| 2020-07-01 | Cadavid Diego | Officer | −Sell | 1,071 | $18.30 | $19,599 |
| 2020-06-30 | Wallace Owen B. | Officer | +Exercise | 141 | $7.84 | $1,105 |
| 2020-06-30 | Wallace Owen B. | Officer | −Sell | 141 | $20.00 | $2,820 |
| 2020-06-25 | Gould Robert J | Director,Officer | −Sell | 2,500 | $20.80 | $52,000 |
| 2020-06-25 | Cadavid Diego | Officer | +Exercise | 1,459 | $4.83 | $7,047 |
| 2020-06-25 | Cadavid Diego | Officer | −Sell | 1,459 | $22.00 | $32,098 |
| 2020-06-10 | Cadavid Diego | Officer | −Sell | 401 | $22.00 | $8,822 |
| 2020-06-10 | Cadavid Diego | Officer | +Exercise | 401 | $4.83 | $1,937 |
| 2020-06-09 | Gould Robert J | Director,Officer | −Sell | 156 | $20.00 | $3,120 |
| 2020-06-05 | Cadavid Diego | Officer | +Exercise | 451 | $4.83 | $2,178 |
| 2020-06-05 | Cadavid Diego | Officer | −Sell | 451 | $20.18 | $9,101 |
| 2020-06-05 | Gould Robert J | Director,Officer | −Sell | 3,433 | $20.17 | $69,244 |
| 2020-06-04 | Gould Robert J | Director,Officer | −Sell | 1,300 | $20.04 | $26,052 |
| 2020-06-04 | Cadavid Diego | Officer | −Sell | 226 | $20.05 | $4,531 |
| 2020-06-04 | Cadavid Diego | Officer | +Exercise | 226 | $4.83 | $1,092 |
| 2020-06-03 | Cadavid Diego | Officer | +Exercise | 338 | $4.83 | $1,633 |
| 2020-06-03 | Cadavid Diego | Officer | −Sell | 338 | $20.18 | $6,821 |
| 2020-06-03 | Gould Robert J | Director,Officer | −Sell | 1,500 | $20.13 | $30,195 |
| 2020-06-02 | Gould Robert J | Director,Officer | −Sell | 2,797 | $20.00 | $55,940 |
| 2020-06-02 | Cadavid Diego | Officer | +Exercise | 45 | $4.83 | $217 |
| 2020-06-02 | Cadavid Diego | Officer | −Sell | 45 | $20.00 | $900 |
| 2020-06-01 | Gould Robert J | Director,Officer | −Sell | 5 | $20.00 | $100 |
| 2020-05-29 | Gould Robert J | Director,Officer | −Sell | 1,390 | $20.08 | $27,911 |
| 2020-05-29 | Cadavid Diego | Officer | −Sell | 200 | $20.04 | $4,008 |
| 2020-05-29 | Cadavid Diego | Officer | +Exercise | 200 | $4.83 | $966 |
| 2020-05-28 | Wallace Owen B. | Officer | −Sell | 2,232 | $20.00 | $44,640 |
| 2020-05-28 | Wallace Owen B. | Officer | +Exercise | 2,232 | $7.84 | $17,499 |
| 2020-05-28 | Gould Robert J | Director,Officer | −Sell | 1,919 | $20.01 | $38,399 |
| 2020-05-28 | Cadavid Diego | Officer | +Exercise | 600 | $4.83 | $2,898 |
| 2020-05-28 | Cadavid Diego | Officer | −Sell | 600 | $20.00 | $12,000 |
| 2020-05-27 | Wallace Owen B. | Officer | +Exercise | 448 | $7.84 | $3,512 |
| 2020-05-27 | Wallace Owen B. | Officer | −Sell | 448 | $20.00 | $8,960 |
| 2020-05-26 | Gould Robert J | Director,Officer | −Sell | 2,500 | $20.00 | $50,000 |
| 2020-05-26 | Wallace Owen B. | Officer | +Exercise | 412 | $7.84 | $3,230 |
| 2020-05-26 | Wallace Owen B. | Officer | −Sell | 412 | $20.00 | $8,240 |
| 2020-05-12 | Cadavid Diego | Officer | −Sell | 1,860 | $18.00 | $33,480 |
| 2020-05-12 | Cadavid Diego | Officer | +Exercise | 1,860 | $4.83 | $8,984 |
| 2020-05-11 | Thomson Peter G. | Officer | −Sell | 7,500 | $16.00 | $120,000 |
| 2020-03-02 | Cadavid Diego | Officer | −Sell | 315 | $18.13 | $5,711 |
| 2020-03-02 | Cadavid Diego | Officer | −Sell | 1,828 | $17.26 | $31,551 |
| 2020-02-24 | Thomson Peter G. | Officer | −Sell | 2,102 | $17.43 | $36,638 |
| 2020-02-24 | Thomson Peter G. | Officer | −Sell | 2,648 | $16.18 | $42,845 |
| 2020-02-24 | Thomson Peter G. | Officer | −Sell | 250 | $18.61 | $4,653 |
| 2020-02-19 | Wallace Owen B. | Officer | −Sell | 6,088 | $20.00 | $121,760 |
| 2020-02-19 | Wallace Owen B. | Officer | +Exercise | 6,088 | $7.84 | $47,730 |
| 2020-02-19 | Gould Robert J | Director,Officer | −Sell | 2,500 | $20.00 | $50,000 |
| 2020-02-03 | Cadavid Diego | Officer | −Sell | 2,143 | $17.33 | $37,138 |
| 2020-01-23 | Thomson Peter G. | Officer | −Sell | 4,738 | $17.17 | $81,351 |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
