Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-06-17 | Adams Jennifer McKie | Director | −Sell | 50,000 | $32.48 | $2M |
| 2026-06-17 | Adams Jennifer McKie | Director | +Exercise | 50,000 | $3.78 | $189,000 |
| 2026-05-28 | BRYNJELSEN SEAN | Director,Officer | −Sell | 119,852 | $31.88 | $4M |
| 2026-05-28 | BRYNJELSEN SEAN | Director,Officer | −Sell | 148 | $32.67 | $4,835 |
| 2026-05-27 | Krempa David | Officer | −Sell | 19,679 | $31.47 | $619,298 |
| 2026-05-27 | Krempa David | Officer | +Exercise | 7,203 | $3.58 | $25,787 |
| 2026-05-27 | Krempa David | Officer | +Exercise | 12,476 | $1.37 | $17,092 |
| 2026-05-26 | Krempa David | Officer | −Sell | 37,524 | $31.49 | $1M |
| 2026-05-26 | Krempa David | Officer | +Exercise | 12,524 | $1.37 | $17,158 |
| 2026-05-26 | Krempa David | Officer | +Exercise | 25,000 | $1.38 | $34,500 |
| 2026-05-22 | Krempa David | Officer | +Exercise | 30,591 | $3.58 | $109,516 |
| 2026-05-22 | Krempa David | Officer | −Sell | 32,963 | $33.22 | $1M |
| 2026-05-22 | Krempa David | Officer | −Sell | 519 | $35.00 | $18,165 |
| 2026-05-22 | Krempa David | Officer | −Sell | 9,315 | $33.88 | $315,592 |
| 2026-04-21 | RIEDEL NORBERT G | Director | +Exercise | 12,500 | $7.31 | $91,375 |
| 2026-04-21 | RIEDEL NORBERT G | Director | +Exercise | 19,655 | $8.61 | $169,230 |
| 2026-02-03 | RIEDEL NORBERT G | Director | +Exercise | 30,000 | $4.42 | $132,600 |
| 2026-01-14 | Gruber James R. | Officer | −Tax w/h | 2,293 | $15.47 | $35,473 |
| 2026-01-14 | Krempa David | Officer | −Tax w/h | 1,942 | $15.62 | $30,334 |
| 2026-01-01 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Tax w/h | 5,015 | $15.39 | $77,181 |
| 2025-12-12 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Tax w/h | 6,732 | $16.83 | $113,300 |
| 2025-12-12 | Gruber James R. | Officer | −Tax w/h | 4,542 | $16.99 | $77,169 |
| 2025-12-12 | Krempa David | Officer | −Tax w/h | 6,264 | $17.00 | $106,488 |
| 2025-12-12 | Erdogan-Trinkaus Ipek | Officer | −Tax w/h | 85 | $16.90 | $1,436 |
| 2025-08-20 | Gruber James R. | Officer | −Sell | 2,631 | $16.02 | $42,149 |
| 2025-08-19 | Gruber James R. | Officer | −Sell | 39,082 | $16.16 | $631,565 |
| 2025-06-16 | Krempa David | Officer | −Sell | 10,223 | $14.73 | $150,585 |
| 2025-06-13 | Krempa David | Officer | −Sell | 6,800 | $14.77 | $100,436 |
| 2025-06-12 | Krempa David | Officer | −Sell | 16,977 | $14.92 | $253,297 |
| 2025-06-10 | Opaleye Management Inc. | TenPercentOwner | +Buy | 5,000 | $15.82 | $79,100 |
| 2025-06-10 | Opaleye Management Inc. | TenPercentOwner | +Buy | 2,930 | $15.82 | $46,353 |
| 2025-06-05 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Sell | 70,000 | $16.81 | $1M |
| 2025-06-04 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Sell | 70,000 | $17.00 | $1M |
| 2025-06-03 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Sell | 400 | $19.02 | $7,608 |
| 2025-06-03 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Sell | 60,945 | $17.38 | $1M |
| 2025-06-03 | BRYNJELSEN SEAN | Director,Officer,TenPercentOwner | −Sell | 8,655 | $18.38 | $159,079 |
| 2025-01-03 | RIEDEL NORBERT G | Director | +Exercise | 50,000 | $3.78 | $189,000 |
| 2025-01-03 | RIEDEL NORBERT G | Director | +Exercise | 27,400 | $3.58 | $98,092 |
| 2025-01-03 | RIEDEL NORBERT G | Director | +Exercise | 25,000 | $3.47 | $86,750 |
| 2024-10-23 | Opaleye Management Inc. | TenPercentOwner | +Buy | 10,000 | $7.98 | $79,800 |
| 2024-10-08 | Opaleye Management Inc. | TenPercentOwner | +Buy | 30,000 | $7.03 | $210,900 |
| 2024-10-08 | Opaleye Management Inc. | TenPercentOwner | +Buy | 3,970 | $7.03 | $27,909 |
| 2024-10-07 | Opaleye Management Inc. | TenPercentOwner | +Buy | 10,000 | $7.22 | $72,200 |
| 2024-10-07 | Opaleye Management Inc. | TenPercentOwner | +Buy | 1,248 | $7.22 | $9,011 |
| 2024-10-04 | Opaleye Management Inc. | TenPercentOwner | +Buy | 15,000 | $6.77 | $101,550 |
| 2024-10-04 | Opaleye Management Inc. | TenPercentOwner | +Buy | 1,852 | $6.77 | $12,538 |
| 2024-09-11 | Opaleye Management Inc. | TenPercentOwner | +Buy | 45,000 | $4.75 | $213,750 |
| 2024-09-11 | Opaleye Management Inc. | TenPercentOwner | +Buy | 5,000 | $4.75 | $23,750 |
| 2024-09-10 | Opaleye Management Inc. | TenPercentOwner | +Buy | 7,500 | $4.65 | $34,875 |
| 2024-09-10 | Opaleye Management Inc. | TenPercentOwner | +Buy | 50,000 | $4.65 | $232,500 |
| 2022-09-22 | BRYNJELSEN SEAN | Director,Officer | +Buy | 10,000 | $2.10 | $21,000 |
| 2021-11-17 | Opaleye Management Inc. | TenPercentOwner | −Sell | 25,000 | $4.67 | $116,750 |
| 2021-11-16 | Opaleye Management Inc. | TenPercentOwner | −Sell | 11,500 | $4.86 | $55,890 |
| 2021-11-16 | Opaleye Management Inc. | TenPercentOwner | −Sell | 938 | $4.86 | $4,559 |
| 2021-11-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 500 | $4.80 | $2,400 |
| 2021-11-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 2,500 | $4.80 | $12,000 |
| 2021-11-08 | Opaleye Management Inc. | TenPercentOwner | −Sell | 2,661 | $6.10 | $16,232 |
| 2021-11-08 | Opaleye Management Inc. | TenPercentOwner | −Sell | 50,000 | $6.10 | $305,000 |
| 2021-11-05 | Opaleye Management Inc. | TenPercentOwner | −Sell | 159,300 | $6.30 | $1M |
| 2021-11-05 | Opaleye Management Inc. | TenPercentOwner | −Sell | 8,401 | $6.30 | $52,926 |
| 2021-11-04 | Opaleye Management Inc. | TenPercentOwner | −Sell | 81,700 | $6.44 | $526,148 |
| 2021-11-04 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,000 | $6.44 | $25,760 |
| 2021-11-03 | Opaleye Management Inc. | TenPercentOwner | −Sell | 110,000 | $6.53 | $718,300 |
| 2021-11-03 | Opaleye Management Inc. | TenPercentOwner | −Sell | 6,500 | $6.53 | $42,445 |
| 2021-10-12 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,807 | $5.06 | $24,323 |
| 2021-10-12 | Opaleye Management Inc. | TenPercentOwner | −Sell | 82,500 | $5.06 | $417,450 |
| 2021-10-11 | Opaleye Management Inc. | TenPercentOwner | −Sell | 1,601 | $5.01 | $8,021 |
| 2021-10-11 | Opaleye Management Inc. | TenPercentOwner | −Sell | 32,500 | $5.01 | $162,825 |
| 2021-10-08 | Opaleye Management Inc. | TenPercentOwner | −Sell | 2,692 | $5.00 | $13,460 |
| 2021-10-08 | Opaleye Management Inc. | TenPercentOwner | −Sell | 41,000 | $5.00 | $205,000 |
| 2021-08-20 | BRYNJELSEN SEAN | Director,Officer | +Buy | 10,000 | $4.32 | $43,200 |
| 2021-08-20 | Troutman William Wilson | Officer | +Buy | 5,000 | $4.43 | $22,150 |
| 2021-08-06 | Opaleye Management Inc. | TenPercentOwner | −Sell | 330,000 | $5.84 | $2M |
| 2021-08-06 | Opaleye Management Inc. | TenPercentOwner | −Sell | 15,000 | $5.84 | $87,600 |
| 2021-08-05 | Opaleye Management Inc. | TenPercentOwner | −Sell | 5,500 | $5.85 | $32,175 |
| 2021-08-05 | Opaleye Management Inc. | TenPercentOwner | −Sell | 150,000 | $5.85 | $877,500 |
| 2021-08-04 | Opaleye Management Inc. | TenPercentOwner | −Sell | 100,000 | $5.75 | $575,000 |
| 2021-08-04 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,000 | $5.75 | $23,000 |
| 2021-06-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,000 | $8.07 | $32,280 |
| 2021-06-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 101,000 | $8.07 | $815,070 |
| 2021-06-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 101,000 | $8.07 | $815,070 |
| 2021-06-15 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,000 | $8.07 | $32,280 |
| 2021-06-03 | BRYNJELSEN SEAN | Director,Officer | +Buy | 5,000 | $5.96 | $29,800 |
| 2021-05-27 | Opaleye Management Inc. | TenPercentOwner | −Sell | 4,600 | $8.49 | $39,054 |
| 2021-05-27 | Opaleye Management Inc. | TenPercentOwner | −Sell | 121,400 | $8.49 | $1M |
| 2021-05-26 | Opaleye Management Inc. | TenPercentOwner | −Sell | 2,800 | $8.57 | $23,996 |
| 2021-05-26 | Opaleye Management Inc. | TenPercentOwner | −Sell | 65,500 | $8.57 | $561,335 |
| 2021-05-25 | Opaleye Management Inc. | TenPercentOwner | −Sell | 46,000 | $8.53 | $392,380 |
| 2021-05-25 | Opaleye Management Inc. | TenPercentOwner | −Sell | 2,000 | $8.53 | $17,060 |
| 2021-04-12 | HARROW HEALTH, INC. | TenPercentOwner | −Sell | 1,518,000 | $7.00 | $11M |
| 2020-10-16 | Opaleye Management Inc. | TenPercentOwner | +Buy | 385,000 | $7.00 | $3M |
| 2020-10-16 | Opaleye Management Inc. | TenPercentOwner | +Buy | 15,000 | $7.00 | $105,000 |
| 2020-03-19 | CASAMENTO CHARLES J | Director | −Gift | 3,500 | — | — |
| 2019-08-13 | BRYNJELSEN SEAN | Director,Officer | +Buy | 5,000 | $6.15 | $30,750 |
| 2019-08-09 | CASAMENTO CHARLES J | Director | +Buy | 3,500 | $6.11 | $21,385 |
| 2019-05-21 | BRYNJELSEN SEAN | Director,Officer | +Buy | 8,600 | $7.96 | $68,456 |
| 2019-05-20 | BRYNJELSEN SEAN | Director,Officer | +Buy | 1,400 | $7.78 | $10,892 |
| 2018-11-15 | BAUM MARK L | Director | +Buy | 10,000 | $6.00 | $60,000 |
| 2018-11-15 | Troutman William Wilson | Officer | +Buy | 5,000 | $6.00 | $30,000 |
| 2018-11-15 | RIEDEL NORBERT G | Director | +Buy | 5,000 | $6.00 | $30,000 |
| 2018-11-15 | MAIER PAUL V | Director | +Buy | 5,000 | $6.00 | $30,000 |
| 2018-11-15 | BRYNJELSEN SEAN | Director,Officer | +Buy | 10,000 | $6.00 | $60,000 |
| 2018-11-15 | BRYNJELSEN SEAN | Director,Officer | +Conversion | 24,940 | — | — |
| 2018-11-15 | CASAMENTO CHARLES J | Director | +Conversion | 8,675 | — | — |
| 2018-11-15 | CASAMENTO CHARLES J | Director | +Buy | 5,000 | $6.00 | $30,000 |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
