ERAS US Equity

Erasca, Inc.

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Health Care · Pharmaceutical Preparations · CIK 1761918 · FYE 1231

$18.16

-0.71 (-3.76%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding ERAS · 2026-Q1 methodology → sources →

224 holders

% of shares outstanding held

88.0%

Shares held (13F)

273,712,281

Reporting holders

224

Top holders

largest 100 of 224 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Frazier Life Sciences Management, L.P.	24,675,18824.7M	$399M	7.93%	ADD 9%
2	T. Rowe Price Investment Management, Inc.	21,259,64621.3M	$344M	6.84%	—
3	BlackRock, Inc.	20,151,40620.2M	$326M	6.48%	ADD 29%
4	Venrock Adviser, LLC	16,382,81216.4M	$265M	5.27%	TRIM -8%
5	RTW INVESTMENTS, LP	16,157,17516.2M	$261M	5.20%	ADD 10917%
6	Vivo Capital, LLC	12,151,48012.2M	$197M	3.91%	ADD 31%
7	VANGUARD CAPITAL MANAGEMENT LLC	11,249,73811.2M	$182M	3.62%	NEW†
8	Siren, L.L.C.	11,244,24611.2M	$182M	3.62%	ADD 28%
9	Logos Global Management LP	11,150,00011.2M	$180M	3.59%	TRIM -14%
10	Paradigm Biocapital Advisors LP	10,392,70210.4M	$168M	3.34%	TRIM -27%
11	STATE STREET CORP	9,300,0849.3M	$150M	2.99%	ADD 51%
12	ARCH Venture Management, LLC	7,091,5577.1M	$115M	2.28%	TRIM -36%
13	GEODE CAPITAL MANAGEMENT, LLC	5,996,1496.0M	$97M	1.93%	ADD 22%
14	Cormorant Asset Management, LP	5,800,0005.8M	$94M	1.87%	NEW
15	Affinity Asset Advisors, LLC	5,350,0005.3M	$87M	1.72%	ADD 37%
16	Balyasny Asset Management L.P.	5,143,9855.1M	$83M	1.65%	ADD 5145%
17	GOLDMAN SACHS GROUP INC	4,875,1864.9M	$79M	1.57%	ADD 46%
18	JANUS HENDERSON GROUP PLC	3,710,9663.7M	$60M	1.19%	NEW
19	5AM Venture Management, LLC	3,485,9713.5M	$56M	1.12%	TRIM -36%
20	SUVRETTA CAPITAL MANAGEMENT, LLC	3,434,9673.4M	$56M	1.10%	TRIM -76%
21	Commodore Capital LP	3,175,0003.2M	$51M	1.02%	NEW
22	BANK OF AMERICA CORP /DE/	3,055,8973.1M	$49M	0.98%	ADD 90%
23	a16z Capital Management, L.L.C.	2,862,5002.9M	$46M	0.92%	—
24	Woodline Partners LP	2,831,5382.8M	$46M	0.91%	ADD 47%
25	ADAGE CAPITAL PARTNERS GP, L.L.C.	2,100,0002.1M	$34M	0.68%	NEW
26	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,898,2241.9M	$31M	0.61%	ADD 13%
27	SILVERARC CAPITAL MANAGEMENT, LLC	1,851,8121.9M	$30M	0.60%	ADD 41%
28	UBS Group AG	1,848,5801.8M	$30M	0.59%	ADD 984%
29	PRICE T ROWE ASSOCIATES INC /MD/	1,815,3401.8M	$29M	0.58%	ADD 1654%
30	DIMENSIONAL FUND ADVISORS LP	1,786,3891.8M	$29M	0.57%	—
31	VANGUARD PORTFOLIO MANAGEMENT LLC	1,773,7571.8M	$29M	0.57%	NEW
32	NORTHERN TRUST CORP	1,701,6231.7M	$28M	0.55%	ADD 28%
33	VICTORY CAPITAL MANAGEMENT INC	1,654,4971.7M	$27M	0.53%	ADD 8896%
34	VANGUARD FIDUCIARY TRUST CO	1,537,9151.5M	$25M	0.49%	NEW
35	FMR LLC	1,490,0801.5M	$24M	0.48%	ADD 186%
36	RENAISSANCE TECHNOLOGIES LLC	1,398,8691.4M	$23M	0.45%	ADD 65%
37	D. E. Shaw & Co., Inc.	1,219,5341.2M	$20M	0.39%	ADD 504%
38	Rock Springs Capital Management LP	1,103,4691.1M	$18M	0.35%	ADD 16%
39	BNP PARIBAS FINANCIAL MARKETS	1,087,3011.1M	$18M	0.35%	ADD 3247%
40	MORGAN STANLEY	989,210989,210	$16M	0.32%	ADD 22%
41	EcoR1 Capital, LLC	900,000900,000	$15M	0.29%	NEW
42	First Turn Management, LLC	867,639867,639	$14M	0.28%	NEW
43	JPMORGAN CHASE & CO	924,405924,405	$14M	0.30%	TRIM -20%
44	Holocene Advisors, LP	760,722760,722	$12M	0.24%	NEW
45	Invesco Ltd.	759,932759,932	$12M	0.24%	ADD 130%
46	Integral Health Asset Management, LLC	700,000700,000	$11M	0.23%	NEW
47	Point72 Asset Management, L.P.	693,309693,309	$11M	0.22%	NEW
48	AQR CAPITAL MANAGEMENT LLC	691,205691,205	$11M	0.22%	ADD 3%
49	AMERIPRISE FINANCIAL INC	670,597670,597	$11M	0.22%	NEW
50	ALLIANCEBERNSTEIN L.P.	2,644,9202.6M	$10M	0.85%	ADD 1167%
51	WELLINGTON MANAGEMENT GROUP LLP	595,379595,379	$10M	0.19%	ADD 10%
52	MILLENNIUM MANAGEMENT LLC	575,996575,996	$9M	0.19%	TRIM -74%
53	ExodusPoint Capital Management, LP	575,715575,715	$9M	0.19%	TRIM -61%
54	Bank of New York Mellon Corp	559,629559,629	$9M	0.18%	ADD 2%
55	Nuveen, LLC	543,021543,021	$9M	0.17%	ADD 28%
56	Ensign Peak Advisors, Inc	500,723500,723	$8M	0.16%	NEW
57	CITADEL ADVISORS LLC	498,381498,381	$8M	0.16%	TRIM -52%
58	STEMPOINT CAPITAL LP	479,722479,722	$8M	0.15%	NEW
59	JANE STREET GROUP, LLC	455,019455,019	$7M	0.15%	TRIM -50%
60	MARSHALL WACE, LLP	426,526426,526	$7M	0.14%	ADD 588%
61	Spruce Street Capital LP	422,543422,543	$7M	0.14%	TRIM -89%
62	Creative Planning	418,834418,834	$7M	0.13%	ADD 10%
63	PRUDENTIAL FINANCIAL INC	416,715416,715	$7M	0.13%	ADD 3167%
64	Parkman Healthcare Partners LLC	406,702406,702	$7M	0.13%	NEW
65	TD Asset Management Inc	394,260394,260	$6M	0.13%	ADD 72%
66	AMERICAN CENTURY COMPANIES INC	380,977380,977	$6M	0.12%	ADD 130%
67	Polymer Capital Management (HK) LTD	357,670357,670	$6M	0.12%	NEW
68	ACUTA CAPITAL PARTNERS, LLC	354,575354,575	$6M	0.11%	NEW
69	Atom Investors LP	345,587345,587	$6M	0.11%	NEW
70	KVP Capital Advisors, LP	340,000340,000	$6M	0.11%	NEW
71	Swiss National Bank	336,800336,800	$5M	0.11%	NEW
72	Trexquant Investment LP	301,066301,066	$5M	0.10%	NEW
73	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	259,007259,007	$4M	0.08%	NEW
74	VOYA INVESTMENT MANAGEMENT LLC	253,554253,554	$4M	0.08%	ADD 664%
75	SIMPLEX TRADING, LLC	252,747252,747	$4M	0.08%	TRIM -27%
76	Rafferty Asset Management, LLC	251,963251,963	$4M	0.08%	ADD 92%
77	RHUMBLINE ADVISERS	242,636242,636	$4M	0.08%	ADD 28%
78	FRED ALGER MANAGEMENT, LLC	236,824236,824	$4M	0.08%	NEW
79	Tidal Investments LLC	226,877226,877	$4M	0.07%	NEW
80	Tema ETFs LLC	226,877226,877	$4M	0.07%	NEW
81	Seven Fleet Capital Management LP	222,468222,468	$4M	0.07%	NEW
82	MANUFACTURERS LIFE INSURANCE COMPANY, THE	216,614216,614	$4M	0.07%	ADD 296%
83	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	204,449204,449	$3M	0.07%	ADD 1813%
84	TANG CAPITAL MANAGEMENT LLC	200,000200,000	$3M	0.06%	TRIM -78%
85	Pictet Asset Management Holding SA	208,273208,273	$3M	0.07%	NEW
86	HighVista Strategies LLC	181,069181,069	$3M	0.06%	NEW
87	Cinctive Capital Management LP	171,920171,920	$3M	0.06%	NEW
88	Longaeva Partners L.P.	171,233171,233	$3M	0.06%	NEW
89	DEUTSCHE BANK AG\	163,326163,326	$3M	0.05%	ADD 34%
90	NATIXIS	163,192163,192	$3M	0.05%	NEW
91	SUSQUEHANNA INTERNATIONAL GROUP, LLP	153,647153,647	$2M	0.05%	TRIM -23%
92	XTX Topco Ltd	147,618147,618	$2M	0.05%	ADD 1267%
93	Informed Momentum Co LLC	137,925137,925	$2M	0.04%	NEW
94	Legal & General Group Plc	133,444133,444	$2M	0.04%	ADD 765%
95	Vanguard Global Advisers, LLC	113,645113,645	$2M	0.04%	NEW
96	PROFUND ADVISORS LLC	113,216113,216	$2M	0.04%	ADD 124%
97	VANGUARD ASSET MANAGEMENT, Ltd	111,757111,757	$2M	0.04%	NEW
98	WELLS FARGO & COMPANY/MN	107,176107,176	$2M	0.03%	TRIM -51%
99	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	106,830106,830	$2M	0.03%	ADD 21%
100	MetLife Investment Management, LLC	103,644103,644	$2M	0.03%	ADD 29%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Frazier Life Sciences Management, L.P.

19.4M

22.6M

22.7M

24.7M

$399M

T. Rowe Price Investment Management, Inc.

16.7M

17.3M

20.3M

20.2M

20.9M

21.3M

$344M

BlackRock, Inc.

15.8M

15.6M

15.2M

15.1M

15.6M

20.2M

$326M

Venrock Adviser, LLC

16.2M

17.9M

16.4M

$265M

RTW INVESTMENTS, LP

—

147K

16.2M

$261M

Vivo Capital, LLC

6.8M

9.3M

12.2M

$197M

VANGUARD CAPITAL MANAGEMENT LLC

—

11.2M

$182M

Siren, L.L.C.

8.9M

8.8M

11.2M

$182M

Logos Global Management LP

12.5M

13.0M

15.0M

15.2M

13.0M

11.2M

$180M

Paradigm Biocapital Advisors LP

10.8M

11.9M

13.6M

14.2M

10.4M

$168M

STATE STREET CORP

6.6M

4.2M

4.0M

6.2M

9.3M

$150M

ARCH Venture Management, LLC

11.1M

7.1M

$115M

GEODE CAPITAL MANAGEMENT, LLC

4.6M

4.8M

4.9M

6.0M

$97M

Cormorant Asset Management, LP

—

5.8M

$94M

Affinity Asset Advisors, LLC

2.5M

3.3M

4.1M

4.3M

3.9M

5.3M

$87M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	224	273,712,281	88.0%	$4.4B
2025-Q4	154	224,062,864	72.0%	$834M
2025-Q3	141	216,178,958	69.5%	$471M
2025-Q2	142	218,715,250	70.3%	$278M
2025-Q1	154	224,328,565	72.1%	$307M
2024-Q4	146	230,889,201	74.2%	$580M
2024-Q3	132	234,063,980	75.3%	$639M
2024-Q2	125	211,505,090	68.0%	$499M
2024-Q1	108	74,064,409	23.8%	$153M
2023-Q4	119	70,027,167	22.5%	$149M
2023-Q3	109	71,305,182

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · ERAS

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
T. Rowe Price Investment Management, Inc.	6.8%	QII	2026-03-31	SEC →
Venrock Healthcare Capital Partners III, L.P.	5.3%	Passive	2026-03-31	SEC →
Frazier Life Sciences Public Fund, L.P.	5.3%	Passive	2025-06-30	SEC →
RTW INVESTMENTS, LP	5.2%	QII	2026-03-31	SEC →
Logos Global Management LP	4.8%

Institutional ownership· 13F filers holding ERAS · 2026-Q1 methodology → sources →

224 holders

% of shares outstanding held

88.0%

Shares held (13F)

273,712,281

Reporting holders

224

Top holders

largest 100 of 224 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Frazier Life Sciences Management, L.P.	24,675,18824.7M	$399M	7.93%	ADD 9%
2	T. Rowe Price Investment Management, Inc.	21,259,64621.3M	$344M	6.84%	—
3	BlackRock, Inc.	20,151,40620.2M	$326M	6.48%	ADD 29%
4	Venrock Adviser, LLC	16,382,81216.4M	$265M	5.27%	TRIM -8%
5	RTW INVESTMENTS, LP	16,157,17516.2M	$261M	5.20%	ADD 10917%
6	Vivo Capital, LLC	12,151,48012.2M	$197M	3.91%	ADD 31%
7	VANGUARD CAPITAL MANAGEMENT LLC	11,249,73811.2M	$182M	3.62%	NEW†
8	Siren, L.L.C.	11,244,24611.2M	$182M	3.62%	ADD 28%
9	Logos Global Management LP	11,150,00011.2M	$180M	3.59%	TRIM -14%
10	Paradigm Biocapital Advisors LP	10,392,70210.4M	$168M	3.34%	TRIM -27%
11	STATE STREET CORP	9,300,0849.3M	$150M	2.99%	ADD 51%
12	ARCH Venture Management, LLC	7,091,5577.1M	$115M	2.28%	TRIM -36%
13	GEODE CAPITAL MANAGEMENT, LLC	5,996,1496.0M	$97M	1.93%	ADD 22%
14	Cormorant Asset Management, LP	5,800,0005.8M	$94M	1.87%	NEW
15	Affinity Asset Advisors, LLC	5,350,0005.3M	$87M	1.72%	ADD 37%
16	Balyasny Asset Management L.P.	5,143,9855.1M	$83M	1.65%	ADD 5145%
17	GOLDMAN SACHS GROUP INC	4,875,1864.9M	$79M	1.57%	ADD 46%
18	JANUS HENDERSON GROUP PLC	3,710,9663.7M	$60M	1.19%	NEW
19	5AM Venture Management, LLC	3,485,9713.5M	$56M	1.12%	TRIM -36%
20	SUVRETTA CAPITAL MANAGEMENT, LLC	3,434,9673.4M	$56M	1.10%	TRIM -76%
21	Commodore Capital LP	3,175,0003.2M	$51M	1.02%	NEW
22	BANK OF AMERICA CORP /DE/	3,055,8973.1M	$49M	0.98%	ADD 90%
23	a16z Capital Management, L.L.C.	2,862,5002.9M	$46M	0.92%	—
24	Woodline Partners LP	2,831,5382.8M	$46M	0.91%	ADD 47%
25	ADAGE CAPITAL PARTNERS GP, L.L.C.	2,100,0002.1M	$34M	0.68%	NEW
26	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,898,2241.9M	$31M	0.61%	ADD 13%
27	SILVERARC CAPITAL MANAGEMENT, LLC	1,851,8121.9M	$30M	0.60%	ADD 41%
28	UBS Group AG	1,848,5801.8M	$30M	0.59%	ADD 984%
29	PRICE T ROWE ASSOCIATES INC /MD/	1,815,3401.8M	$29M	0.58%	ADD 1654%
30	DIMENSIONAL FUND ADVISORS LP	1,786,3891.8M	$29M	0.57%	—
31	VANGUARD PORTFOLIO MANAGEMENT LLC	1,773,7571.8M	$29M	0.57%	NEW
32	NORTHERN TRUST CORP	1,701,6231.7M	$28M	0.55%	ADD 28%
33	VICTORY CAPITAL MANAGEMENT INC	1,654,4971.7M	$27M	0.53%	ADD 8896%
34	VANGUARD FIDUCIARY TRUST CO	1,537,9151.5M	$25M	0.49%	NEW
35	FMR LLC	1,490,0801.5M	$24M	0.48%	ADD 186%
36	RENAISSANCE TECHNOLOGIES LLC	1,398,8691.4M	$23M	0.45%	ADD 65%
37	D. E. Shaw & Co., Inc.	1,219,5341.2M	$20M	0.39%	ADD 504%
38	Rock Springs Capital Management LP	1,103,4691.1M	$18M	0.35%	ADD 16%
39	BNP PARIBAS FINANCIAL MARKETS	1,087,3011.1M	$18M	0.35%	ADD 3247%
40	MORGAN STANLEY	989,210989,210	$16M	0.32%	ADD 22%
41	EcoR1 Capital, LLC	900,000900,000	$15M	0.29%	NEW
42	First Turn Management, LLC	867,639867,639	$14M	0.28%	NEW
43	JPMORGAN CHASE & CO	924,405924,405	$14M	0.30%	TRIM -20%
44	Holocene Advisors, LP	760,722760,722	$12M	0.24%	NEW
45	Invesco Ltd.	759,932759,932	$12M	0.24%	ADD 130%
46	Integral Health Asset Management, LLC	700,000700,000	$11M	0.23%	NEW
47	Point72 Asset Management, L.P.	693,309693,309	$11M	0.22%	NEW
48	AQR CAPITAL MANAGEMENT LLC	691,205691,205	$11M	0.22%	ADD 3%
49	AMERIPRISE FINANCIAL INC	670,597670,597	$11M	0.22%	NEW
50	ALLIANCEBERNSTEIN L.P.	2,644,9202.6M	$10M	0.85%	ADD 1167%
51	WELLINGTON MANAGEMENT GROUP LLP	595,379595,379	$10M	0.19%	ADD 10%
52	MILLENNIUM MANAGEMENT LLC	575,996575,996	$9M	0.19%	TRIM -74%
53	ExodusPoint Capital Management, LP	575,715575,715	$9M	0.19%	TRIM -61%
54	Bank of New York Mellon Corp	559,629559,629	$9M	0.18%	ADD 2%
55	Nuveen, LLC	543,021543,021	$9M	0.17%	ADD 28%
56	Ensign Peak Advisors, Inc	500,723500,723	$8M	0.16%	NEW
57	CITADEL ADVISORS LLC	498,381498,381	$8M	0.16%	TRIM -52%
58	STEMPOINT CAPITAL LP	479,722479,722	$8M	0.15%	NEW
59	JANE STREET GROUP, LLC	455,019455,019	$7M	0.15%	TRIM -50%
60	MARSHALL WACE, LLP	426,526426,526	$7M	0.14%	ADD 588%
61	Spruce Street Capital LP	422,543422,543	$7M	0.14%	TRIM -89%
62	Creative Planning	418,834418,834	$7M	0.13%	ADD 10%
63	PRUDENTIAL FINANCIAL INC	416,715416,715	$7M	0.13%	ADD 3167%
64	Parkman Healthcare Partners LLC	406,702406,702	$7M	0.13%	NEW
65	TD Asset Management Inc	394,260394,260	$6M	0.13%	ADD 72%
66	AMERICAN CENTURY COMPANIES INC	380,977380,977	$6M	0.12%	ADD 130%
67	Polymer Capital Management (HK) LTD	357,670357,670	$6M	0.12%	NEW
68	ACUTA CAPITAL PARTNERS, LLC	354,575354,575	$6M	0.11%	NEW
69	Atom Investors LP	345,587345,587	$6M	0.11%	NEW
70	KVP Capital Advisors, LP	340,000340,000	$6M	0.11%	NEW
71	Swiss National Bank	336,800336,800	$5M	0.11%	NEW
72	Trexquant Investment LP	301,066301,066	$5M	0.10%	NEW
73	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	259,007259,007	$4M	0.08%	NEW
74	VOYA INVESTMENT MANAGEMENT LLC	253,554253,554	$4M	0.08%	ADD 664%
75	SIMPLEX TRADING, LLC	252,747252,747	$4M	0.08%	TRIM -27%
76	Rafferty Asset Management, LLC	251,963251,963	$4M	0.08%	ADD 92%
77	RHUMBLINE ADVISERS	242,636242,636	$4M	0.08%	ADD 28%
78	FRED ALGER MANAGEMENT, LLC	236,824236,824	$4M	0.08%	NEW
79	Tidal Investments LLC	226,877226,877	$4M	0.07%	NEW
80	Tema ETFs LLC	226,877226,877	$4M	0.07%	NEW
81	Seven Fleet Capital Management LP	222,468222,468	$4M	0.07%	NEW
82	MANUFACTURERS LIFE INSURANCE COMPANY, THE	216,614216,614	$4M	0.07%	ADD 296%
83	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	204,449204,449	$3M	0.07%	ADD 1813%
84	TANG CAPITAL MANAGEMENT LLC	200,000200,000	$3M	0.06%	TRIM -78%
85	Pictet Asset Management Holding SA	208,273208,273	$3M	0.07%	NEW
86	HighVista Strategies LLC	181,069181,069	$3M	0.06%	NEW
87	Cinctive Capital Management LP	171,920171,920	$3M	0.06%	NEW
88	Longaeva Partners L.P.	171,233171,233	$3M	0.06%	NEW
89	DEUTSCHE BANK AG\	163,326163,326	$3M	0.05%	ADD 34%
90	NATIXIS	163,192163,192	$3M	0.05%	NEW
91	SUSQUEHANNA INTERNATIONAL GROUP, LLP	153,647153,647	$2M	0.05%	TRIM -23%
92	XTX Topco Ltd	147,618147,618	$2M	0.05%	ADD 1267%
93	Informed Momentum Co LLC	137,925137,925	$2M	0.04%	NEW
94	Legal & General Group Plc	133,444133,444	$2M	0.04%	ADD 765%
95	Vanguard Global Advisers, LLC	113,645113,645	$2M	0.04%	NEW
96	PROFUND ADVISORS LLC	113,216113,216	$2M	0.04%	ADD 124%
97	VANGUARD ASSET MANAGEMENT, Ltd	111,757111,757	$2M	0.04%	NEW
98	WELLS FARGO & COMPANY/MN	107,176107,176	$2M	0.03%	TRIM -51%
99	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	106,830106,830	$2M	0.03%	ADD 21%
100	MetLife Investment Management, LLC	103,644103,644	$2M	0.03%	ADD 29%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Frazier Life Sciences Management, L.P.

19.4M

22.6M

22.7M

24.7M

$399M

T. Rowe Price Investment Management, Inc.

16.7M

17.3M

20.3M

20.2M

20.9M

21.3M

$344M

BlackRock, Inc.

15.8M

15.6M

15.2M

15.1M

15.6M

20.2M

$326M

Venrock Adviser, LLC

16.2M

17.9M

16.4M

$265M

RTW INVESTMENTS, LP

—

147K

16.2M

$261M

Vivo Capital, LLC

6.8M

9.3M

12.2M

$197M

VANGUARD CAPITAL MANAGEMENT LLC

—

11.2M

$182M

Siren, L.L.C.

8.9M

8.8M

11.2M

$182M

Logos Global Management LP

12.5M

13.0M

15.0M

15.2M

13.0M

11.2M

$180M

Paradigm Biocapital Advisors LP

10.8M

11.9M

13.6M

14.2M

10.4M

$168M

STATE STREET CORP

6.6M

4.2M

4.0M

6.2M

9.3M

$150M

ARCH Venture Management, LLC

11.1M

7.1M

$115M

GEODE CAPITAL MANAGEMENT, LLC

4.6M

4.8M

4.9M

6.0M

$97M

Cormorant Asset Management, LP

—

5.8M

$94M

Affinity Asset Advisors, LLC

2.5M

3.3M

4.1M

4.3M

3.9M

5.3M

$87M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	224	273,712,281	88.0%	$4.4B
2025-Q4	154	224,062,864	72.0%	$834M
2025-Q3	141	216,178,958	69.5%	$471M
2025-Q2	142	218,715,250	70.3%	$278M
2025-Q1	154	224,328,565	72.1%	$307M
2024-Q4	146	230,889,201	74.2%	$580M
2024-Q3	132	234,063,980	75.3%	$639M
2024-Q2	125	211,505,090	68.0%	$499M
2024-Q1	108	74,064,409	23.8%	$153M
2023-Q4	119	70,027,167	22.5%	$149M
2023-Q3	109	71,305,182

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · ERAS

Large holders — 13G, passive (top 5 of 8 by % of class)

Holder	% of class	Type	As of
T. Rowe Price Investment Management, Inc.	6.8%	QII	2026-03-31	SEC →
Venrock Healthcare Capital Partners III, L.P.	5.3%	Passive	2026-03-31	SEC →
Frazier Life Sciences Public Fund, L.P.	5.3%	Passive	2025-06-30	SEC →
RTW INVESTMENTS, LP	5.2%	QII	2026-03-31	SEC →
Logos Global Management LP	4.8%

ERAS US Equity☆

Institutional ownership· 13F filers holding ERAS · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · ERAS

Institutional ownership· 13F filers holding ERAS · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · ERAS

ERAS US Equity