| # | Holder | Shares | Value | % of shares out | Δ QoQ |
|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 10,365,07410.4M | $18M | 6.92% | — |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 5,452,7625.5M | $9M | 3.64% | NEW† |
| 3 | SAMSARA BIOCAPITAL, LLC | 3,428,5713.4M | $6M | 2.29% | NEW† |
| 4 | GEODE CAPITAL MANAGEMENT, LLC | 3,121,5783.1M | $5M | 2.08% | ADD 14% |
| 5 | Kohlberg Kravis Roberts & Co. L.P. | 3,036,0763.0M | $5M | 2.03% | — |
| 6 | STATE STREET CORP | 2,325,8592.3M | $4M | 1.55% | ADD 5% |
| 7 | TWO SIGMA INVESTMENTS, LP | 2,302,0012.3M | $4M | 1.54% | ADD 357% |
| 8 | Alyeska Investment Group, L.P. | 2,250,0002.3M | $4M | 1.50% | NEW |
| 9 | CM Management, LLC | 2,100,0002.1M | $4M | 1.40% | — |
| 10 | C WorldWide Group Holding A/S | 1,928,4641.9M | $3M | 1.29% | — |
| 11 | TANG CAPITAL MANAGEMENT LLC | 1,886,7481.9M | $3M | 1.26% | TRIM -31% |
| 12 | Hudson Bay Capital Management LP | 1,704,9801.7M | $3M | 1.14% | ADD 104% |
| 13 | PANAGORA ASSET MANAGEMENT INC | 1,459,3101.5M | $2M | 0.97% | TRIM -10% |
| 14 | Propel Bio Management, LLC | 1,420,5501.4M | $2M | 0.95% | NEW |
| 15 | AQR CAPITAL MANAGEMENT LLC | 1,206,0461.2M | $2M | 0.80% | ADD 36% |
| 16 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,155,9011.2M | $2M | 0.77% | ADD 24% |
| 17 | VANGUARD FIDUCIARY TRUST CO | 949,919949,919 | $2M | 0.63% | NEW |
| 18 | NORTHERN TRUST CORP | 913,800913,800 | $2M | 0.61% | ADD 15% |
| 19 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 899,999899,999 | $2M | 0.60% | — |
| 20 | GOLDMAN SACHS GROUP INC | 696,158696,158 | $1M | 0.46% | ADD 127% |
| 21 | VANGUARD PORTFOLIO MANAGEMENT LLC | 604,525604,525 | $1M | 0.40% | NEW |
| 22 | UBS Group AG | 547,209547,209 | $924,783 | 0.37% | TRIM -10% |
| 23 | SEI INVESTMENTS CO | 453,763453,763 | $766,859 | 0.30% | ADD 492% |
| 24 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 441,000441,000 | $745,290 | 0.29% | — |
| 25 | Invesco Ltd. | 335,309335,309 | $566,672 | 0.22% | TRIM -12% |
| 26 | RENAISSANCE TECHNOLOGIES LLC | 331,700331,700 | $560,573 | 0.22% | ADD 141% |
| 27 | BANK OF AMERICA CORP /DE/ | 324,133324,133 | $547,786 | 0.22% | ADD 190% |
| 28 | STRS OHIO | 324,000324,000 | $547,560 | 0.22% | — |
| 29 | GSA CAPITAL PARTNERS LLP | 319,655319,655 | $540,000 | 0.21% | TRIM -33% |
| 30 | MILLENNIUM MANAGEMENT LLC | 311,986311,986 | $527,256 | 0.21% | TRIM -53% |
| 31 | Informed Momentum Co LLC | 309,801309,801 | $523,564 | 0.21% | NEW |
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 287,500287,500 | $485,875 | 0.19% | TRIM -25% |
| 33 | Bank of New York Mellon Corp | 285,033285,033 | $481,706 | 0.19% | TRIM -2% |
| 34 | MARSHALL WACE, LLP | 270,087270,087 | $456,447 | 0.18% | ADD 216% |
| 35 | Simplify Asset Management Inc. | 253,140253,140 | $427,807 | 0.17% | NEW |
| 36 | Jefferies Financial Group Inc. | 252,000252,000 | $425,880 | 0.17% | TRIM -36% |
| 37 | Tyche Wealth Partners LLC | 240,868240,868 | $407,067 | 0.16% | ADD 9% |
| 38 | CITADEL ADVISORS LLC | 233,946233,946 | $395,369 | 0.16% | NEW |
| 39 | Nuveen, LLC | 210,379210,379 | $355,541 | 0.14% | — |
| 40 | MORGAN STANLEY | 197,511197,511 | $333,793 | 0.13% | TRIM -20% |
| 41 | BARCLAYS PLC | 195,473195,473 | $330,350 | 0.13% | TRIM -43% |
| 42 | Squarepoint Ops LLC | 194,405194,405 | $328,544 | 0.13% | ADD 110% |
| 43 | ALLIANCEBERNSTEIN L.P. | 213,590213,590 | $303,298 | 0.14% | — |
| 44 | DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 159,990159,990 | $270,383 | 0.11% | NEW |
| 45 | ENVESTNET ASSET MANAGEMENT INC | 152,194152,194 | $257,208 | 0.10% | NEW |
| 46 | RHUMBLINE ADVISERS | 125,101125,101 | $211,410 | 0.08% | TRIM -5% |
| 47 | IEQ CAPITAL, LLC | 121,967121,967 | $206,124 | 0.08% | ADD 54% |
| 48 | LPL Financial LLC | 120,796120,796 | $204,145 | 0.08% | ADD 23% |
| 49 | ACADIAN ASSET MANAGEMENT LLC | 117,866117,866 | $198,000 | 0.08% | ADD 128% |
| 50 | Summit Financial, LLC | 112,088112,088 | $189,429 | 0.07% | NEW |
| 51 | GROUP ONE TRADING LLC | 111,791111,791 | $188,927 | 0.07% | ADD 171% |
| 52 | Shay Capital LLC | 105,326105,326 | $178,001 | 0.07% | NEW |
| 53 | Headlands Technologies LLC | 100,272100,272 | $169,460 | 0.07% | NEW |
| 54 | Corient Private Wealth LLC | 100,002100,002 | $169,004 | 0.07% | TRIM -44% |
| 55 | HSBC HOLDINGS PLC | 91,89591,895 | $158,059 | 0.06% | TRIM -51% |
| 56 | Dauntless Investment Group, LLC | 76,08776,087 | $128,587 | 0.05% | NEW |
| 57 | DEUTSCHE BANK AG\ | 71,76271,762 | $121,277 | 0.05% | — |
| 58 | PRICE T ROWE ASSOCIATES INC /MD/ | 71,53671,536 | $121,000 | 0.05% | ADD 20% |
| 59 | CWM, LLC | 70,34170,341 | $118,876 | 0.05% | ADD 74% |
| 60 | XTX Topco Ltd | 69,80969,809 | $117,977 | 0.05% | TRIM -58% |
| 61 | SteelPeak Wealth, LLC | 69,00069,000 | $116,610 | 0.05% | — |
| 62 | Vanguard Global Advisers, LLC | 57,80957,809 | $97,697 | 0.04% | NEW |
| 63 | WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 53,57153,571 | $92,678 | 0.04% | ADD 59% |
| 64 | CITIGROUP INC | 52,33352,333 | $88,443 | 0.03% | TRIM -73% |
| 65 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 50,44550,445 | $85,252 | 0.03% | ADD 2% |
| 66 | JPMORGAN CHASE & CO | 53,15653,156 | $85,050 | 0.04% | ADD 4% |
| 67 | SIMPLEX TRADING, LLC | 44,40244,402 | $75,039 | 0.03% | TRIM -8% |
| 68 | Cambridge Investment Research Advisors, Inc. | 43,57643,576 | $74,000 | 0.03% | — |
| 69 | INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 42,40842,408 | $73,790 | 0.03% | TRIM -5% |
| 70 | AMERICAN CENTURY COMPANIES INC | 43,24243,242 | $73,079 | 0.03% | NEW |
| 71 | JANE STREET GROUP, LLC | 40,49440,494 | $68,435 | 0.03% | TRIM -93% |
| 72 | MetLife Investment Management, LLC | 39,01339,013 | $65,932 | 0.03% | NEW |
| 73 | WELLS FARGO & COMPANY/MN | 38,63938,639 | $65,300 | 0.03% | TRIM -67% |
| 74 | Diversified Trust Co | 38,47138,471 | $65,015 | 0.03% | ADD 37% |
| 75 | Atria Investments, Inc | 37,39137,391 | $63,191 | 0.02% | NEW |
| 76 | Cerity Partners LLC | 35,96835,968 | $60,786 | 0.02% | ADD 117% |
| 77 | DIMENSIONAL FUND ADVISORS LP | 35,39735,397 | $59,821 | 0.02% | NEW |
| 78 | Carr Financial Group Corp | 35,19535,195 | $59,480 | 0.02% | — |
| 79 | Vanguard Personalized Indexing Management, LLC | 33,40633,406 | $56,456 | 0.02% | TRIM -4% |
| 80 | SG Americas Securities, LLC | 32,79732,797 | $55,000 | 0.02% | TRIM -5% |
| 81 | Cetera Investment Advisers | 31,68531,685 | $53,548 | 0.02% | NEW |
| 82 | Police & Firemen's Retirement System of New Jersey | 28,23028,230 | $47,709 | 0.02% | — |
| 83 | INTECH INVESTMENT MANAGEMENT LLC | 28,10028,100 | $47,489 | 0.02% | TRIM -42% |
| 84 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 28,06628,066 | $47,432 | 0.02% | TRIM -18% |
| 85 | Mariner, LLC | 26,73926,739 | $45,115 | 0.02% | ADD 146% |
| 86 | China Universal Asset Management Co., Ltd. | 26,52526,525 | $44,827 | 0.02% | ADD 35% |
| 87 | BNP PARIBAS FINANCIAL MARKETS | 26,43426,434 | $44,673 | 0.02% | ADD 5% |
| 88 | Virtu Financial LLC | 25,83525,835 | $44,000 | 0.02% | NEW |
| 89 | NINE MASTS CAPITAL Ltd | 23,01823,018 | $38,900 | 0.02% | NEW |
| 90 | Engineers Gate Manager LP | 22,65822,658 | $38,292 | 0.02% | NEW |
| 91 | ProShare Advisors LLC | 21,70021,700 | $36,674 | 0.01% | TRIM -12% |
| 92 | NEW YORK STATE COMMON RETIREMENT FUND | 20,59320,593 | $34,802 | 0.01% | — |
| 93 | Bronte Capital Management Pty Ltd. | 19,28219,282 | $32,587 | 0.01% | — |
| 94 | Quadrature Capital Ltd | 17,77517,775 | $30,040 | 0.01% | NEW |
| 95 | CAPTRUST FINANCIAL ADVISORS | 16,99416,994 | $28,715 | 0.01% | ADD 30% |
| 96 | VOYA INVESTMENT MANAGEMENT LLC | 16,97116,971 | $28,681 | 0.01% | — |
| 97 | Stratos Wealth Partners, LTD. | 16,13116,131 | $27,261 | 0.01% | — |
| 98 | PRUDENTIAL FINANCIAL INC | 16,09516,095 | $27,201 | 0.01% | NEW |
| 99 | Tower Research Capital LLC (TRC) | 15,92315,923 | $26,910 | 0.01% | ADD 97% |
| 100 | Providence Wealth Advisors, LLC | 15,00015,000 | $25,875 | 0.01% | — |
† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.
Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.
| Holder | 2024-Q4 | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 | 2026-Q1 | Latest value |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 11.1M | 11.0M | 10.7M | 10.5M | 10.6M | 10.4M | $18M |
| VANGUARD CAPITAL MANAGEMENT LLC | — | — | — | — | — | 5.5M | $9M |
| SAMSARA BIOCAPITAL, LLC | — | — | — | — | — | 3.4M | $6M |
| GEODE CAPITAL MANAGEMENT, LLC | 2.6M | 2.7M | 2.7M | 2.7M | 2.7M | 3.1M | $5M |
| Kohlberg Kravis Roberts & Co. L.P. | 3.0M | 3.0M | 3.0M | 3.0M | 3.0M | 3.0M | $5M |
| STATE STREET CORP | 2.2M | 2.2M | 2.2M | 2.2M | 2.2M | 2.3M | $4M |
| TWO SIGMA INVESTMENTS, LP | 134K | — | — | 36K | 504K | 2.3M | $4M |
| Alyeska Investment Group, L.P. | — | — | — | — | — | 2.3M | $4M |
| CM Management, LLC | 2.0M | 2.1M | 2.3M | 2.1M | 2.1M | 2.1M | $4M |
| C WorldWide Group Holding A/S | 1.9M | 1.9M | 1.9M | 1.9M | 1.9M | 1.9M | $3M |
| TANG CAPITAL MANAGEMENT LLC | 3.6M | 5.1M | 5.1M | 5.1M | 2.7M | 1.9M | $3M |
| Hudson Bay Capital Management LP | 835K | 835K | 835K | 810K | 835K | 1.7M | $3M |
| PANAGORA ASSET MANAGEMENT INC | — | — | 794K | 1.4M | 1.6M | 1.5M | $2M |
| Propel Bio Management, LLC | — | — | — | — | — | 1.4M | $2M |
| AQR CAPITAL MANAGEMENT LLC | 1.2M | 668K | 769K | 903K | 886K | 1.2M | $2M |
Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.
Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding divides each quarter's as-filed 13F shares by the SEC cover-page share count dated to that same quarter (split-adjusted), not by today's count — so splits and buybacks don't move the line.
Short interest has its own tab now — open SI →
Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.
| Biggest buyers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC | +5,452,762 | $9M | OPEN |
| SAMSARA BIOCAPITAL, LLC | +3,428,571 | $6M | OPEN |
| Alyeska Investment Group, L.P. | +2,250,000 | $4M | OPEN |
| TWO SIGMA INVESTMENTS, LP | +1,798,126 | $3M | ADD |
| Propel Bio Management, LLC | +1,420,550 | $2M | OPEN |
| Biggest sellers | Δ shares | Δ value | |
|---|---|---|---|
| VANGUARD GROUP INC | −10,028,893 | $17M | CLOSE |
| TANG CAPITAL MANAGEMENT LLC | −837,761 | $1M | TRIM |
| JANE STREET GROUP, LLC | −563,016 | $951,497 | TRIM |
| MILLENNIUM MANAGEMENT LLC | −348,465 | $588,906 | TRIM |
| TWO SIGMA ADVISERS, LP | −307,600 | $519,844 | CLOSE |
The 2025-Q4 register is as-filed in ITS OWN share basis; every count below was rebased into the 2026-Q1 basis (no split in between, factor 1). Dollar figures value the SHARE delta at one price — the 2026-03-31 close — rather than differencing two filings' own reported values, which would mix the quarter's price move into the trade figure.
13Fs disclose LONG US-listed positions only — shorts, most derivatives, bonds and non-US listings are invisible here, and a filer's quarter-over-quarter change is not necessarily a trade (index rebalances, in-kind transfers and entity successions all read as flow).
| Quarter | Holders | Shares held | % shares out | Value held |
|---|---|---|---|---|
| 2026-Q1 | 156 | 59,140,522 | 39.5% | $100M |
| 2025-Q4 | 127 | 51,411,637 | 42.5% | $73M |
| 2025-Q3 | 114 | 51,723,744 | 44.5% | $85M |
| 2025-Q2 | 112 | 55,645,424 | 48.0% | $41M |
| 2025-Q1 | 117 | 62,006,325 | 53.5% | $50M |
| 2024-Q4 | 124 | 65,679,394 | 57.0% | $91M |
| 2024-Q3 | 128 | 77,377,393 | 67.2% | $126M |
| 2024-Q2 | 135 | 82,911,194 | 72.3% | $143M |
| 2024-Q1 | 137 | 88,390,353 | 78.4% | $212M |
| 2023-Q4 | 156 | 84,801,290 | 76.1% | $280M |
| 2023-Q3 | 169 | 94,070,307 | 99.6% | $349M |
| 2023-Q2 | 161 | 86,799,152 | 107.8% | $371M |
| 2023-Q1 | 163 | 78,731,713 | 98.9% | $538M |
| 2022-Q4 | 161 | 78,631,080 | 101.1% | $623M |
| 2022-Q3 | 174 | 77,391,215 | 99.6% | $744M |
| 2022-Q2 | 176 | 78,929,587 | 101.9% | $572M |
| 2022-Q1 | 184 | 76,034,526 | 98.4% | $981M |
| 2021-Q4 | 201 | 82,408,848 | 107.3% | $1.3B |
| 2021-Q3 | 188 | 76,119,278 | 99.5% | $1.2B |
| 2021-Q2 | 188 | 82,597,101 | 109.0% | $1.1B |
| 2021-Q1 | 205 | 80,337,418 | — | $1.2B |
| 2020-Q4 | 196 | 86,916,629 | — | $1.5B |
| 2020-Q3 | 201 | 85,939,273 | — | $1.6B |
| 2020-Q2 | 188 | 86,790,635 | — | $1.5B |
| 2020-Q1 | 186 | 74,680,336 | 105.7% | $1.2B |
| 2019-Q4 | 188 | 73,669,955 | 105.0% | $1.3B |
| 2019-Q3 | 167 | 69,362,167 | 99.4% | $1.4B |
| 2019-Q2 | 146 | 67,809,849 | 97.8% | $1.5B |
| 2019-Q1 | 117 | 68,766,923 | 99.3% | $938M |
| 2018-Q4 | 111 | 66,346,201 | 97.5% | $600M |
| 2018-Q3 | 109 | 67,614,492 | 99.7% | $1.1B |
| 2018-Q2 | 115 | 66,137,337 | 108.1% | $926M |
| 2018-Q1 | 103 | 55,290,128 | 91.9% | $611M |
| 2017-Q4 | 94 | 49,490,418 | 85.4% | $436M |
| 2017-Q3 | 93 | 46,998,936 | 91.5% | $628M |
| 2017-Q2 | 106 | 40,149,485 | 78.3% | $576M |
| 2017-Q1 | 109 | 37,551,375 | 73.4% | $794M |
| 2016-Q4 | 122 | 30,113,128 | 69.0% | $848M |
| 2016-Q3 | 117 | 28,142,865 | 64.9% | $754M |
| 2016-Q2 | 86 | 25,377,572 | 64.8% | $429M |
| 2016-Q1 | 75 | 18,234,723 | 46.6% | $387M |
| 2015-Q4 | 77 | 16,724,217 | 43.0% | $384M |
| 2015-Q3 | 78 | 16,151,049 | 42.2% | $334M |
| 2015-Q2 | 75 | 15,061,051 | 39.8% | $434M |
| 2015-Q1 | 51 | 7,268,457 | 21.8% | $222M |
| 2014-Q4 | 38 | 9,850,154 | 29.6% | $158M |
| QII |
| 2024-12-31 |
| SEC → |
Source: SEC Schedule 13D/13G structured XML. 13D = active intent; 13G filers report passively (Rule 13d-1(b) QII / 13d-1(c) Passive / 13d-1(d) Exempt) and are not activists. Percent and delta are the group aggregate the filing reports. Structured 13D/G coverage begins December 2024 (SEC XML mandate).
