CDXS US Equity

CODEXIS, INC.

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Materials · Industrial Organic Chemicals · CIK 1200375 · FYE 1231

$1.50

-0.05 (-3.23%)

USD · as of 2026-07-28 · marketstack

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Institutional ownership· 13F filers holding CDXS · 2026-Q1 methodology → sources →

133 holders

% of shares outstanding held

72.0%

Shares held (13F)

65,478,809

Reporting holders

133

Top holders

largest 100 of 133 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Aberdeen Group plc	8,680,3688.7M	$14M	9.55%	ADD 9%
2	BlackRock, Inc.	7,028,7737.0M	$11M	7.73%	TRIM -5%
3	Opaleye Management Inc.	6,785,0006.8M	$11M	7.46%	—
4	Nantahala Capital Management, LLC	4,123,6134.1M	$7M	4.54%	ADD 3%
5	MILLENNIUM MANAGEMENT LLC	3,998,1304.0M	$7M	4.40%	ADD 28%
6	Telemark Asset Management, LLC	3,846,4113.8M	$6M	4.23%	—
7	VANGUARD CAPITAL MANAGEMENT LLC	3,668,5073.7M	$6M	4.04%	NEW†
8	AMERIPRISE FINANCIAL INC	3,400,4963.4M	$6M	3.74%	TRIM -10%
9	UBS Group AG	2,183,7752.2M	$4M	2.40%	ADD 170%
10	GEODE CAPITAL MANAGEMENT, LLC	1,885,3531.9M	$3M	2.07%	TRIM -7%
11	STATE STREET CORP	1,666,9541.7M	$3M	1.83%	ADD 4%
12	JACOBS LEVY EQUITY MANAGEMENT, INC	1,088,0271.1M	$2M	1.20%	TRIM -4%
13	D. E. Shaw & Co., Inc.	979,847979,847	$2M	1.08%	ADD 56%
14	JANE STREET GROUP, LLC	919,964919,964	$1M	1.01%	ADD 207%
15	VANGUARD PORTFOLIO MANAGEMENT LLC	879,339879,339	$1M	0.97%	NEW
16	Private Advisor Group, LLC	847,001847,001	$1M	0.93%	ADD 29%
17	GOLDMAN SACHS GROUP INC	824,870824,870	$1M	0.91%	ADD 15%
18	Assenagon Asset Management S.A.	751,170751,170	$1M	0.83%	ADD 33%
19	FRANKLIN RESOURCES INC	688,210688,210	$1M	0.76%	TRIM -7%
20	NORTHERN TRUST CORP	657,139657,139	$1M	0.72%	—
21	AQR CAPITAL MANAGEMENT LLC	608,601608,601	$992,021	0.67%	ADD 841%
22	Post Resch Tallon Group Inc.	571,478571,478	$974,941	0.63%	ADD 12%
23	VANGUARD FIDUCIARY TRUST CO	551,008551,008	$898,143	0.61%	NEW
24	TUDOR INVESTMENT CORP ET AL	537,833537,833	$876,668	0.59%	—
25	PERKINS CAPITAL MANAGEMENT INC	527,500527,500	$859,825	0.58%	—
26	MORGAN STANLEY	472,841472,841	$770,731	0.52%	ADD 10%
27	Stonepine Capital Management, LLC	417,994417,994	$681,330	0.46%	ADD 63%
28	FMR LLC	412,597412,597	$672,533	0.45%	TRIM -36%
29	Nuveen, LLC	367,443367,443	$598,932	0.40%	ADD 22%
30	Diametric Capital, LP	359,268359,268	$585,606	0.40%	ADD 220%
31	CITADEL ADVISORS LLC	287,595287,595	$468,780	0.32%	TRIM -42%
32	DIMENSIONAL FUND ADVISORS LP	284,636284,636	$463,390	0.31%	TRIM -30%
33	LAZARD ASSET MANAGEMENT LLC	282,380282,380	$460,279	0.31%	TRIM -34%
34	Potomac Capital Management, Inc.	274,200274,200	$446,946	0.30%	TRIM -9%
35	PLATINUM INVESTMENT MANAGEMENT LTD	264,464264,464	$431,076	0.29%	—
36	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	242,211242,211	$394,804	0.27%	TRIM -12%
37	TWO SIGMA INVESTMENTS, LP	241,955241,955	$394,387	0.27%	ADD 508%
38	ROYAL BANK OF CANADA	215,365215,365	$351,000	0.24%	ADD 85%
39	Bank of New York Mellon Corp	209,645209,645	$341,720	0.23%	ADD 2%
40	RENAISSANCE TECHNOLOGIES LLC	198,733198,733	$323,935	0.22%	TRIM -73%
41	ALGERT GLOBAL LLC	197,447197,447	$322,000	0.22%	NEW
42	Invesco Ltd.	180,925180,925	$294,907	0.20%	ADD 4%
43	BANK OF AMERICA CORP /DE/	173,955173,955	$283,547	0.19%	ADD 149%
44	XTX Topco Ltd	167,542167,542	$273,093	0.18%	ADD 125%
45	BARCLAYS PLC	155,093155,093	$252,802	0.17%	TRIM -37%
46	LOS ANGELES CAPITAL MANAGEMENT LLC	133,665133,665	$217,874	0.15%	NEW
47	BRIDGEWAY CAPITAL MANAGEMENT, LLC	125,908125,908	$205,230	0.14%	TRIM -17%
48	ACADIAN ASSET MANAGEMENT LLC	123,749123,749	$200,000	0.14%	ADD 40%
49	ALLIANCEBERNSTEIN L.P.	118,130118,130	$192,552	0.13%	—
50	GSA CAPITAL PARTNERS LLP	116,923116,923	$191,000	0.13%	NEW
51	RHUMBLINE ADVISERS	99,31499,314	$161,871	0.11%	TRIM -9%
52	STRS OHIO	99,10099,100	$161,533	0.11%	—
53	DEUTSCHE BANK AG\	93,08293,082	$151,724	0.10%	ADD 81%
54	LPL Financial LLC	75,06075,060	$122,348	0.08%	TRIM -5%
55	Quadrature Capital Ltd	64,19964,199	$104,644	0.07%	ADD 18%
56	PRICE T ROWE ASSOCIATES INC /MD/	63,59363,593	$104,000	0.07%	ADD 44%
57	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	63,75363,753	$103,917	0.07%	ADD 60%
58	Russell Investments Group, Ltd.	58,47958,479	$95,320	0.06%	—
59	WELLS FARGO & COMPANY/MN	56,63156,631	$92,309	0.06%	TRIM -54%
60	Krilogy Financial LLC	36,25736,257	$92,093	0.04%	ADD 20%
61	PRELUDE CAPITAL MANAGEMENT, LLC	54,68054,680	$89,128	0.06%	ADD 57%
62	SUSQUEHANNA INTERNATIONAL GROUP, LLP	53,24153,241	$86,783	0.06%	TRIM -82%
63	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	42,41842,418	$69,141	0.05%	ADD 2%
64	CWM, LLC	39,07739,077	$63,696	0.04%	ADD 2078%
65	JPMORGAN CHASE & CO	41,40741,407	$62,939	0.05%	—
66	OSAIC HOLDINGS, INC.	36,56536,565	$59,600	0.04%	—
67	ENVESTNET ASSET MANAGEMENT INC	36,41436,414	$59,355	0.04%	ADD 113%
68	Frec Markets, Inc.	36,25336,253	$59,092	0.04%	NEW
69	BANK OF MONTREAL /CAN/	34,99834,998	$57,047	0.04%	NEW
70	Cerity Partners LLC	32,89232,892	$53,614	0.04%	NEW
71	Vanguard Global Advisers, LLC	32,60232,602	$53,141	0.04%	NEW
72	COMMONWEALTH EQUITY SERVICES, LLC	31,50031,500	$51,340	0.03%	TRIM -16%
73	BLAIR WILLIAM & CO/IL	30,01830,018	$48,929	0.03%	—
74	EVERGREEN CAPITAL MANAGEMENT LLC	29,00029,000	$47,270	0.03%	—
75	Capital Advisors, Ltd. LLC	28,89028,890	$47,000	0.03%	NEW
76	MANUFACTURERS LIFE INSURANCE COMPANY, THE	27,43927,439	$44,726	0.03%	TRIM -16%
77	GUGGENHEIM CAPITAL LLC	26,95026,950	$43,929	0.03%	—
78	INTECH INVESTMENT MANAGEMENT LLC	24,24724,247	$39,523	0.03%	TRIM -32%
79	Mariner, LLC	23,52923,529	$38,325	0.03%	NEW
80	Elmwood Wealth Management, Inc.	21,69521,695	$35,363	0.02%	—
81	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	18,85918,859	$34,323	0.02%	NEW
82	BNP PARIBAS FINANCIAL MARKETS	20,69120,691	$33,726	0.02%	—
83	FNY Investment Advisers, LLC	20,00020,000	$32,000	0.02%	NEW
84	Police & Firemen's Retirement System of New Jersey	19,44119,441	$31,689	0.02%	—
85	Vanguard Personalized Indexing Management, LLC	18,18318,183	$29,638	0.02%	NEW
86	MERCER GLOBAL ADVISORS INC /ADV	17,67917,679	$28,817	0.02%	NEW
87	ProShare Advisors LLC	16,97616,976	$27,671	0.02%	TRIM -16%
88	NEW YORK STATE COMMON RETIREMENT FUND	16,88816,888	$27,527	0.02%	—
89	China Universal Asset Management Co., Ltd.	16,02916,029	$26,127	0.02%	ADD 9%
90	Navalign, LLC	15,34015,340	$25,004	0.02%	—
91	VOYA INVESTMENT MANAGEMENT LLC	14,81614,816	$24,150	0.02%	—
92	StoneX Group Inc.	14,09614,096	$22,976	0.02%	NEW
93	Fiduciary Trust Co	13,62013,620	$22,201	0.01%	—
94	PRUDENTIAL FINANCIAL INC	13,58013,580	$22,135	0.01%	NEW
95	Tower Research Capital LLC (TRC)	13,57213,572	$22,122	0.01%	TRIM -50%
96	Simplicity Wealth,LLC	13,30813,308	$21,692	0.01%	NEW
97	CITIGROUP INC	11,90911,909	$19,411	0.01%	ADD 120%
98	Pallas Capital Advisors LLC	10,32510,325	$16,830	0.01%	NEW
99	VICTORY CAPITAL MANAGEMENT INC	10,08110,081	$16,432	0.01%	—
100	GAMCO INVESTORS, INC. ET AL	10,00010,000	$16,300	0.01%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Aberdeen Group plc

509K

606K

4.2M

4.1M

8.0M

8.7M

$14M

BlackRock, Inc.

7.6M

7.1M

7.4M

7.0M

$11M

Opaleye Management Inc.

8.8M

9.5M

12.6M

12.8M

6.8M

$11M

Nantahala Capital Management, LLC

2.8M

4.0M

4.1M

$7M

MILLENNIUM MANAGEMENT LLC

36K

—

117K

4.1M

3.1M

4.0M

$7M

Telemark Asset Management, LLC

3.0M

4.0M

3.8M

$6M

VANGUARD CAPITAL MANAGEMENT LLC

—

3.7M

$6M

AMERIPRISE FINANCIAL INC

2.4M

2.5M

2.6M

2.8M

3.8M

3.4M

$6M

UBS Group AG

53K

292K

174K

522K

810K

2.2M

$4M

GEODE CAPITAL MANAGEMENT, LLC

1.9M

2.0M

1.9M

$3M

STATE STREET CORP

1.6M

1.5M

1.6M

1.7M

$3M

JACOBS LEVY EQUITY MANAGEMENT, INC

861K

1.1M

1.2M

1.1M

$2M

D. E. Shaw & Co., Inc.

—

174K

628K

980K

$2M

JANE STREET GROUP, LLC

—

50K

300K

920K

$1M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

879K

$1M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	133	65,478,809	72.0%	$107M
2025-Q4

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · CDXS

Large holders — 13G, passive (top 5 of 9 by % of class)

Holder

% of class

Type

As of

Opaleye Management Inc.

7.47%

Passive

2026-03-31

SEC →

Aberdeen Group plc

7.45%

QII

2026-06-30

SEC →

BlackRock, Inc.

7.2%

QII

2025-03-31

SEC →

INTEGRATED CORE STRATEGIES (US) LLC

5.2%

Passive

2026-04-09

SEC →

LYTTON LAURENCE W

Passive

Institutional ownership· 13F filers holding CDXS · 2026-Q1 methodology → sources →

133 holders

% of shares outstanding held

72.0%

Shares held (13F)

65,478,809

Reporting holders

133

Top holders

largest 100 of 133 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	Aberdeen Group plc	8,680,3688.7M	$14M	9.55%	ADD 9%
2	BlackRock, Inc.	7,028,7737.0M	$11M	7.73%	TRIM -5%
3	Opaleye Management Inc.	6,785,0006.8M	$11M	7.46%	—
4	Nantahala Capital Management, LLC	4,123,6134.1M	$7M	4.54%	ADD 3%
5	MILLENNIUM MANAGEMENT LLC	3,998,1304.0M	$7M	4.40%	ADD 28%
6	Telemark Asset Management, LLC	3,846,4113.8M	$6M	4.23%	—
7	VANGUARD CAPITAL MANAGEMENT LLC	3,668,5073.7M	$6M	4.04%	NEW†
8	AMERIPRISE FINANCIAL INC	3,400,4963.4M	$6M	3.74%	TRIM -10%
9	UBS Group AG	2,183,7752.2M	$4M	2.40%	ADD 170%
10	GEODE CAPITAL MANAGEMENT, LLC	1,885,3531.9M	$3M	2.07%	TRIM -7%
11	STATE STREET CORP	1,666,9541.7M	$3M	1.83%	ADD 4%
12	JACOBS LEVY EQUITY MANAGEMENT, INC	1,088,0271.1M	$2M	1.20%	TRIM -4%
13	D. E. Shaw & Co., Inc.	979,847979,847	$2M	1.08%	ADD 56%
14	JANE STREET GROUP, LLC	919,964919,964	$1M	1.01%	ADD 207%
15	VANGUARD PORTFOLIO MANAGEMENT LLC	879,339879,339	$1M	0.97%	NEW
16	Private Advisor Group, LLC	847,001847,001	$1M	0.93%	ADD 29%
17	GOLDMAN SACHS GROUP INC	824,870824,870	$1M	0.91%	ADD 15%
18	Assenagon Asset Management S.A.	751,170751,170	$1M	0.83%	ADD 33%
19	FRANKLIN RESOURCES INC	688,210688,210	$1M	0.76%	TRIM -7%
20	NORTHERN TRUST CORP	657,139657,139	$1M	0.72%	—
21	AQR CAPITAL MANAGEMENT LLC	608,601608,601	$992,021	0.67%	ADD 841%
22	Post Resch Tallon Group Inc.	571,478571,478	$974,941	0.63%	ADD 12%
23	VANGUARD FIDUCIARY TRUST CO	551,008551,008	$898,143	0.61%	NEW
24	TUDOR INVESTMENT CORP ET AL	537,833537,833	$876,668	0.59%	—
25	PERKINS CAPITAL MANAGEMENT INC	527,500527,500	$859,825	0.58%	—
26	MORGAN STANLEY	472,841472,841	$770,731	0.52%	ADD 10%
27	Stonepine Capital Management, LLC	417,994417,994	$681,330	0.46%	ADD 63%
28	FMR LLC	412,597412,597	$672,533	0.45%	TRIM -36%
29	Nuveen, LLC	367,443367,443	$598,932	0.40%	ADD 22%
30	Diametric Capital, LP	359,268359,268	$585,606	0.40%	ADD 220%
31	CITADEL ADVISORS LLC	287,595287,595	$468,780	0.32%	TRIM -42%
32	DIMENSIONAL FUND ADVISORS LP	284,636284,636	$463,390	0.31%	TRIM -30%
33	LAZARD ASSET MANAGEMENT LLC	282,380282,380	$460,279	0.31%	TRIM -34%
34	Potomac Capital Management, Inc.	274,200274,200	$446,946	0.30%	TRIM -9%
35	PLATINUM INVESTMENT MANAGEMENT LTD	264,464264,464	$431,076	0.29%	—
36	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	242,211242,211	$394,804	0.27%	TRIM -12%
37	TWO SIGMA INVESTMENTS, LP	241,955241,955	$394,387	0.27%	ADD 508%
38	ROYAL BANK OF CANADA	215,365215,365	$351,000	0.24%	ADD 85%
39	Bank of New York Mellon Corp	209,645209,645	$341,720	0.23%	ADD 2%
40	RENAISSANCE TECHNOLOGIES LLC	198,733198,733	$323,935	0.22%	TRIM -73%
41	ALGERT GLOBAL LLC	197,447197,447	$322,000	0.22%	NEW
42	Invesco Ltd.	180,925180,925	$294,907	0.20%	ADD 4%
43	BANK OF AMERICA CORP /DE/	173,955173,955	$283,547	0.19%	ADD 149%
44	XTX Topco Ltd	167,542167,542	$273,093	0.18%	ADD 125%
45	BARCLAYS PLC	155,093155,093	$252,802	0.17%	TRIM -37%
46	LOS ANGELES CAPITAL MANAGEMENT LLC	133,665133,665	$217,874	0.15%	NEW
47	BRIDGEWAY CAPITAL MANAGEMENT, LLC	125,908125,908	$205,230	0.14%	TRIM -17%
48	ACADIAN ASSET MANAGEMENT LLC	123,749123,749	$200,000	0.14%	ADD 40%
49	ALLIANCEBERNSTEIN L.P.	118,130118,130	$192,552	0.13%	—
50	GSA CAPITAL PARTNERS LLP	116,923116,923	$191,000	0.13%	NEW
51	RHUMBLINE ADVISERS	99,31499,314	$161,871	0.11%	TRIM -9%
52	STRS OHIO	99,10099,100	$161,533	0.11%	—
53	DEUTSCHE BANK AG\	93,08293,082	$151,724	0.10%	ADD 81%
54	LPL Financial LLC	75,06075,060	$122,348	0.08%	TRIM -5%
55	Quadrature Capital Ltd	64,19964,199	$104,644	0.07%	ADD 18%
56	PRICE T ROWE ASSOCIATES INC /MD/	63,59363,593	$104,000	0.07%	ADD 44%
57	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	63,75363,753	$103,917	0.07%	ADD 60%
58	Russell Investments Group, Ltd.	58,47958,479	$95,320	0.06%	—
59	WELLS FARGO & COMPANY/MN	56,63156,631	$92,309	0.06%	TRIM -54%
60	Krilogy Financial LLC	36,25736,257	$92,093	0.04%	ADD 20%
61	PRELUDE CAPITAL MANAGEMENT, LLC	54,68054,680	$89,128	0.06%	ADD 57%
62	SUSQUEHANNA INTERNATIONAL GROUP, LLP	53,24153,241	$86,783	0.06%	TRIM -82%
63	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	42,41842,418	$69,141	0.05%	ADD 2%
64	CWM, LLC	39,07739,077	$63,696	0.04%	ADD 2078%
65	JPMORGAN CHASE & CO	41,40741,407	$62,939	0.05%	—
66	OSAIC HOLDINGS, INC.	36,56536,565	$59,600	0.04%	—
67	ENVESTNET ASSET MANAGEMENT INC	36,41436,414	$59,355	0.04%	ADD 113%
68	Frec Markets, Inc.	36,25336,253	$59,092	0.04%	NEW
69	BANK OF MONTREAL /CAN/	34,99834,998	$57,047	0.04%	NEW
70	Cerity Partners LLC	32,89232,892	$53,614	0.04%	NEW
71	Vanguard Global Advisers, LLC	32,60232,602	$53,141	0.04%	NEW
72	COMMONWEALTH EQUITY SERVICES, LLC	31,50031,500	$51,340	0.03%	TRIM -16%
73	BLAIR WILLIAM & CO/IL	30,01830,018	$48,929	0.03%	—
74	EVERGREEN CAPITAL MANAGEMENT LLC	29,00029,000	$47,270	0.03%	—
75	Capital Advisors, Ltd. LLC	28,89028,890	$47,000	0.03%	NEW
76	MANUFACTURERS LIFE INSURANCE COMPANY, THE	27,43927,439	$44,726	0.03%	TRIM -16%
77	GUGGENHEIM CAPITAL LLC	26,95026,950	$43,929	0.03%	—
78	INTECH INVESTMENT MANAGEMENT LLC	24,24724,247	$39,523	0.03%	TRIM -32%
79	Mariner, LLC	23,52923,529	$38,325	0.03%	NEW
80	Elmwood Wealth Management, Inc.	21,69521,695	$35,363	0.02%	—
81	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	18,85918,859	$34,323	0.02%	NEW
82	BNP PARIBAS FINANCIAL MARKETS	20,69120,691	$33,726	0.02%	—
83	FNY Investment Advisers, LLC	20,00020,000	$32,000	0.02%	NEW
84	Police & Firemen's Retirement System of New Jersey	19,44119,441	$31,689	0.02%	—
85	Vanguard Personalized Indexing Management, LLC	18,18318,183	$29,638	0.02%	NEW
86	MERCER GLOBAL ADVISORS INC /ADV	17,67917,679	$28,817	0.02%	NEW
87	ProShare Advisors LLC	16,97616,976	$27,671	0.02%	TRIM -16%
88	NEW YORK STATE COMMON RETIREMENT FUND	16,88816,888	$27,527	0.02%	—
89	China Universal Asset Management Co., Ltd.	16,02916,029	$26,127	0.02%	ADD 9%
90	Navalign, LLC	15,34015,340	$25,004	0.02%	—
91	VOYA INVESTMENT MANAGEMENT LLC	14,81614,816	$24,150	0.02%	—
92	StoneX Group Inc.	14,09614,096	$22,976	0.02%	NEW
93	Fiduciary Trust Co	13,62013,620	$22,201	0.01%	—
94	PRUDENTIAL FINANCIAL INC	13,58013,580	$22,135	0.01%	NEW
95	Tower Research Capital LLC (TRC)	13,57213,572	$22,122	0.01%	TRIM -50%
96	Simplicity Wealth,LLC	13,30813,308	$21,692	0.01%	NEW
97	CITIGROUP INC	11,90911,909	$19,411	0.01%	ADD 120%
98	Pallas Capital Advisors LLC	10,32510,325	$16,830	0.01%	NEW
99	VICTORY CAPITAL MANAGEMENT INC	10,08110,081	$16,432	0.01%	—
100	GAMCO INVESTORS, INC. ET AL	10,00010,000	$16,300	0.01%	—

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

Aberdeen Group plc

509K

606K

4.2M

4.1M

8.0M

8.7M

$14M

BlackRock, Inc.

7.6M

7.1M

7.4M

7.0M

$11M

Opaleye Management Inc.

8.8M

9.5M

12.6M

12.8M

6.8M

$11M

Nantahala Capital Management, LLC

2.8M

4.0M

4.1M

$7M

MILLENNIUM MANAGEMENT LLC

36K

—

117K

4.1M

3.1M

4.0M

$7M

Telemark Asset Management, LLC

3.0M

4.0M

3.8M

$6M

VANGUARD CAPITAL MANAGEMENT LLC

—

3.7M

$6M

AMERIPRISE FINANCIAL INC

2.4M

2.5M

2.6M

2.8M

3.8M

3.4M

$6M

UBS Group AG

53K

292K

174K

522K

810K

2.2M

$4M

GEODE CAPITAL MANAGEMENT, LLC

1.9M

2.0M

1.9M

$3M

STATE STREET CORP

1.6M

1.5M

1.6M

1.7M

$3M

JACOBS LEVY EQUITY MANAGEMENT, INC

861K

1.1M

1.2M

1.1M

$2M

D. E. Shaw & Co., Inc.

—

174K

628K

980K

$2M

JANE STREET GROUP, LLC

—

50K

300K

920K

$1M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

879K

$1M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	133	65,478,809	72.0%	$107M
2025-Q4

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · CDXS

Large holders — 13G, passive (top 5 of 9 by % of class)

Holder

% of class

Type

As of

Opaleye Management Inc.

7.47%

Passive

2026-03-31

SEC →

Aberdeen Group plc

7.45%

QII

2026-06-30

SEC →

BlackRock, Inc.

7.2%

QII

2025-03-31

SEC →

INTEGRATED CORE STRATEGIES (US) LLC

5.2%

Passive

2026-04-09

SEC →

LYTTON LAURENCE W

Passive

CDXS US Equity☆

Institutional ownership· 13F filers holding CDXS · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CDXS

Institutional ownership· 13F filers holding CDXS · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · CDXS

CDXS US Equity