BBIO US Equity

BridgeBio Pharma, Inc.

Nasdaq+ Compare Tear sheet →

Health Care · Pharmaceutical Preparations · CIK 1743881 · FYE 1231

$83.54

-2.01 (-2.35%)

USD · as of 2026-07-29 · marketstack

Switch Ticker

Institutional ownership· 13F filers holding BBIO · 2026-Q1 methodology → sources →

457 holders

% of shares outstanding held

99.4%

Shares held (13F)

194,641,640

Reporting holders

457

Top holders

largest 100 of 457 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	14,207,75714.2M	$1.1B	7.25%	TRIM -2%
2	Kohlberg Kravis Roberts & Co. L.P.	13,260,97113.3M	$985M	6.77%	—
3	JANUS HENDERSON GROUP PLC	13,179,01313.2M	$979M	6.73%	ADD 20%
4	VIKING GLOBAL INVESTORS LPtracked	11,842,43411.8M	$879M	6.05%	TRIM -18%
5	FARALLON CAPITAL MANAGEMENT LLC	9,365,4639.4M	$695M	4.78%	ADD 4%
6	VANGUARD PORTFOLIO MANAGEMENT LLC	8,080,5738.1M	$600M	4.13%	NEW†
7	VANGUARD CAPITAL MANAGEMENT LLC	7,759,4957.8M	$576M	3.96%	NEW†
8	DIAMANT ASSET MANAGEMENT, INC.	527,246527,246	$527M	0.27%	NEW
9	Aisling Capital Management LP	5,089,6115.1M	$378M	2.60%	—
10	GEODE CAPITAL MANAGEMENT, LLC	4,918,0304.9M	$372M	2.51%	ADD 11%
11	STATE STREET CORP	4,934,3204.9M	$366M	2.52%	—
12	Invesco Ltd.	4,592,8144.6M	$341M	2.34%	TRIM -5%
13	PRICE T ROWE ASSOCIATES INC /MD/	3,801,6553.8M	$282M	1.94%	—
14	Frazier Life Sciences Management, L.P.	3,448,1393.4M	$256M	1.76%	TRIM -3%
15	CITADEL ADVISORS LLC	3,173,9403.2M	$236M	1.62%	ADD 355%
16	TWO SIGMA INVESTMENTS, LP	3,120,6313.1M	$232M	1.59%	ADD 60%
17	D. E. Shaw & Co., Inc.	2,545,4862.5M	$189M	1.30%	ADD 15%
18	Polar Capital Holdings Plc	2,519,3062.5M	$187M	1.29%	ADD 94%
19	WELLINGTON MANAGEMENT GROUP LLP	2,483,9532.5M	$184M	1.27%	ADD 6%
20	FRANKLIN RESOURCES INC	2,438,9252.4M	$181M	1.25%	ADD 13%
21	FMR LLC	2,343,7542.3M	$174M	1.20%	—
22	UBS Group AG	2,026,8212.0M	$151M	1.03%	ADD 8%
23	MANUFACTURERS LIFE INSURANCE COMPANY, THE	1,977,0802.0M	$147M	1.01%	—
24	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,976,0942.0M	$147M	1.01%	—
25	ALLIANCEBERNSTEIN L.P.	1,908,9071.9M	$146M	0.97%	TRIM -7%
26	GOLDMAN SACHS GROUP INC	1,897,7161.9M	$141M	0.97%	ADD 6%
27	MORGAN STANLEY	1,877,3591.9M	$139M	0.96%	ADD 34%
28	SC US (TTGP), LTD.	1,860,3641.9M	$138M	0.95%	—
29	JANE STREET GROUP, LLC	1,757,6721.8M	$131M	0.90%	ADD 414%
30	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	1,534,7361.5M	$114M	0.78%	TRIM -11%
31	NORTHERN TRUST CORP	1,403,6421.4M	$104M	0.72%	ADD 4%
32	Pictet Asset Management Holding SA	1,381,1841.4M	$101M	0.71%	ADD 9%
33	PRINCIPAL FINANCIAL GROUP INC	1,330,4151.3M	$99M	0.68%	—
34	BNP PARIBAS FINANCIAL MARKETS	1,307,1761.3M	$97M	0.67%	TRIM -18%
35	BANK OF AMERICA CORP /DE/	1,285,7481.3M	$95M	0.66%	ADD 19%
36	Hood River Capital Management LLC	1,265,0801.3M	$94M	0.65%	—
37	Laurion Capital Management LP	1,262,6511.3M	$94M	0.64%	TRIM -10%
38	AMERIPRISE FINANCIAL INC	1,248,5211.2M	$93M	0.64%	ADD 48%
39	JPMORGAN CHASE & CO	1,312,2591.3M	$91M	0.67%	ADD 53%
40	VANGUARD FIDUCIARY TRUST CO	1,175,1351.2M	$87M	0.60%	NEW
41	Driehaus Capital Management LLC	1,146,6711.1M	$85M	0.59%	TRIM -32%
42	AMERICAN CENTURY COMPANIES INC	1,090,3261.1M	$81M	0.56%	—
43	LORD, ABBETT & CO. LLC	1,023,3411.0M	$76M	0.52%	ADD 31%
44	GW&K Investment Management, LLC	962,643962,643	$71M	0.49%	ADD 54%
45	FRONTIER CAPITAL MANAGEMENT CO LLC	957,989957,989	$71M	0.49%	ADD 16%
46	Clearbridge Investments, LLC	951,200951,200	$71M	0.49%	ADD 91%
47	Allspring Global Investments Holdings, LLC	889,356889,356	$66M	0.45%	TRIM -11%
48	Cormorant Asset Management, LP	850,000850,000	$63M	0.43%	TRIM -29%
49	Deep Track Capital, LP	841,445841,445	$62M	0.43%	ADD 4%
50	Ensign Peak Advisors, Inc	836,552836,552	$62M	0.43%	TRIM -34%
51	Capital Research Global Investors	763,702763,702	$57M	0.39%	TRIM -61%
52	CITIGROUP INC	746,483746,483	$55M	0.38%	ADD 7%
53	PANAGORA ASSET MANAGEMENT INC	742,117742,117	$55M	0.38%	—
54	First Turn Management, LLC	695,718695,718	$52M	0.36%	ADD 17%
55	MILLENNIUM MANAGEMENT LLC	633,283633,283	$47M	0.32%	ADD 1631%
56	ADAGE CAPITAL PARTNERS GP, L.L.C.	599,000599,000	$44M	0.31%	ADD 18%
57	FEDERATED HERMES, INC.	588,434588,434	$44M	0.30%	—
58	Bank of New York Mellon Corp	577,283577,283	$43M	0.29%	TRIM -3%
59	PRIMECAP MANAGEMENT CO/CA/	569,180569,180	$42M	0.29%	—
60	Nuveen, LLC	562,696562,696	$42M	0.29%	ADD 14%
61	DIMENSIONAL FUND ADVISORS LP	561,945561,945	$42M	0.29%	ADD 47%
62	Squarepoint Ops LLC	556,324556,324	$41M	0.28%	ADD 107%
63	VOYA INVESTMENT MANAGEMENT LLC	538,980538,980	$40M	0.28%	TRIM -8%
64	EMERALD ADVISERS, LLC	515,361515,361	$38M	0.26%	TRIM -4%
65	EVENTIDE ASSET MANAGEMENT, LLC	437,130437,130	$32M	0.22%	ADD 21%
66	Catalio Capital Management, LP	432,014432,014	$32M	0.22%	NEW
67	VOLORIDGE INVESTMENT MANAGEMENT, LLC	426,583426,583	$32M	0.22%	TRIM -33%
68	BARCLAYS PLC	423,888423,888	$31M	0.22%	TRIM -32%
69	GILDER GAGNON HOWE & CO LLC	420,325420,325	$31M	0.21%	TRIM -8%
70	Sofinnova Investments, Inc.	409,183409,183	$30M	0.21%	TRIM -43%
71	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	402,948402,948	$30M	0.21%	TRIM -11%
72	SUSQUEHANNA INTERNATIONAL GROUP, LLP	398,943398,943	$30M	0.20%	TRIM -18%
73	RENAISSANCE TECHNOLOGIES LLC	365,772365,772	$27M	0.19%	NEW
74	1832 Asset Management L.P.	356,400356,400	$26M	0.18%	ADD 682%
75	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	352,831352,831	$26M	0.18%	TRIM -57%
76	Russell Investments Group, Ltd.	351,719351,719	$26M	0.18%	TRIM -15%
77	Fisher Asset Management, LLC	351,628351,628	$26M	0.18%	ADD 51%
78	Balyasny Asset Management L.P.	350,096350,096	$26M	0.18%	ADD 49%
79	FIRST TRUST ADVISORS LP	339,907339,907	$25M	0.17%	ADD 21%
80	MARSHALL WACE, LLP	334,382334,382	$25M	0.17%	ADD 348%
81	Fiera Capital Corp	322,690322,690	$24M	0.16%	NEW
82	EMERALD MUTUAL FUND ADVISERS TRUST	320,211320,211	$24M	0.16%	—
83	NOMURA HOLDINGS INC	318,563318,563	$24M	0.16%	ADD 3%
84	Woodline Partners LP	301,012301,012	$22M	0.15%	—
85	RAYMOND JAMES FINANCIAL INC	311,959311,959	$22M	0.16%	ADD 165%
86	Nicholas Investment Partners, LP	298,909298,909	$22M	0.15%	ADD 5%
87	DEUTSCHE BANK AG\	296,683296,683	$22M	0.15%	TRIM -22%
88	SEI INVESTMENTS CO	288,075288,075	$21M	0.15%	ADD 28%
89	Swiss National Bank	286,000286,000	$21M	0.15%	—
90	Legal & General Group Plc	284,917284,917	$21M	0.15%	TRIM -15%
91	ALGERT GLOBAL LLC	283,921283,921	$21M	0.14%	TRIM -17%
92	Candriam S.C.A.	278,888278,888	$21M	0.14%	—
93	Integral Health Asset Management, LLC	275,000275,000	$20M	0.14%	NEW
94	Eagle Health Investments LP	267,031267,031	$20M	0.14%	ADD 3%
95	Bridgewater Associates, LP	259,459259,459	$19M	0.13%	ADD 501%
96	PFM Health Sciences, LP	257,747257,747	$19M	0.13%	TRIM -16%
97	Artisan Partners Limited Partnership	254,392254,392	$19M	0.13%	TRIM -9%
98	VICTORY CAPITAL MANAGEMENT INC	254,007254,007	$19M	0.13%	TRIM -8%
99	California Public Employees Retirement System	253,479253,479	$19M	0.13%	ADD 22%
100	SPHERA FUNDS MANAGEMENT LTD.	245,246245,246	$18M	0.13%	ADD 128%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

13.7M

13.4M

14.3M

14.4M

14.5M

14.2M

$1.1B

Kohlberg Kravis Roberts & Co. L.P.

25.3M

19.3M

13.3M

$985M

JANUS HENDERSON GROUP PLC

4.9M

7.2M

9.3M

8.7M

11.0M

13.2M

$979M

VIKING GLOBAL INVESTORS LPtracked

25.1M

22.1M

18.6M

16.0M

14.4M

11.8M

$879M

FARALLON CAPITAL MANAGEMENT LLC

4.2M

5.7M

7.9M

8.2M

9.0M

9.4M

$695M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

8.1M

$600M

VANGUARD CAPITAL MANAGEMENT LLC

—

7.8M

$576M

DIAMANT ASSET MANAGEMENT, INC.

—

527K

$527M

Aisling Capital Management LP

6.1M

5.1M

$378M

GEODE CAPITAL MANAGEMENT, LLC

3.4M

3.5M

3.7M

3.9M

4.4M

4.9M

$372M

STATE STREET CORP

6.2M

5.7M

5.9M

5.6M

5.0M

4.9M

$366M

Invesco Ltd.

893K

2.2M

2.8M

3.9M

4.8M

4.6M

$341M

PRICE T ROWE ASSOCIATES INC /MD/

991K

1.2M

961K

1.6M

3.8M

$282M

Frazier Life Sciences Management, L.P.

3.8M

3.5M

3.4M

$256M

CITADEL ADVISORS LLC

1.3M

2.9M

332K

—

698K

3.2M

$236M

Shares reported each quarter by the largest current holders. Green = added vs the prior filing, red = trimmed, grey = roughly held; a dash is a quarter with no 13F on file (a gap is skipped, not read as an exit). 13F is filed up to 45 days after quarter-end. Up to 40 quarters (10 years) available — use the selector above.

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	457	194,641,640	99.4%	$14.9B
2025-Q4	432	191,094,399	97.6%	$14.4B
2025-Q3	393	185,445,803	94.7%	$9.6B
2025-Q2	360	189,033,467	96.5%	$8.2B
2025-Q1	304	186,500,166	95.2%	$6.5B
2024-Q4	263	176,688,384	90.2%	$4.8B
2024-Q3	254	174,030,594	88.9%	$4.4B
2024-Q2	251	175,145,273	89.4%	$4.4B

Short interest has its own tab now — open SI →

Source: SEC Form 13F — every institution manager (≥ $100M in 13F securities) reporting a long US-listed position, across ~10,250 filers over 10 years of history. 13F is long-only, US-listed, filed up to 45 days after quarter-end.

Activists & large holders· Schedule 13D/G beneficial owners · BBIO

Activists — 13D, active intent

KKR Genetic Disorder L.P.7%▼ -3.1ppSCHEDULE 13D/A · Amd 6 · event 2025-05-12SEC →

13,260,971 shares · 9 reporting persons

“Item 4 of the Schedule 13D is hereby amended and supplemented as follows: The information set forth in Item 5(c) below is incorporated by reference herein.”

VIKING GLOBAL INVESTORS LP5%▼ -1.1ppSCHEDULE 13D/A · Amd 12 · event 2026-07-09SEC →

9,792,219 shares · 7 reporting persons

“Item 4 of the Schedule 13D is hereby amended and supplemented as follows: The response to Item 5(c) of this Amendment No. 12 is incorporated by reference herein.”

Large holders — 13G, passive (top 5 of 6 by % of class)

Holder

% of class

Type

As of

JANUS HENDERSON GROUP PLC

6.8%

QII

2026-03-31

SEC →

Institutional ownership· 13F filers holding BBIO · 2026-Q1 methodology → sources →

457 holders

% of shares outstanding held

99.4%

Shares held (13F)

194,641,640

Reporting holders

457

Top holders

largest 100 of 457 · Δ vs 2025-Q4

#	Holder	Shares	Value	% of shares out	Δ QoQ
1	BlackRock, Inc.	14,207,75714.2M	$1.1B	7.25%	TRIM -2%
2	Kohlberg Kravis Roberts & Co. L.P.	13,260,97113.3M	$985M	6.77%	—
3	JANUS HENDERSON GROUP PLC	13,179,01313.2M	$979M	6.73%	ADD 20%
4	VIKING GLOBAL INVESTORS LPtracked	11,842,43411.8M	$879M	6.05%	TRIM -18%
5	FARALLON CAPITAL MANAGEMENT LLC	9,365,4639.4M	$695M	4.78%	ADD 4%
6	VANGUARD PORTFOLIO MANAGEMENT LLC	8,080,5738.1M	$600M	4.13%	NEW†
7	VANGUARD CAPITAL MANAGEMENT LLC	7,759,4957.8M	$576M	3.96%	NEW†
8	DIAMANT ASSET MANAGEMENT, INC.	527,246527,246	$527M	0.27%	NEW
9	Aisling Capital Management LP	5,089,6115.1M	$378M	2.60%	—
10	GEODE CAPITAL MANAGEMENT, LLC	4,918,0304.9M	$372M	2.51%	ADD 11%
11	STATE STREET CORP	4,934,3204.9M	$366M	2.52%	—
12	Invesco Ltd.	4,592,8144.6M	$341M	2.34%	TRIM -5%
13	PRICE T ROWE ASSOCIATES INC /MD/	3,801,6553.8M	$282M	1.94%	—
14	Frazier Life Sciences Management, L.P.	3,448,1393.4M	$256M	1.76%	TRIM -3%
15	CITADEL ADVISORS LLC	3,173,9403.2M	$236M	1.62%	ADD 355%
16	TWO SIGMA INVESTMENTS, LP	3,120,6313.1M	$232M	1.59%	ADD 60%
17	D. E. Shaw & Co., Inc.	2,545,4862.5M	$189M	1.30%	ADD 15%
18	Polar Capital Holdings Plc	2,519,3062.5M	$187M	1.29%	ADD 94%
19	WELLINGTON MANAGEMENT GROUP LLP	2,483,9532.5M	$184M	1.27%	ADD 6%
20	FRANKLIN RESOURCES INC	2,438,9252.4M	$181M	1.25%	ADD 13%
21	FMR LLC	2,343,7542.3M	$174M	1.20%	—
22	UBS Group AG	2,026,8212.0M	$151M	1.03%	ADD 8%
23	MANUFACTURERS LIFE INSURANCE COMPANY, THE	1,977,0802.0M	$147M	1.01%	—
24	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,976,0942.0M	$147M	1.01%	—
25	ALLIANCEBERNSTEIN L.P.	1,908,9071.9M	$146M	0.97%	TRIM -7%
26	GOLDMAN SACHS GROUP INC	1,897,7161.9M	$141M	0.97%	ADD 6%
27	MORGAN STANLEY	1,877,3591.9M	$139M	0.96%	ADD 34%
28	SC US (TTGP), LTD.	1,860,3641.9M	$138M	0.95%	—
29	JANE STREET GROUP, LLC	1,757,6721.8M	$131M	0.90%	ADD 414%
30	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	1,534,7361.5M	$114M	0.78%	TRIM -11%
31	NORTHERN TRUST CORP	1,403,6421.4M	$104M	0.72%	ADD 4%
32	Pictet Asset Management Holding SA	1,381,1841.4M	$101M	0.71%	ADD 9%
33	PRINCIPAL FINANCIAL GROUP INC	1,330,4151.3M	$99M	0.68%	—
34	BNP PARIBAS FINANCIAL MARKETS	1,307,1761.3M	$97M	0.67%	TRIM -18%
35	BANK OF AMERICA CORP /DE/	1,285,7481.3M	$95M	0.66%	ADD 19%
36	Hood River Capital Management LLC	1,265,0801.3M	$94M	0.65%	—
37	Laurion Capital Management LP	1,262,6511.3M	$94M	0.64%	TRIM -10%
38	AMERIPRISE FINANCIAL INC	1,248,5211.2M	$93M	0.64%	ADD 48%
39	JPMORGAN CHASE & CO	1,312,2591.3M	$91M	0.67%	ADD 53%
40	VANGUARD FIDUCIARY TRUST CO	1,175,1351.2M	$87M	0.60%	NEW
41	Driehaus Capital Management LLC	1,146,6711.1M	$85M	0.59%	TRIM -32%
42	AMERICAN CENTURY COMPANIES INC	1,090,3261.1M	$81M	0.56%	—
43	LORD, ABBETT & CO. LLC	1,023,3411.0M	$76M	0.52%	ADD 31%
44	GW&K Investment Management, LLC	962,643962,643	$71M	0.49%	ADD 54%
45	FRONTIER CAPITAL MANAGEMENT CO LLC	957,989957,989	$71M	0.49%	ADD 16%
46	Clearbridge Investments, LLC	951,200951,200	$71M	0.49%	ADD 91%
47	Allspring Global Investments Holdings, LLC	889,356889,356	$66M	0.45%	TRIM -11%
48	Cormorant Asset Management, LP	850,000850,000	$63M	0.43%	TRIM -29%
49	Deep Track Capital, LP	841,445841,445	$62M	0.43%	ADD 4%
50	Ensign Peak Advisors, Inc	836,552836,552	$62M	0.43%	TRIM -34%
51	Capital Research Global Investors	763,702763,702	$57M	0.39%	TRIM -61%
52	CITIGROUP INC	746,483746,483	$55M	0.38%	ADD 7%
53	PANAGORA ASSET MANAGEMENT INC	742,117742,117	$55M	0.38%	—
54	First Turn Management, LLC	695,718695,718	$52M	0.36%	ADD 17%
55	MILLENNIUM MANAGEMENT LLC	633,283633,283	$47M	0.32%	ADD 1631%
56	ADAGE CAPITAL PARTNERS GP, L.L.C.	599,000599,000	$44M	0.31%	ADD 18%
57	FEDERATED HERMES, INC.	588,434588,434	$44M	0.30%	—
58	Bank of New York Mellon Corp	577,283577,283	$43M	0.29%	TRIM -3%
59	PRIMECAP MANAGEMENT CO/CA/	569,180569,180	$42M	0.29%	—
60	Nuveen, LLC	562,696562,696	$42M	0.29%	ADD 14%
61	DIMENSIONAL FUND ADVISORS LP	561,945561,945	$42M	0.29%	ADD 47%
62	Squarepoint Ops LLC	556,324556,324	$41M	0.28%	ADD 107%
63	VOYA INVESTMENT MANAGEMENT LLC	538,980538,980	$40M	0.28%	TRIM -8%
64	EMERALD ADVISERS, LLC	515,361515,361	$38M	0.26%	TRIM -4%
65	EVENTIDE ASSET MANAGEMENT, LLC	437,130437,130	$32M	0.22%	ADD 21%
66	Catalio Capital Management, LP	432,014432,014	$32M	0.22%	NEW
67	VOLORIDGE INVESTMENT MANAGEMENT, LLC	426,583426,583	$32M	0.22%	TRIM -33%
68	BARCLAYS PLC	423,888423,888	$31M	0.22%	TRIM -32%
69	GILDER GAGNON HOWE & CO LLC	420,325420,325	$31M	0.21%	TRIM -8%
70	Sofinnova Investments, Inc.	409,183409,183	$30M	0.21%	TRIM -43%
71	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	402,948402,948	$30M	0.21%	TRIM -11%
72	SUSQUEHANNA INTERNATIONAL GROUP, LLP	398,943398,943	$30M	0.20%	TRIM -18%
73	RENAISSANCE TECHNOLOGIES LLC	365,772365,772	$27M	0.19%	NEW
74	1832 Asset Management L.P.	356,400356,400	$26M	0.18%	ADD 682%
75	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	352,831352,831	$26M	0.18%	TRIM -57%
76	Russell Investments Group, Ltd.	351,719351,719	$26M	0.18%	TRIM -15%
77	Fisher Asset Management, LLC	351,628351,628	$26M	0.18%	ADD 51%
78	Balyasny Asset Management L.P.	350,096350,096	$26M	0.18%	ADD 49%
79	FIRST TRUST ADVISORS LP	339,907339,907	$25M	0.17%	ADD 21%
80	MARSHALL WACE, LLP	334,382334,382	$25M	0.17%	ADD 348%
81	Fiera Capital Corp	322,690322,690	$24M	0.16%	NEW
82	EMERALD MUTUAL FUND ADVISERS TRUST	320,211320,211	$24M	0.16%	—
83	NOMURA HOLDINGS INC	318,563318,563	$24M	0.16%	ADD 3%
84	Woodline Partners LP	301,012301,012	$22M	0.15%	—
85	RAYMOND JAMES FINANCIAL INC	311,959311,959	$22M	0.16%	ADD 165%
86	Nicholas Investment Partners, LP	298,909298,909	$22M	0.15%	ADD 5%
87	DEUTSCHE BANK AG\	296,683296,683	$22M	0.15%	TRIM -22%
88	SEI INVESTMENTS CO	288,075288,075	$21M	0.15%	ADD 28%
89	Swiss National Bank	286,000286,000	$21M	0.15%	—
90	Legal & General Group Plc	284,917284,917	$21M	0.15%	TRIM -15%
91	ALGERT GLOBAL LLC	283,921283,921	$21M	0.14%	TRIM -17%
92	Candriam S.C.A.	278,888278,888	$21M	0.14%	—
93	Integral Health Asset Management, LLC	275,000275,000	$20M	0.14%	NEW
94	Eagle Health Investments LP	267,031267,031	$20M	0.14%	ADD 3%
95	Bridgewater Associates, LP	259,459259,459	$19M	0.13%	ADD 501%
96	PFM Health Sciences, LP	257,747257,747	$19M	0.13%	TRIM -16%
97	Artisan Partners Limited Partnership	254,392254,392	$19M	0.13%	TRIM -9%
98	VICTORY CAPITAL MANAGEMENT INC	254,007254,007	$19M	0.13%	TRIM -8%
99	California Public Employees Retirement System	253,479253,479	$19M	0.13%	ADD 22%
100	SPHERA FUNDS MANAGEMENT LTD.	245,246245,246	$18M	0.13%	ADD 128%

† a filer this large appearing as NEW usually reflects a renamed or succeeded filing entity (the old name stops filing the same quarter) — not a brand-new position.

Rows rank by the value each filer reported — 13F filers price their own positions, so a holder with fewer shares can rank just above one with more.

Holder trends· top 15 holders · shares held over 6 quarters

green added · red trimmed

Holder

2024-Q4

2025-Q1

2025-Q2

2025-Q3

2025-Q4

2026-Q1

Latest value

BlackRock, Inc.

13.7M

13.4M

14.3M

14.4M

14.5M

14.2M

$1.1B

Kohlberg Kravis Roberts & Co. L.P.

25.3M

19.3M

13.3M

$985M

JANUS HENDERSON GROUP PLC

4.9M

7.2M

9.3M

8.7M

11.0M

13.2M

$979M

VIKING GLOBAL INVESTORS LPtracked

25.1M

22.1M

18.6M

16.0M

14.4M

11.8M

$879M

FARALLON CAPITAL MANAGEMENT LLC

4.2M

5.7M

7.9M

8.2M

9.0M

9.4M

$695M

VANGUARD PORTFOLIO MANAGEMENT LLC

—

8.1M

$600M

VANGUARD CAPITAL MANAGEMENT LLC

—

7.8M

$576M

DIAMANT ASSET MANAGEMENT, INC.

—

527K

$527M

Aisling Capital Management LP

6.1M

5.1M

$378M

GEODE CAPITAL MANAGEMENT, LLC

3.4M

3.5M

3.7M

3.9M

4.4M

4.9M

$372M

STATE STREET CORP

6.2M

5.7M

5.9M

5.6M

5.0M

4.9M

$366M

Invesco Ltd.

893K

2.2M

2.8M

3.9M

4.8M

4.6M

$341M

PRICE T ROWE ASSOCIATES INC /MD/

991K

1.2M

961K

1.6M

3.8M

$282M

Frazier Life Sciences Management, L.P.

3.8M

3.5M

3.4M

$256M

CITADEL ADVISORS LLC

1.3M

2.9M

332K

—

698K

3.2M

$236M

Institutional footprint by quarter

Line breaks are honest gaps — quarters with no 13F record, or a suppressed % — never interpolated. % of shares outstanding uses today's share count for every quarter (the only count stored).

Quarter	Holders	Shares held	% shares out	Value held
2026-Q1	457	194,641,640	99.4%	$14.9B
2025-Q4	432	191,094,399	97.6%	$14.4B
2025-Q3	393	185,445,803	94.7%	$9.6B
2025-Q2	360	189,033,467	96.5%	$8.2B
2025-Q1	304	186,500,166	95.2%	$6.5B
2024-Q4	263	176,688,384	90.2%	$4.8B
2024-Q3	254	174,030,594	88.9%	$4.4B
2024-Q2	251	175,145,273	89.4%	$4.4B

Short interest has its own tab now — open SI →

Activists & large holders· Schedule 13D/G beneficial owners · BBIO

Activists — 13D, active intent

KKR Genetic Disorder L.P.7%▼ -3.1ppSCHEDULE 13D/A · Amd 6 · event 2025-05-12SEC →

13,260,971 shares · 9 reporting persons

“Item 4 of the Schedule 13D is hereby amended and supplemented as follows: The information set forth in Item 5(c) below is incorporated by reference herein.”

VIKING GLOBAL INVESTORS LP5%▼ -1.1ppSCHEDULE 13D/A · Amd 12 · event 2026-07-09SEC →

9,792,219 shares · 7 reporting persons

“Item 4 of the Schedule 13D is hereby amended and supplemented as follows: The response to Item 5(c) of this Amendment No. 12 is incorporated by reference herein.”

Large holders — 13G, passive (top 5 of 6 by % of class)

Holder

% of class

Type

As of

JANUS HENDERSON GROUP PLC

6.8%

QII

2026-03-31

SEC →

BBIO US Equity☆

Institutional ownership· 13F filers holding BBIO · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · BBIO

Institutional ownership· 13F filers holding BBIO · 2026-Q1 methodology → sources →

Top holders

Holder trends· top 15 holders · shares held over 6 quarters

Institutional footprint by quarter

Activists & large holders· Schedule 13D/G beneficial owners · BBIO

BBIO US Equity