Only open-market buys / sells (codes P/S) are a conviction signal; grants, option exercises, tax-withholding, and gifts are compensation mechanics, shown but greyed. The trailing 12-month tallies run to today but the store covers filings through 2026-06-30 only (SEC bulk data sets publish quarterly), so recent activity may be absent.
| Date | Insider | Role | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 2026-05-22 | Drappa Jorn | Officer | +Exercise | 11,317 | $8.84 | $100,042 |
| 2026-05-22 | Drappa Jorn | Officer | +Exercise | 15,535 | $5.06 | $78,607 |
| 2026-04-01 | Tananbaum James B. | Director,TenPercentOwner | +Other | 1,123,337 | — | — |
| 2026-04-01 | Tananbaum James B. | Director,TenPercentOwner | −Other | 1,176,470 | — | — |
| 2026-04-01 | Tananbaum James B. | Director,TenPercentOwner | −Other | 1,123,337 | — | — |
| 2026-04-01 | Tananbaum James B. | Director,TenPercentOwner | +Other | 680,486 | — | — |
| 2026-04-01 | Foresite Capital Management VI LLC | TenPercentOwner | +Other | 1,123,337 | — | — |
| 2026-04-01 | Foresite Capital Management VI LLC | TenPercentOwner | +Other | 680,486 | — | — |
| 2026-04-01 | Foresite Capital Management VI LLC | TenPercentOwner | −Other | 1,123,337 | — | — |
| 2026-04-01 | Foresite Capital Management VI LLC | TenPercentOwner | −Other | 1,176,470 | — | — |
| 2026-04-01 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | −Other | 1,123,337 | — | — |
| 2026-04-01 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | −Other | 1,176,470 | — | — |
| 2026-04-01 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Other | 680,486 | — | — |
| 2026-04-01 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Other | 1,123,337 | — | — |
| 2026-01-09 | AKKARAJU SRINIVAS | Director | +Buy | 588,235 | $17.00 | $10M |
| 2026-01-08 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 117,647 | $17.00 | $2M |
| 2026-01-08 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 294,117 | $17.00 | $5M |
| 2026-01-08 | Foresite Labs Fund I, L.P. | TenPercentOwner | +Buy | 294,117 | $17.00 | $5M |
| 2026-01-08 | Foresite Labs Fund I, L.P. | TenPercentOwner | +Buy | 117,647 | $17.00 | $2M |
| 2026-01-08 | Foresite Labs, LLC | TenPercentOwner | +Buy | 294,117 | $17.00 | $5M |
| 2026-01-08 | Foresite Labs, LLC | TenPercentOwner | +Buy | 117,647 | $17.00 | $2M |
| 2025-12-05 | AKKARAJU SRINIVAS | Director | +Buy | 64,969 | $8.95 | $581,473 |
| 2025-12-05 | AKKARAJU SRINIVAS | Director | +Buy | 51,380 | $10.73 | $551,307 |
| 2025-12-05 | AKKARAJU SRINIVAS | Director | +Buy | 70,028 | $10.01 | $700,980 |
| 2025-12-04 | AKKARAJU SRINIVAS | Director | +Buy | 66,027 | $8.18 | $540,101 |
| 2025-12-03 | AKKARAJU SRINIVAS | Director | +Buy | 100,000 | $7.75 | $775,000 |
| 2025-12-02 | AKKARAJU SRINIVAS | Director | +Buy | 96,000 | $7.55 | $724,800 |
| 2025-12-01 | AKKARAJU SRINIVAS | Director | +Buy | 86,350 | $7.46 | $644,171 |
| 2025-11-28 | AKKARAJU SRINIVAS | Director | +Buy | 38,702 | $7.64 | $295,683 |
| 2025-11-26 | AKKARAJU SRINIVAS | Director | +Buy | 48,537 | $7.64 | $370,823 |
| 2025-11-21 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 72,212 | $7.38 | $532,925 |
| 2025-11-21 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 72,212 | $7.38 | $532,925 |
| 2025-11-21 | Foresite Labs Fund I, L.P. | TenPercentOwner | +Buy | 72,212 | $7.38 | $532,925 |
| 2025-11-20 | AKKARAJU SRINIVAS | Director | +Buy | 125,743 | $7.20 | $905,350 |
| 2025-11-19 | AKKARAJU SRINIVAS | Director | +Buy | 137,772 | $6.56 | $903,784 |
| 2025-11-19 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 190,500 | $6.56 | $1M |
| 2025-11-19 | Foresite Capital Management VI LLC | TenPercentOwner | +Buy | 190,500 | $6.56 | $1M |
| 2025-11-19 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 190,500 | $6.56 | $1M |
| 2025-11-18 | AKKARAJU SRINIVAS | Director | +Buy | 102,652 | $6.05 | $621,045 |
| 2025-11-18 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 117,374 | $6.19 | $726,545 |
| 2025-11-18 | Foresite Capital Management VI LLC | TenPercentOwner | +Buy | 117,374 | $6.19 | $726,545 |
| 2025-11-18 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 117,374 | $6.19 | $726,545 |
| 2025-11-17 | AKKARAJU SRINIVAS | Director | +Buy | 914 | $5.51 | $5,036 |
| 2025-11-17 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 50,000 | $5.60 | $280,000 |
| 2025-11-17 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 150,000 | $5.59 | $838,500 |
| 2025-11-17 | Foresite Capital Management VI LLC | TenPercentOwner | +Buy | 150,000 | $5.59 | $838,500 |
| 2025-11-17 | Foresite Capital Management VI LLC | TenPercentOwner | +Buy | 50,000 | $5.60 | $280,000 |
| 2025-11-17 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 150,000 | $5.59 | $838,500 |
| 2025-11-17 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 50,000 | $5.60 | $280,000 |
| 2025-11-13 | AKKARAJU SRINIVAS | Director | +Buy | 276,179 | $5.25 | $1M |
| 2025-09-25 | Goldstein David M | Officer | −Inherited | 1,000 | — | — |
| 2025-07-29 | Bradley Mark Christopher | Officer | +Grant | 26,750 | — | — |
| 2025-07-29 | Drappa Jorn | Officer | +Grant | 25,450 | — | — |
| 2025-07-29 | Goldstein David M | Officer | +Grant | 27,000 | — | — |
| 2025-07-29 | Hardiman Roy C. | Officer | +Grant | 28,000 | — | — |
| 2025-07-29 | Schroer John R. | Officer | +Grant | 28,000 | — | — |
| 2025-07-29 | Richardson Derrick | Officer | +Grant | 42,800 | — | — |
| 2025-07-29 | Pangali Sanam | Officer | +Grant | 10,000 | — | — |
| 2025-05-21 | Machado Patrick | Director | +Grant | 7,064 | — | — |
| 2025-05-21 | AyurMaya Capital Management Company, LP | Director,TenPercentOwner,Other | +Grant | 4,493,741 | — | — |
| 2025-05-21 | AKKARAJU SRINIVAS | Director | +Grant | 1,214,582 | — | — |
| 2025-05-06 | Foresite Labs Management I, LLC | TenPercentOwner | +Buy | 20,000 | $4.34 | $86,800 |
| 2025-05-06 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 20,000 | $4.34 | $86,800 |
| 2025-05-06 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 20,000 | $4.34 | $86,800 |
| 2025-05-05 | AKKARAJU SRINIVAS | Director | +Buy | 138,368 | $4.58 | $633,725 |
| 2025-05-05 | AKKARAJU SRINIVAS | Director | +Buy | 22,002 | $5.27 | $115,951 |
| 2025-05-02 | AKKARAJU SRINIVAS | Director | +Buy | 159,920 | $4.55 | $727,636 |
| 2025-05-02 | Foresite Labs Management I, LLC | TenPercentOwner | +Buy | 25,000 | $4.62 | $115,500 |
| 2025-05-02 | Foresite Labs Affiliates 2021, LLC | TenPercentOwner | +Buy | 25,000 | $4.62 | $115,500 |
| 2025-05-02 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 25,000 | $4.62 | $115,500 |
| 2025-04-02 | Colowick Alan | Director | +Buy | 2,300 | $7.49 | $17,227 |
| 2025-04-01 | Babler Martin | Director,Officer | +Buy | 15,650 | $6.44 | $100,786 |
| 2025-04-01 | Colowick Alan | Director | +Buy | 16,104 | $6.97 | $112,245 |
| 2024-07-01 | Babler Martin | Director,Officer | −Disp→issuer | 90,804 | — | — |
| 2024-07-01 | Babler Martin | Director,Officer | +Grant | 90,804 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | +Grant | 20,026 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | +Grant | 21,978 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | −Disp→issuer | 20,026 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | +Grant | 20,026 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | −Disp→issuer | 20,026 | — | — |
| 2024-07-01 | Bradley Mark Christopher | Officer | −Disp→issuer | 21,978 | — | — |
| 2024-07-01 | Goldstein David M | Officer | −Disp→issuer | 213,903 | — | — |
| 2024-07-01 | Goldstein David M | Officer | +Grant | 213,903 | — | — |
| 2024-07-01 | Goldstein David M | Officer | −Disp→issuer | 2,994 | — | — |
| 2024-07-01 | Goldstein David M | Officer | +Grant | 2,994 | — | — |
| 2024-07-01 | Hardiman Roy C. | Officer | +Grant | 175,401 | — | — |
| 2024-07-01 | Hardiman Roy C. | Officer | +Grant | 6,417 | — | — |
| 2024-07-01 | Hardiman Roy C. | Officer | −Disp→issuer | 6,417 | — | — |
| 2024-07-01 | Hardiman Roy C. | Officer | −Disp→issuer | 175,401 | — | — |
| 2024-07-01 | Klein Sara | Officer | +Grant | 33,796 | — | — |
| 2024-07-01 | Klein Sara | Officer | −Disp→issuer | 33,796 | — | — |
| 2024-07-01 | AKKARAJU SRINIVAS | Director | −Disp→issuer | 1,703,998 | — | — |
| 2024-07-01 | AKKARAJU SRINIVAS | Director | +Grant | 1,703,998 | — | — |
| 2024-07-01 | AKKARAJU SRINIVAS | Director | +Conversion | 1,703,998 | — | — |
| 2024-07-01 | Yao Zhengbin | Director | −Disp→issuer | 23,529 | — | — |
| 2024-07-01 | Yao Zhengbin | Director | +Grant | 23,529 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 622,344 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 1,122,994 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 2,187,500 | $16.00 | $35M |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 1,703,998 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 311,172 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 681,598 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 311,172 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 967,567 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 681,598 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 311,172 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 560,076 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 481,283 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 194,459 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Buy | 312,500 | $16.00 | $5M |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 1,022,398 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 1,944,577 | — | — |
| 2024-07-01 | Tananbaum James B. | Director,TenPercentOwner | +Conversion | 560,076 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 1,122,994 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 622,344 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 1,022,398 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Buy | 312,500 | $16.00 | $5M |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 194,459 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 481,283 | — | — |
| 2024-07-01 | Foresite Capital Opportunity Management V, LLC | TenPercentOwner | +Conversion | 560,076 | — | — |
Source: the SEC bulk insider (Form 3/4/5) data sets — non-derivative transactions in the issuer's common stock, most recent first, covering filings through 2026-06-30. Insiders file within 2 business days of a transaction, but the bulk sets publish quarterly, so this store lags live filings; option/derivative lines are excluded. Codes: P buy · S sell · A grant · M/X/C exercise · F tax · G gift.
Model-derived estimate for research. See the Disclaimer.
