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Clinical trials
catalyst calendar across sponsors →Studies where AAPL is the lead sponsor, as filed with ClinicalTrials.gov. Completion dates are the sponsor's own projected windows and are revised as a study runs. Active studies first, then completed and stopped — newest readout first within each.
6 interventional · 6 observational · 6 with posted results
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| Study | Phase | Status | Interventions | Conditions | Enrollment | Primary completion | Readout in | Updated |
|---|---|---|---|---|---|---|---|---|
| Apple Health StudyNCT06958523observationalHealth Status | — | Recruiting | — | Mental Health, Sleep, Exercise, Hormones, Metabolic Health, Hearing, Aging, Lifestyle Factors, Functional Capacity, Neurological Conditions, General Health, Wellbeing, Women's Health | 500,000 | Feb 2030 | ≤ 1,289 d | 2025-07-29 |
| Apple Women's Health StudyNCT04196595observationalIdentify Menstrual Cycle Patterns | — | Recruiting | — | Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome, Infertility, Menopause, Reproduction, Reproductive Health | 500,000 | Nov 2029 | ≤ 1,199 d | 2024-07-03 |
| Apple Hearing StudyNCT04172766observationalHeadphone audio level patterns | — | Active, not recruiting | — | Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus | 300,000 | 2029-08-31 | in 1,108 d | 2026-03-19 |
| Apple Heart & Movement StudyNCT04198194observationalNumber of Participants with Chronic Disease Events | — | Active, not recruiting | Diagnostic test: Predictors of events | Prevention | 500,000 | 2025-02-28 | — | 2025-02-21 |
| Smartphone Enabled Hearing StudyNCT05872035results2024-10-29International Outcome Inventory for Hearing Aids (IOI-HA) Survey ResultsRandomized · Open-label · TreatmentStudy Protocol ↗ · Statistical Analysis Plan ↗ | Not applicable | Completed | Device: Apple Software, by Audiologist | Hearing | 118 | 2023-08-17actual | — | 2024-10-29 |
| Cycle and Ovulation Study ExpansionNCT05852951observationalRetrospective ovulation day estimate | — | Completed | — | Menstruation | 698 | 2022-05-23actual | — | 2023-05-10 |
| Apple Respiratory StudyNCT04912180observationalSymptomatic individuals that self-report ARI and have a laboratory-confirmed positive test for SARS-CoV-2 and/or influenza within 72 hours | — | Terminatedsponsor's stated reason: Study endpoints no longer feasible. | — | Acute Respiratory Infection, Coronavirus Infection, Influenza | 108 | 2021-06-09actual | — | 2021-07-14 |
| Atrial Fibrillation Algorithms Clinical Validation StudyNCT04699812results2022-08-24SENSITIVITY OF IRREGULAR RHYTHM NOTIFICATION FEATURE [IRNF]Non-randomized · Open-label · ScreeningStudy Protocol and Statistical Analysis Plan ↗ | Not applicable | Completed | Device: ELECTROCARDIOGRAM (ECG) PATCH WEAR | Atrial Fibrillation | 573 | 2021-04-19actual | — | 2022-08-24 |
| ECG App Algorithms Clinical Validation StudyNCT04247581results2021-09-28Percentage of Trials With Correct Classification of Normal Sinus Rhythm on Simultaneous 12-lead ECG as "Sinus Rhythm" or "High Heart Rate" on a Readable and Classifiable ECG App Strip.Non-randomized · Open-label · ScreeningStudy Protocol ↗ · Statistical Analysis Plan ↗ | Not applicable | Completed | Device: 1-lead ECG | Atrial Fibrillation | 546 | 2020-03-20actual | — | 2021-09-28 |
| Evaluation of the Use of Apple Watch Features for Identification of Cardiac ArrhythmiasNCT03769207results2020-10-20Atrial Fibrillation or Atrial Flutter (AF) of at Least 30 Seconds DurationOpen-label · OtherStudy Protocol and Statistical Analysis Plan ↗ | Not applicable | Completed | Device: Ambulatory ECG | Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter | 17 | 2019-07-05actual | — | 2020-10-20 |
| Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac ArrhythmiasNCT03335800results2020-03-30Atrial Fibrillation (AF) of Greater Than 30 SecondsOpen-label · ScreeningStudy Protocol and Statistical Analysis Plan ↗ | Not applicable | Completed | Device: Apple Heart Study App | Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter | 419,927 | 2019-02-21actual | — | 2020-03-30 |
| Electrocardiogram Clinical Validation StudyNCT03492554results2019-07-24Number of Participants With Software's Rhythm Classification of SR in Agreement to a Physician's Interpretation of a Gold Standard 12-lead ECGNon-randomized · Open-label · Basic scienceStudy Protocol and Statistical Analysis Plan ↗ | Not applicable | Completed | Other: 1-Lead ECG · Device: 12-Lead ECG | Atrial Fibrillation | 602 | 2018-05-14actual | — | 2020-12-03 |
Primary completion is the date the sponsor filed with the registry — their own projection, revised whenever they revise it, unless the row is marked actual.
Source: ClinicalTrials.gov, retrieved 2026-08-19