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A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema

← catalyst calendar

NCT07783425 · readout in 735 d

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
1,375estimated
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-24

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-19estimatedWhen the study began enrolling
Primary completion2028-08-29estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-06-05estimatedThe whole study's end, after follow-up
First posted2026-08-24actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Atopic Dermatitis

Interventions

  • Drug: Tilrekimig — also filed as PF-07275315
  • Drug: Dupilumab — also filed as Dupixent
  • Other: Placebo for Tilrekimig — also filed as Placebo for PF-07275315
  • Other: Placebo for Dupilumab

Primary outcomes

what the primary-completion date above is the date OF
Difference in the proportion of Eczema Area and Severity Index (EASI)75 responders between tilrekimig versus placebo.
measured Week 16
Difference in the proportion of validated Investigator Global Assessment- Atopic Dermatitis (vIGA-AD) 0/1 responders between tilrekimig versus placebo.
measured Week 16

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