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An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease

← catalyst calendar

NCT07764146 · readout in 983 d

Sponsored by Voyager Therapeutics (industry) · VYGR — their whole pipeline →.

Phase
Phase 1
Status
Not yet recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
18estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-24estimatedWhen the study began enrolling
Primary completion2029-04-28estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-04-28estimatedThe whole study's end, after follow-up
First posted2026-08-13actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-13actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Alzheimer s Disease

Interventions

  • Drug: VY1706 Low dose
  • Drug: VY1706 Mid dose
  • Drug: VY1706 High Dose
  • Device: Anti-AAV9 Total Antibody (TAb) Assay

Primary outcome

what the primary-completion date above is the date OF
To characterize the safety and tolerability in participants with AD by Incidence of treatment emergent adverse events, changes from baseline in vital signs, physical and neurological exams and other safety measures
measured 52 weeks

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