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Study of 3 Monoclonal Antibodies (REGN9933, REGN7508, and REGN9533) in Adult Participants With End-Stage Kidney Disease on Hemodialysis

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NCT07759167 · readout in 218 d

Sponsored by Regeneron Pharmaceuticals (industry) · REGN — their whole pipeline →.

Phase
Phase 1
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
36estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-09-09estimatedWhen the study began enrolling
Primary completion2027-03-25estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-03-25estimatedThe whole study's end, after follow-up
First posted2026-08-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-12actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • End-Stage Kidney Disease (ESKD)

Interventions

  • Drug: REGN9933 — also filed as amrecibart
  • Drug: REGN7508 — also filed as cenvacibart
  • Drug: REGN9533
  • Drug: Heparin

Primary outcomes

what the primary-completion date above is the date OF
Occurrence of Treatment-Emergent Adverse Events (TEAEs)
measured Up to approximately 78 days
Severity of TEAEs
measured Up to approximately 78 days

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