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Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

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NCT07745361 · readout ≤ 438 d

Sponsored by Monte Rosa Therapeutics, Inc (industry) · GLUE — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
25estimated
Sites
14
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
StartAug 2026estimatedWhen the study began enrolling
Primary completionOct 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionApr 2028estimatedThe whole study's end, after follow-up
First posted2026-08-04actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-04actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Castration-Resistant Prostate Cancer (CRPC)
  • Castration-Resistant Prostate Cancer
  • Prostate Cancer
  • Prostate Cancer (Adenocarcinoma)

Interventions

  • Drug: Oral MRT-2359
  • Drug: Apalutamide

Primary outcome

what the primary-completion date above is the date OF
Assess the efficacy of MRT-2359 combined with apalutamide
measured 14 months

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