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Study on the Effect of Famotidine on Pharmacokinetics of Taletrectinib

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NCT07742384 · readout in 167 d

Sponsored by Nuvation Bio Inc. (industry) · NUVB — their whole pipeline →.

Phase
Phase 1
Status
Not yet recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
56estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-01estimatedWhen the study began enrolling
Primary completion2027-02-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-02-02estimatedThe whole study's end, after follow-up
First posted2026-08-03actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-03actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Adult Participants

Interventions

  • Drug: Taletrectinib
  • Drug: Taletrectinib, Famotidine
  • Drug: Taletrectinib, Famotidine
  • Drug: Taletrectinib
  • Drug: Taletrectinib, Famotidine
  • Drug: Taletrectinib,Famotidine

Primary outcomes

what the primary-completion date above is the date OF
Cmax of Taletrectinib
measured Pre-dose to 264 hours post dose on Day 1, Day 15 and Day 30
AUClast of Taletrectinib
measured Pre-dose to 264 hours post dose on Day 1, Day 15 and Day 30
AUCinf of Taletrectinib
measured Pre-dose to 264 hours post dose on Day 1, Day 15 and Day 30

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