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A Study of DS-3939a in Participants With Solid Tumors

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NCT07739966 · readout in 1,442 d

Sponsored by Daiichi Sankyo (industry) · 4568.T — their whole pipeline →.

Phase
Phase 1/2
Status
Not yet recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
400estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-10-01estimatedWhen the study began enrolling
Primary completion2030-07-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2032-01-29estimatedThe whole study's end, after follow-up
First posted2026-07-31actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-31actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Solid Tumor
  • Locally Advanced Non-Small Cell Lung Cancer
  • Metastatic Non-Small Cell Lung Cancer

Interventions

  • Drug: DS-3939a
  • Drug: Pembrolizumab — also filed as MK-3475
  • Drug: Carboplatin
  • Drug: Pemetrexed
  • Drug: DS-1103a

Primary outcomes

what the primary-completion date above is the date OF
Part 1: Number of Participants With Dose-limiting Toxicities (DLTs)
measured During first cycle (Cycle length=21 days)
Part 1: Number of Participants With TEAEs
measured Up to approximately 4 years
Part 2: Objective Response (OR) Per RECIST v1.1 as Assessed by Investigator
measured Up to approximately 4 years

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