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A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).

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NCT07735637 · readout in 784 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
750estimated
Sites
65
Countries
Australia, Brazil, Canada +12

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-25estimatedWhen the study began enrolling
Primary completion2028-10-11estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2039-11-09estimatedThe whole study's end, after follow-up
First posted2026-07-30actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-30actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Newly Diagnosed Multiple Myeloma (NDMM)

Interventions

  • Biological: AZD0120
  • Drug: Cyclophosphamide
  • Drug: Fludarabine
  • Drug: Melphalan (part of ASCT)
  • Drug: Lenalidomide

Primary outcomes

what the primary-completion date above is the date OF
Progression-Free Survival (PFS)
measured Up to approximately 13 years.
Minimal Residual Disease (MRD) negative Complete Response Rate (CRR)
measured Up to approximately 13 years.

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