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A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma

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NCT07728188 · readout ≤ 2,385 d

Sponsored by AbbVie (industry) · ABBV — their whole pipeline →.

Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
520estimated
Sites
66
Countries
Australia, Canada, France +10

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-11-30estimatedWhen the study began enrolling
Primary completionFeb 2033estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionFeb 2033estimatedThe whole study's end, after follow-up
First posted2026-07-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-27actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Relapsed or Refractory Multiple Myeloma

Interventions

  • Drug: Etentamig
  • Drug: Pomalidomide
  • Drug: Daratumumab
  • Drug: Dexamethasone
  • Drug: Carfilzomib
  • Drug: Teclistamab

Primary outcomes

what the primary-completion date above is the date OF
Safety Run-In: Number of Participants With Adverse Events (AE)s
measured Up to Approximately 75 Months
Randomized Portion: Complete Response (CR) or Better Rate Per Independent Review Committee (IRC) Assessment
measured Up to Approximately 75 Months
Randomized Portion: Progression-Free Survival (PFS) Per Independent Review Committee (IRC) Assessment
measured Up to Approximately 75 Months

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