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Phase 4 Master Protocol for Patients Prescribed Prademagene Zamikeracel for the Treatment of Wounds

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NCT07717736 · readout ≤ 1,929 d

Sponsored by Abeona Therapeutics, Inc (industry) · ABEO — their whole pipeline →.

Phase
Phase 4
Status
Not yet recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
100estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
StartNov 2026estimatedWhen the study began enrolling
Primary completionNov 2031estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJul 2032estimatedThe whole study's end, after follow-up
First posted2026-07-21actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Epidermolysis Bullosa (EB)
  • Recessive Dystrophic Epidermolysis Bullosa (RDEB)
  • Dystrophic Epidermolysis Bullosa (DEB)

Interventions

  • Biological: Non-conforming pz-cel surgical application to RDEB wounds
  • Procedure: Additional biopsies
  • Biological: Pz-cel surgical application to DEB wounds

Primary outcomes

what the primary-completion date above is the date OF
Study A - Wound Healing ≥50%
measured From Baseline at Week 24 (Month 6)
Study A - Pain Severity Scale (Wong-Baker FACES)
measured At Week 24 (Month 6)
Study C - Wound Healing ≥50%
measured From Baseline at Week 24 (Month 6)
Study C - Pain Severity Scale (Wong-Baker FACES)
measured At Week 24 (Month 6)

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