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A Study to Investigate the Relative Bioavailability of 2 Tablet Formulations and the Effect of Food on the Pharmacokinetics of BGB-58067 in Healthy Participants

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NCT07712640 · readout in 316 d

Sponsored by BeOne Medicines (industry) · ONC — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
32estimated
Sites
1
Country
Australia

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-07-21actualWhen the study began enrolling
Primary completion2027-07-01estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-07-01estimatedThe whole study's end, after follow-up
First posted2026-07-17actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Volunteers

Interventions

  • Drug: BGB-58067 Tablet (F-01 Formulation)
  • Drug: BGB-58067 Tablet (F-02 Formulation)

Primary outcomes

what the primary-completion date above is the date OF
Area under the Plasma Concentration-Time Curve from Time 0 Infinity (AUC0-inf) for BGB-58067
measured Approximately 4 Days
Area under the Plasma Concentration-Time Curve from Time 0 to the Time of the Last Quantifiable Concentration (AUC0-t last) for BGB-58067
measured Approximately 4 Days
Maximum Observed Plasma Concentration (Cmax) of BGB-58067
measured Approximately 4 Days
Time of the Maximum Observed Concentration (Tmax) for BGB-58067
measured Approximately 4 Days
Apparent Terminal Elimination Half-life (t1/2) for BGB-58067
measured Approximately 4 Days
Apparent Total Clearance from Plasma after Oral Administration (CL/F) for BGB-58067
measured Approximately 4 Days
Apparent Volume of Distribution at Steady State after Extravascular Administration (Vz/F) for BGB-58067
measured Approximately 4 Days

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