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Phase 2 Study of 500 mg BID NTZ on Top of Standard of Care in Patients With Acute Decompensation of Liver Cirrhosis at High Risk of Progression to Acute-on-Chronic Liver Failure or Established Acute-on-Chronic Liver Failure

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NCT07694297 · readout ≤ 377 d

Sponsored by Genfit (industry) · GNFT.PA — their whole pipeline →.

Phase
Phase 2
Status
Not yet recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
16estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
StartOct 2026estimatedWhen the study began enrolling
Primary completionAug 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionDec 2027estimatedThe whole study's end, after follow-up
First posted2026-07-09actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-09actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Acute Decompensation of Liver Cirrhosis
  • Established Acute-on-Chronic Liver Failure

Intervention

  • Drug: NTZ 500mg BID on top of SOC

Primary outcome

what the primary-completion date above is the date OF
To evaluate the safety of 500 mg BID NTZ administered perorally
measured over 7 days on top of SOC follow-up period up to Day 28.

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