First-in-Human Trial of DS1025a in Participants With Advanced Solid Tumors
← catalyst calendarNCT07681882 · readout in 520 d
Sponsored by Daiichi Sankyo (industry) · 4568.T — their whole pipeline →.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
45estimated
Sites
2
Country
Japan
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-08-06 | actual | When the study began enrolling |
| Primary completion | 2028-01-21 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2029-01-21 | estimated | The whole study's end, after follow-up |
| First posted | 2026-07-02 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-10 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Advanced Solid Tumor
- Metastatic Solid Tumor
- Unresectable Solid Tumor
Intervention
- Drug: DS1025a
Primary outcomes
what the primary-completion date above is the date OFNumber of Participants Reporting Dose-limiting Toxicities (DLTs)
measured Day 1 up to approximately 12 months
Number of Participants Reporting Adverse Events (AEs)
measured Screening up to long-term survival follow up every 12 weeks, up to approximately 12 months
Number of Participants Reporting Discontinuation of DS1025a Due to AEs
measured Screening up to long-term survival follow up every 12 weeks, up to approximately 12 months
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