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A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

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NCT07680764 · readout in 758 d

Sponsored by Bristol-Myers Squibb (industry) · BMY — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
160estimated
Sites
71
Countries
Argentina, Australia, Brazil +9

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-15estimatedWhen the study began enrolling
Primary completion2028-09-15estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-09-15estimatedThe whole study's end, after follow-up
First posted2026-07-02actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
  • Metastatic Non-Small Cell Lung Cancer (NSCLC)

Interventions

  • Drug: Pumitamig — also filed as BMS-986545, BNT327, PM8002
  • Drug: Imzokitug — also filed as Anti-CCR8, BMS-986340

Primary outcome

what the primary-completion date above is the date OF
Objective response rate (ORR) by investigator (per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1)
measured Up to approximately 4 years

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