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Study to Assess How Different Oral Formulations of Ubrogepant Move Through the Body in Healthy Adult Participants

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NCT07680686 · readout ≤ 73 d

Sponsored by AbbVie (industry) · ABBV — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Basic science
Enrollment
52estimated
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-07-14actualWhen the study began enrolling
Primary completionOct 2026estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionOct 2026estimatedThe whole study's end, after follow-up
First posted2026-07-02actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy Volunteer

Interventions

  • Drug: Ubrogepant
  • Drug: Ubrogepant

Primary outcomes

what the primary-completion date above is the date OF
Number of Participants Experiencing Adverse Events
measured Up to approximately 33 days
Area under the plasma concentration-time curve from time 0 until the last measurable concentration (AUCt) of Ubrogepant
measured Up to approximately 3 days
AUC From Time 0 to the Time Infinity (AUCinf) of Ubrogepant
measured Up to approximately 3 days
Maximum Observed Plasma Concentration (Cmax) of Ubrogepant
measured Up to approximately 3 days
Time lag between dosing and drug to appear in systemic circulation following extravascular administration (Tlag) of Ubrogepant
measured Up to approximately 3 days
Time to maximum observed plasma concentration (Tmax) of Ubrogepant
measured Up to approximately 3 days
Apparent terminal phase elimination constant (λz) of Ubrogepant
measured Up to approximately 3 days
Terminal phase elimination half-life (t1/2) of Ubrogepant
measured Up to approximately 3 days
Apparent total body clearance of drug from plasma after extravascular administration (CL/F) of Ubrogepant
measured Up to approximately 3 days
Apparent volume of distribution during the terminal phase after extravascular administration (Vz/F) of Ubrogepant
measured Up to approximately 3 days

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