A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
← catalyst calendarNCT07668414 · readout in 783 d
Sponsored by Novo Nordisk A/S (industry) · NVO — their whole pipeline →.
Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
650estimated
Sites
46
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-09-22 | estimated | When the study began enrolling |
| Primary completion | 2028-10-10 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-10-10 | estimated | The whole study's end, after follow-up |
| First posted | 2026-06-25 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-06-25 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Overweight
- Obesity
Interventions
- Drug: Zenagamtide
- Drug: Semaglutide
- Drug: Placebo (matched to semaglutide)
- Drug: Placebo (matched to zenagamtide)
Primary outcome
what the primary-completion date above is the date OFRelative change in body weight
measured From week 0 to week 84
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