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Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

← catalyst calendar

NCT07660198 · readout in 470 d

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Triple · Prevention
Enrollment
1,200estimated
Sites
44
Countries
Puerto Rico, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-06-15actualWhen the study began enrolling
Primary completion2027-12-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-12-02estimatedThe whole study's end, after follow-up
First posted2026-06-22actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-09actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Pneumococcal Disease

Interventions

  • Biological: PG4
  • Biological: 20-valent pneumococcal conjugate vaccine (20vPnC) — also filed as Prevnar 20

Primary outcomes

what the primary-completion date above is the date OF
Percentage of Participants With Local Reactions Within 7 Days After Vaccination
measured Within 7 days after Vaccination
Percentage of Participants With Systemic Events Within 7 Days after Vaccination
measured Within 7 days after Vaccination
Percentage of Participants With Adverse Events (AEs)
measured From Vaccination to 1 month after Vaccination
Percentage of Participants With Serious Adverse Events (SAEs)
measured From Vaccination to 6 months after Vaccination
GMCs of serotype-specific IgG concentrations
measured 1 month after vaccination
GMTs of serotype-specific OPA titers
measured 1 month after vaccination

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