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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

← catalyst calendar

NCT07654374 · readout ≤ 773 d

Sponsored by Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics (industry) · GPCR — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
1,100estimated
Sites
74
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-07-17actualWhen the study began enrolling
Primary completionSep 2028estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionNov 2028estimatedThe whole study's end, after follow-up
First posted2026-06-17actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Obesity
  • Overweight
  • Chronic Weight Management
  • Type2 Diabetes Mellitus

Interventions

  • Drug: aleniglipron
  • Drug: aleniglipron
  • Drug: aleniglipron
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Percent change in body weight from Baseline
measured Baseline and week 76

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