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Human ADME Study of [14C]-AZD1390

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NCT07643870 · readout in 602 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 1
Status
Not yet recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
8estimated
Sites
2
Country
United Kingdom

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-06-30estimatedWhen the study began enrolling
Primary completion2028-04-12estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-04-12estimatedThe whole study's end, after follow-up
First posted2026-06-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-12actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Advanced Solid Malignancies

Intervention

  • Drug: AZD1390

Primary outcomes

what the primary-completion date above is the date OF
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
The mass balance of total Radioactivity of AZD1390 and its metabolites after a single oral dose
measured 6 Weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 and the distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 after a single oral dose
measured 6 weeks
The distribution of total radioactivity into blood cells after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 after a single oral dose
measured 6 weeks
Pharmacokinetic(s) of AZD1390 after a single oral dose
measured 6 weeks

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