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Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study

← catalyst calendar

NCT07620574 · readout in 1,381 d

Sponsored by Exelixis (industry) · EXEL — their whole pipeline →. With Bristol-Myers Squibb.

Phase
Phase 3
Status
Enrolling by invitation
Study type
Interventional
Design
Na · None · Treatment
Enrollment
5,000estimated
Sites
2
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-07-30actualWhen the study began enrolling
Primary completion2030-05-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-05-31estimatedThe whole study's end, after follow-up
First posted2026-06-02actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-18actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Cancer
  • Renal Cell Carcinoma (RCC)
  • Pancreatic Neuroendocrine Tumors (pNET)
  • Extra-Pancreatic NET (epNET)
  • Hepatocellular Carcinoma (HCC)
  • Differentiated Thyroid Cancer (DTC)
  • Non-Clear Cell Renal Cell Carcinoma (nccRCC)
  • Colorectal Cancer
  • Prostate Cancer

Interventions

  • Drug: Cabozantinib — also filed as XL184, Cabometyx
  • Drug: Zanzalintinib — also filed as XL092
  • Drug: Atezolizumab
  • Drug: Nivolumab
  • Drug: Abiraterone
  • Drug: Prednisone
  • Drug: Enzalutamide

Primary outcome

what the primary-completion date above is the date OF
Number of Participants With Treatment Emergent Adverse Events (TEAEs)
measured Up to 4 years (until the event resolves, returns to baseline, stabilizes, a new anticancer therapy is initiated, or the participant is lost to follow-up or withdraws consent, whichever occurs first)

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