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A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

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NCT07614776 · readout in 345 d

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
304estimated
Sites
51
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-27actualWhen the study began enrolling
Primary completion2027-07-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-01-12estimatedThe whole study's end, after follow-up
First posted2026-05-29actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-17actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Neovascular Age-related Macular Degeneration
  • nAMD

Interventions

  • Drug: ABP 938 8 mg
  • Drug: Aflibercept (US) 8 mg — also filed as EYLEA HD

Primary outcome

what the primary-completion date above is the date OF
Change From Baseline in BCVA as measured by Early Treatment Diabetic Retinopathy Study (ETDRS) letter score
measured Baseline and Week 12

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