Signatera-Guided De-escalation of Adjuvant Therapy in Resectable Stage II-IVa Gastric/Gastric-Esophageal Cancer
← catalyst calendarNCT07565857 · readout ≤ 772 d
Sponsored by Natera, Inc. (industry) · NTRA — their whole pipeline →.
Phase
Not applicable
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
1,000estimated
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | Sep 2026 | estimated | When the study began enrolling |
| Primary completion | Sep 2028 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Sep 2034 | estimated | The whole study's end, after follow-up |
| First posted | 2026-05-04 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-05-04 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Gastric-Esophageal Cancer
Intervention
- Device: Signatera Genome ultra-sensitive ctDNA blood test
Primary outcome
what the primary-completion date above is the date OFDisease Free Survival (DFS)
measured 2 years from randomization to the first occurrence of disease recurrence or death from any cause, whichever occurs first
Publications
- PMID 21444866 — cited as background
- PMID 38297325 — cited as background
- PMID 26512615 — cited as background
- PMID 26114883 — cited as background
- PMID 28017807 — cited as background
- PMID 36959359 — cited as background
- PMID 9790335 — cited as background
- PMID 22585691 — cited as background
- PMID 22010012 — cited as background
- PMID 18669424 — cited as background
- PMID 39986705 — cited as background
- PMID 32856860 — cited as background
- PMID 39369091 — cited as background
- PMID 27226727 — cited as background
- PMID 38956557 — cited as background
- PMID 10973386 — cited as background
- PMID 30110194 — cited as background
- PMID 22977620 — cited as background
- PMID 40645642 — cited as background
- PMID 29543932 — cited as background
- PMID 38572751 — cited as background
- PMID 12115373 — cited as background
- PMID 34889947 — cited as background
- PMID 30982686 — cited as background
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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