A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
← catalyst calendarNCT07564596 · readout ≤ 407 d
Sponsored by Climb Bio, Inc. (industry) · CLYM — their whole pipeline →.
Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
30estimated
Sites
2
Country
China
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-06-30 | actual | When the study began enrolling |
| Primary completion | Sep 2027 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Sep 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2026-05-04 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-06 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Systemic Lupus Erthematosus
Intervention
- Drug: Budoprutug — also filed as TNT119
Primary outcomes
what the primary-completion date above is the date OFIncidence of Treatment-Emergent Adverse Events (TEAEs)
measured Up to week 28
Incidence of Clinical Laboratory Abnormalities
measured Up to week 28
Incidence of dose-limiting toxicities (DLTs)
measured up to 28 weeks
Change from Baseline in Systolic Blood Pressure
measured Up to week 28
Change from Baseline in Diastolic Blood Pressure
measured up to 28 weeks
Change from Baseline in Heart Rate
measured up to 28 weeks
Change from Baseline in Respiratory Rate
measured up to 28 weeks
Change from Baseline in Body Temperature
measured up to 28 weeks
Change from Baseline in PR Interval
measured up to 28 weeks
Change from Baseline in QRS Duration
measured up to 28 weeks
Change from Baseline in QT Interval
measured up to 28 weeks
Change from Baseline in QTc Interval
measured up to 28 weeks
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