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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

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NCT07545759 · readout ≤ 407 d

Sponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
531estimated
Sites
89
Countries
Belgium, Canada, China +7

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-06actualWhen the study began enrolling
Primary completionSep 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionNov 2027estimatedThe whole study's end, after follow-up
First posted2026-04-22actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Irritable Bowel Syndrome
  • Diarrhea

Interventions

  • Drug: LY3537031 — also filed as Brenipatide
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Percentage of Participants Who Had a Daily Composite Response for at Least 50 Percent (%) of Days
measured Week 9 to Week 16

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