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Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL

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NCT07516093 · readout ≤ 1,169 d

Sponsored by Nurix Therapeutics, Inc. (industry) · NRIX — their whole pipeline →.

Phase
Phase 3
Status
Not yet recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
620estimated

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
StartJun 2026estimatedWhen the study began enrolling
Primary completionOct 2029estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJun 2032estimatedThe whole study's end, after follow-up
First posted2026-04-07actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-08actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • B-cell Lymphoma
  • Chronic Lymphocytic Leukemia
  • Small Lymphocytic Lymphoma

Interventions

  • Drug: NX-5948 — also filed as Bexobrutideg
  • Drug: Pirtobrutinib — also filed as JAYPIRCA

Primary outcome

what the primary-completion date above is the date OF
Progression-free survival (PFS) as assessed by Independent Review Committee (IRC)
measured Up to approximately 3.5 years

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