A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity
← catalyst calendarNCT07508241 · readout in 160 d
Sponsored by Pfizer (industry) · PFE — their whole pipeline →.
Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Basic science
Enrollment
22actual
Sites
1
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-03-31 | actual | When the study began enrolling |
| Primary completion | 2027-01-27 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2027-01-27 | estimated | The whole study's end, after follow-up |
| First posted | 2026-04-02 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-07-09 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Obesity
- Overweight and/or Obesity
- Overweight
- Drug Interaction
Interventions
- Drug: PF-08653944 — also filed as MET097
- Drug: Acetaminophen — also filed as paracetamol
Primary outcomes
what the primary-completion date above is the date OFAcetaminophen Pharmacokinetic (PK) Parameters: Maximum observed plasma concentration (Cmax)
measured Day 1 pre-dose through approximately 11 Weeks after last dose of study intervention.
Acetaminophen PK parameters: Area under the plasma concentration (AUC)
measured Day 1 pre-dose through approximately 11 Weeks after last dose of study intervention.
Acetaminophen PK parameters: Time to Maximum concentration (Tmax)
measured Day 1 pre-dose through approximately 11 Weeks after last dose of study intervention.
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