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A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

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NCT07501702 · readout in 926 d

Sponsored by Vertex Pharmaceuticals Incorporated (industry) · VRTX — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
30estimated
Sites
26
Countries
Australia, Poland, United Kingdom +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-13actualWhen the study began enrolling
Primary completion2029-03-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-03-02estimatedThe whole study's end, after follow-up
First posted2026-03-30actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-03actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Myasthenia Gravis, Generalized

Interventions

  • Drug: Povetacicept
  • Drug: Placebo

Primary outcomes

what the primary-completion date above is the date OF
Percent change in Total Immunoglobulin G (IgG)
measured Baseline and At Week 12
Safety and Tolerability as Assessed by Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)
measured From Baseline Up to Week 116

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