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Odevixibat Outcomes in Patients With PFIC Versus an External Control Cohort (OvEC-PFIC)

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NCT07497724

Sponsored by Ipsen (industry) · IPN.PA — their whole pipeline →. With Erasmus Medical Center, University Medical Center Groningen.

Phase
Status
Active, not recruiting
Study type
Observational
Enrollment
200estimated
Sites
1
Country
France

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-04-26actualWhen the study began enrolling
Primary completion2026-08-01estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-09-30estimatedThe whole study's end, after follow-up
First posted2026-03-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-03actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • PFIC - Progressive Familial Intrahepatic Cholestasis

Primary outcomes

what the primary-completion date above is the date OF
Part A: Liver transplant-free survival (LTFS)
measured From the date of first odevixibat treatment or from the date of first registry entry into NAPPED group where OvEC cohort eligibility criteria were met, until the first occurrence of the defined event or last available follow-up (2017-2025)
Part B: Liver transplant-free survival (LTFS)
measured From the date of first odevixibat treatment (Odevixibat Cohort) or from the from the date of SBD (External control cohort) until the first occurrence of the defined event or last available follow-up (2017-2025)

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