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Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers

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NCT07493304 · readout in 1,784 d

Sponsored by Regeneron Pharmaceuticals (industry) · REGN — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
1,600estimated
Sites
6
Countries
South Korea, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-08-31estimatedWhen the study began enrolling
Primary completion2031-07-08estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2031-07-08estimatedThe whole study's end, after follow-up
First posted2026-03-25actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-19actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Venous Thromboembolism (VTE)

Interventions

  • Drug: REGN7508 — also filed as cenvacibart
  • Drug: Apixaban

Primary outcomes

what the primary-completion date above is the date OF
Occurrence of Treatment-Emergent Adverse Events (TEAEs)
measured Approximately 6 months
Severity of TEAEs
measured Approximately 6 months
Time-to-first event of centrally adjudicated recurrent VTE [DVT (symptomatic or asymptomatic [proximal] or Non-fatal PE (symptomatic or asymptomatic [in a segmental or larger pulmonary artery] )or VTE-related death)]
measured Up to approximately 3.5 years
Time-to-first event of centrally adjudicated International Society of Thrombosis and Hemostasis (ISTH)-defined major bleeding or Clinically Relevant Non-Major (CRNM) bleeding
measured Up to approximately 3.5 years

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