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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

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NCT07483099 · readout ≤ 315 d

Sponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
60estimated
Sites
70
Countries
Belgium, Brazil, Canada +7

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-04actualWhen the study began enrolling
Primary completionJun 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionMar 2028estimatedThe whole study's end, after follow-up
First posted2026-03-19actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Crohn Disease

Interventions

  • Drug: LY4395089
  • Drug: Mirikizumab - Intravenous (IV) — also filed as LY3074828
  • Drug: Mirikizumab - Subcutaneous (SC) — also filed as LY3074828

Primary outcome

what the primary-completion date above is the date OF
Percentage of Participants with Crohn's Disease who Achieve Endoscopic Response
measured Baseline, Up to Week 12

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