Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

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NCT07476287 · readout in 577 d

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase

Phase 2

Status

Recruiting

Study type

Interventional

Design

Na · None · Treatment

Enrollment

40estimated

Sites

Countries

Brazil, China, France +7

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis

Date

Filed

Basis

What it is

Start

2026-07-02

actual

When the study began enrolling

Primary completion

2028-03-19

estimated

The date the last participant is measured for the primary outcome — the readout window

Study completion

2031-03-19

estimated

The whole study's end, after follow-up

First posted

2026-03-17

actual

When this record first appeared on the registry

Results posted

—

When the sponsor posted results to the registry

Record updated

2026-08-17

actual

The sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

Small Cell Lung Cancer
Small Cell Lung Cancer ( SCLC )
Transformed Small Cell Lung Cancer
Lung Neoplasms
Carcinoma, Small Cell Lung
Small Cell Cancer Of The Lung

Interventions

Drug: PF-08634404 — also filed as SSGJ-707
Drug: Chemotherapy

Primary outcomes

what the primary-completion date above is the date OF

Confirmed Objective Response Rate (ORR) as assessed by investigator based on Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST v1.1)

measured From start of treatment until first documented CR or PR (approximately maximum up to 1 years)

Number of Participants with Adverse Events (AEs)

measured Up to 90 days after the last dose of treatment

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