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Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide

← catalyst calendar

NCT07454837 · readout in 377 d

Sponsored by Mirum Pharmaceuticals, Inc. (industry) · MIRM — their whole pipeline →.

Phase
Phase 2/3
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
120estimated
Sites
35
Countries
Austria, Czechia, France +5

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-02-26actualWhen the study began enrolling
Primary completion2027-08-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-03-30estimatedThe whole study's end, after follow-up
First posted2026-03-06actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-29actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Chronic Hepatitis D

Interventions

  • Drug: Brelovitug (BJT-778) — also filed as BJT-778
  • Drug: Bulevirtide — also filed as BJT-778, Hepcludex

Primary outcome

what the primary-completion date above is the date OF
Proportion of participants with undetectable HDV RNA (<LLOQ Target not detected [TND])
measured Week 24

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