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FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

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NCT07446322 · readout in 376 d

Sponsored by Oncolytics Biotech (industry) · ONCY — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
60estimated
Sites
13
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-04-30actualWhen the study began enrolling
Primary completion2027-08-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-04-30estimatedThe whole study's end, after follow-up
First posted2026-03-03actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-19actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Ras-mutated Metastatic Colorectal Cancer
  • mCRC
  • MSS Metastatic Colorectal Cancer

Interventions

  • Drug: Bevacizumab — also filed as Avastin
  • Drug: FOLFIRI
  • Drug: Pelareorep

Primary outcome

what the primary-completion date above is the date OF
Overall Response Rate (ORR)
measured At week 8

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