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A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults

← catalyst calendar

NCT07444294 · readout in 120 d

Sponsored by Scholar Rock, Inc. (industry) · SRRK — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
76estimated
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-11-21actualWhen the study began enrolling
Primary completion2026-12-17estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-06-09estimatedThe whole study's end, after follow-up
First posted2026-03-02actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-02actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Healthy

Interventions

  • Drug: Placebo
  • Drug: SRK-439
  • Drug: SRK-439

Primary outcomes

what the primary-completion date above is the date OF
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks
Evaluate the safety and tolerability of single and multiple SRK-439 SC dose administration in healthy adult participants
measured Up to 32 weeks

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