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An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

← catalyst calendar

NCT07438405 · readout in 528 d

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
30estimated
Sites
8
Countries
Poland, Spain, Taiwan +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-05-07actualWhen the study began enrolling
Primary completion2028-01-29estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-07-14estimatedThe whole study's end, after follow-up
First posted2026-02-27actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-23actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Thyroid Eye Disease

Intervention

  • Drug: AMG 732

Primary outcome

what the primary-completion date above is the date OF
Number of Participants who are Proptosis Responders in the Trial Eye at Week 24 in Participants with TED who are Defined as Primary Nonresponders or Relapsed During the Safety Follow-up in the Parent Trial
measured Week 24

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