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A Phase 1, Open-Label, Parallel-Group, Single-Dose Study To Compare The Pharmakokinetics Of TNX-102 SL (Cyclobenzaprine Hydrochloride Sublingual Tablet) In Non-Elderly Versus Elderly Participants

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NCT07413367

Sponsored by Tonix Pharmaceuticals, Inc. (industry) · TNXP — their whole pipeline →. With Syneos Health.

Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Basic science
Enrollment
50actual
Sites
1
Country
Canada

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-12-09actualWhen the study began enrolling
Primary completion2026-02-10estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-02-10estimatedThe whole study's end, after follow-up
First posted2026-02-17actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-02-17actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Pharmakokinetic
  • Open Label
  • Phase 1

Intervention

  • Drug: TNX-102 SL Tablet

Primary outcomes

what the primary-completion date above is the date OF
AUC0-inf: Area Under the curve from time zero to infinity
measured From dosing day to end of treatment at 16 days
AUC0-t: Area Under the Curve from time zero to the last measurable concentration
measured From dosing day to end of treatment at 16 days
Cmax: Maximum Plasma Concentration
measured From dosing day to end of treatment at 16 days

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