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Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease

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NCT07404865 · readout ≤ 865 d

Sponsored by Vor Biopharma (industry) · VOR — their whole pipeline →.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
250estimated
Sites
38
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2026-02-26actualWhen the study began enrolling
Primary completionDec 2028estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJan 2029estimatedThe whole study's end, after follow-up
First posted2026-02-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Primary Sjogren's Disease

Interventions

  • Biological: Telitacicept — also filed as RC18, RC18-L
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
To evaluate the efficacy of telitacicept versus placebo at Week 48 in the change from baseline in the EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) score at Week 48.
measured Week 48

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