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Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

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NCT07400588 · readout ≤ 42 d

Sponsored by Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics (industry) · GPCR — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
58actual
Sites
16
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2025-12-01actualWhen the study began enrolling
Primary completionSep 2026estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionSep 2026estimatedThe whole study's end, after follow-up
First posted2026-02-10actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-27actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Obese
  • Obesity
  • Obesity Type 2 Diabetes Mellitus
  • Weight Loss

Interventions

  • Drug: Aleniglipron
  • Drug: Placebo

Primary outcomes

what the primary-completion date above is the date OF
Incidence, severity and relationship of AEs/SAEs
measured Baseline to week 31
Assessment of vital signs
measured Baseline to week 31
Assessment of laboratory measures
measured Baseline to week 31
Assessment of Electrocardiograms (ECG)
measured Baseline to week 31

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