Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
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Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
30estimated
Sites
2
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2026-02-20 | actual | When the study began enrolling |
| Primary completion | 2026-06-15 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-07-01 | estimated | The whole study's end, after follow-up |
| First posted | 2026-01-15 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-02-27 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Chronic Hepatitis B Infection
Intervention
- Drug: Pevifoscorvir Sodium (ALG-000184)
Primary outcomes
what the primary-completion date above is the date OFArea under the concentration time curve [AUC]
measured Up to 4 days
Maximum plasma concentration [Cmax]
measured Up to 4 Days
Minimum plasma concentration [Cmin]
measured Up to 4 Days
C0 [predose]
measured Up to 4 days
Half-life [t1/2]
measured Up to 4 Days
Time to maximum plasma concentration [Tmax]
measured Up to 4 Days
Apparent Clearance (CL/F)
measured Up to 4 Days
Apparent Volume of Distribution (V/F)
measured Up to 4 Days
Total Amount of Drug Excreted in Urine (Ae)
measured Up to 4 Days
Renal Clearance (CLr)
measured Up to 4 Days
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